Aliases for TBL3 Gene
External Ids for TBL3 Gene
Previous GeneCards Identifiers for TBL3 Gene
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. [provided by RefSeq, Jul 2008]
GeneCards Summary for TBL3 Gene
TBL3 (Transducin Beta Like 3) is a Protein Coding gene. Diseases associated with TBL3 include Autosomal Dominant Polycystic Kidney Disease. Among its related pathways are Gene Expression and rRNA processing in the nucleus and cytosol. Gene Ontology (GO) annotations related to this gene include snoRNA binding. An important paralog of this gene is APAF1.