Aliases for TBKBP1 Gene
External Ids for TBKBP1 Gene
Previous GeneCards Identifiers for TBKBP1 Gene
TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway (Bouwmeester et al., 2004 [PubMed 14743216]).[supplied by OMIM, Mar 2008]
GeneCards Summary for TBKBP1 Gene
TBKBP1 (TBK1 Binding Protein 1) is a Protein Coding gene. Diseases associated with TBKBP1 include Vaccinia. Among its related pathways are RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways and NF-kappaB Signaling. An important paralog of this gene is AZI2.
UniProtKB/Swiss-Prot Summary for TBKBP1 Gene
Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.