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Aliases for TBC1D8 Gene
Aliases for TBC1D8 Gene
External Ids for TBC1D8 Gene
- HGNC: 17791
- NCBI Entrez Gene: 11138
- Ensembl: ENSG00000204634
- UniProtKB/Swiss-Prot: O95759
Previous GeneCards Identifiers for TBC1D8 Gene
- GC02M101228
- GC02M101245
- GC02M101082
- GC02M100990
- GC02M101622
- GC02M095387
Summaries for TBC1D8 Gene
GeneCards Summary for TBC1D8 Gene
TBC1D8 (TBC1 Domain Family Member 8) is a Protein Coding gene. Among its related pathways are Cell cycle. Gene Ontology (GO) annotations related to this gene include calcium ion binding and GTPase activator activity. An important paralog of this gene is TBC1D8B.
UniProtKB/Swiss-Prot Summary for TBC1D8 Gene
-
May act as a GTPase-activating protein for Rab family protein(s).
Additional gene information for TBC1D8 Gene
- HGNC (17791)
- NCBI Entrez Gene (11138)
- Ensembl (ENSG00000204634)
- UniProtKB/Swiss-Prot (O95759)
- Open Targets Platform(ENSG00000204634)
- Monarch Initiative
- Search for TBC1D8 at DataMed
- Search for TBC1D8 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TBC1D8 Gene
Genomics for TBC1D8 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TBC1D8 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TBC1D8 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TBC1D8
- Top Transcription factor binding sites by QIAGEN in the TBC1D8 gene promoter:
-
- aMEF-2
- FOXO1
- FOXO1a
- FOXO4
- MEF-2
- MEF-2A
- Pax-2
- Pax-2a
- Pax-2b
- RORalpha1
Genomic Locations for TBC1D8 Gene
Latest Assembly
- chr2:101,006,435-101,252,866
- (GRCh38/hg38)
- Size:
- 246,432 bases
- Orientation:
- Minus strand
Previous Assembly
- chr2:101,623,690-101,767,844
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 144,155 bases
- Orientation:
- Minus strand
- chr2:101,624,079-101,869,328
- (GRCh37/hg19 by Ensembl)
- Size:
- 245,250 bases
- Orientation:
- Minus strand
Genomic View for TBC1D8 Gene
Genes around TBC1D8 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q11.2 by HGNC
- 2q11.2 by Entrez Gene
- 2q11.2 by Ensembl
TBC1D8 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TBC1D8 Gene
Proteins for TBC1D8 Gene
-
Protein details for TBC1D8 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95759-TBCD8_HUMAN
- Recommended name:
- TBC1 domain family member 8
- Protein Accession:
- O95759
- A6NDL4
- A8K9W1
- B9A6K4
- Q53SQ4
- Q9UQ32
Protein attributes for TBC1D8 Gene
- Size:
- 1140 amino acids
- Molecular mass:
- 130835 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAY14824.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAF85515.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for TBC1D8 Gene
Post-translational modifications for TBC1D8 Gene
Other Protein References for TBC1D8 Gene
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for TBC1D8
- Novus Biologicals Antibodies for TBC1D8
- Invitrogen Antibodies for TBC1D8 (AFLGC-TBC1D8)
-
Custom Antibody ServicesProSci Antibodies for TBC1D8
-
Santa Cruz Biotechnology (SCBT) Antibodies for TBC1D8
Protein products for research
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TBC1D8
- Origene Custom Protein Services for TBC1D8
- Novus Biologicals proteins for TBC1D8
- antibodies-online: Show 3 available TBC1D8 Proteins ranked by validation data
- Compare Top TBC1D8 Proteins
-
Quality Products:
-
Abcam proteins for TBC1D8
Assay products for research
No data available for DME Specific Peptides for TBC1D8 Gene
Domains & Families for TBC1D8 Gene
Gene Families for TBC1D8 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for TBC1D8 Gene
- InterPro:
- Blocks:
-
- RabGAP/TBC domain
- GRAM domain
- ProtoNet:
Suggested Antigen Peptide Sequences for TBC1D8 Gene
- GenScript: Design optimal peptide antigens:
-
- Vascular Rab-GAP/TBC-containing protein (TBCD8_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O95759UniProtKB/Swiss-Prot:
TBCD8_HUMAN :- The arginine and glutamine fingers are critical for the GTPase-activating mechanism, they pull out Rab's 'switch 2' glutamine and insert in Rab's active site.
- Domain:
-
- The arginine and glutamine fingers are critical for the GTPase-activating mechanism, they pull out Rab's 'switch 2' glutamine and insert in Rab's active site.
Function for TBC1D8 Gene
Molecular function for TBC1D8 Gene
- UniProtKB/Swiss-Prot Function:
- May act as a GTPase-activating protein for Rab family protein(s).
Phenotypes From GWAS Catalog for TBC1D8 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IEA,IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 32296183 |
| GO:0031267 | small GTPase binding | IBA | -- |
Phenotypes for TBC1D8 Gene
- MGI mutant phenotypes for TBC1D8:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TBC1D8:
-
- Increased gamma-H2AX phosphorylation
- Decreased hepcidin::fluc mRNA expression
- no effect
- Decreased ionizing radiation sensitivity
- Decreased viability
- Decreased NF-kappaB reporter expression
- Increased shRNA abundance (Z-score > 2)
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased shRNA abundance (Z-score < -2)
- Decreased shRNA abundance
- Decreased epidermal growth factor (EGF) endocytosis, decreased transferrin (TF) endocytosis
- Increased IL-8 secretion
- Increased G1 length
- Increased S length
- Increased S length, increased G2 length
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TBC1D8 - Starting at $85 >
- * TBC1D8 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TBC1D8
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TBC1D8
-
Santa Cruz Biotechnology (SCBT) CRISPR for TBC1D8
miRNA for TBC1D8 Gene
- miRTarBase miRNAs that target TBC1D8
-
- hsa-miR-335-5p (MIRT019002)
- hsa-miR-488-3p (MIRT445539)
- hsa-miR-4635 (MIRT445540)
- hsa-miR-145-3p (MIRT445541)
- hsa-miR-7161-3p (MIRT445542)
- hsa-miR-548ah-5p (MIRT445543)
- hsa-miR-3609 (MIRT445544)
- hsa-miR-4685-3p (MIRT553744)
- hsa-miR-4287 (MIRT553745)
- hsa-miR-4666a-3p (MIRT553746)
- hsa-miR-6849-5p (MIRT553747)
- hsa-miR-3681-5p (MIRT553748)
- hsa-miR-7849-3p (MIRT553749)
- hsa-miR-25-3p (MIRT553750)
- hsa-miR-32-5p (MIRT553751)
- hsa-miR-363-3p (MIRT553752)
- hsa-miR-367-3p (MIRT553753)
- hsa-miR-92a-3p (MIRT553754)
- hsa-miR-92b-3p (MIRT553755)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TBC1D8
- Browse OriGene Inhibitory RNA Products For TBC1D8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TBC1D8
Clone products for research
- Applied Biological Materials (abm): Clones for TBC1D8 - Starting at $45 >
- * TBC1D8 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for TBC1D8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TBC1D8
Cell Lines for research
-
Horizon Cell Lines for TBC1D8
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TBC1D8 Gene
Localization for TBC1D8 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| plasma membrane | 0 |
| peroxisome | 0 |
- Nuclear speckles (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | TAS | 10373574 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for TBC1D8 Gene
Pathways & Interactions for TBC1D8 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cell cycle |
.58
|
|
Pathways by source for TBC1D8 Gene
1 BioSystems pathway for TBC1D8 Gene
Interacting Proteins for TBC1D8 Gene
Selected Interacting proteins:
O95759-TBCD8_HUMAN
ENSP00000366036
for TBC1D8 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for TBC1D8
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006886 | intracellular protein transport | IBA | 21873635 |
| GO:0008015 | blood circulation | TAS | 10373574 |
| GO:0008284 | positive regulation of cell proliferation | TAS | 10373574 |
| GO:0043547 | positive regulation of GTPase activity | IEA | -- |
| GO:0090630 | activation of GTPase activity | IBA | 21873635 |
No data available for SIGNOR curated interactions for TBC1D8 Gene
Transcripts for TBC1D8 Gene
mRNA/cDNA for TBC1D8 Gene
- 3 REFSEQ mRNAs :
- 15 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000376840 3627 nts (view in UCSC)
- ENST00000409318 4190 nts (view in UCSC)
- ENST00000462819 580 nts (view in UCSC)
- ENST00000463469 561 nts (view in UCSC)
- ENST00000473937 1093 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TBC1D8 - Starting at $85 >
- * TBC1D8 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TBC1D8
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TBC1D8
-
Santa Cruz Biotechnology (SCBT) CRISPR for TBC1D8
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TBC1D8
- Browse OriGene Inhibitory RNA Products For TBC1D8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TBC1D8
Clone products for research
- Applied Biological Materials (abm): Clones for TBC1D8 - Starting at $45 >
- * TBC1D8 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for TBC1D8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TBC1D8
Relevant External Links for TBC1D8 Gene
- GeneLoc Exon Structure for
- TBC1D8
Expression for TBC1D8 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
- Monocytes Peripheral Blood
-
Eye (Sensory Organs)
- Mature Rod Cells Outer Nuclear Layer
-
Neurons
- Mature Rod Cells Outer Nuclear Layer
mRNA differential expression in normal tissues according to GTEx for TBC1D8 Gene
This gene is overexpressed in Muscle - Skeletal (x6.2).
This gene is overexpressed in Ovary (21.6), Testis (16.3), Monocytes (8.2), and Islet of Langerhans (6.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TBC1D8 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TBC1D8
SOURCE GeneReport for Unigene cluster for TBC1D8 Gene:
Hs.442657Evidence on tissue expression from TISSUES for TBC1D8 Gene
- Nervous system(4.3)
Primer products for research
-
OriGene qPCR primer pairs for TBC1D8
Gene Expression Assays for research
No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TBC1D8 Gene
Orthologs for TBC1D8 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TBC1D8 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TBC1D8 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TBC1D8 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Tbc1d8 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | TBC1D8 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Tbc1d8 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TBC1D8 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | TBC1D8 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | TBC1D8 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tbc1d8 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | tbc1d8 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.3902 31 |
|
OneToMany |
- Species where no ortholog for TBC1D8 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for TBC1D8 Gene
- ENSEMBL:
- Gene Tree for TBC1D8 (if available)
- TreeFam:
- Gene Tree for TBC1D8 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TBC1D8: view image
Paralogs for TBC1D8 Gene
Paralogs for TBC1D8 Gene
- TBC1D8B 5
- TBC1D9 5
- TBC1D9B 5
- SGSM3 5
- TBCK 5
- EVI5 5
- TBC1D4 5
- EVI5L 5
- USP6NL 5
- TBC1D2 5
- RABGAP1 5
- TBC1D10B 5
- TBC1D2B 5
- TBC1D10A 5
- TBC1D1 5
- SGSM1 5
- TBC1D10C 5
- TBC1D17 5
- RABGAP1L 5
- TBC1D25 5
- GRTP1 5
- SGSM2 5
- TBC1D22A 5
- TBC1D12 5
- TBC1D3B 5
- TBC1D3I 5
- TBC1D3G 5
- TBC1D3H 5
- TBC1D3K 5
- TBC1D3L 5
- TBC1D3D 5
- TBC1D3C 5
- TBC1D3E 5
- TBC1D3 5
- TBC1D30 5
- TBC1D15 5
- ENSG00000248751 5
- TBC1D14 5
- TBC1D5 5
- TBC1D22B 5
- TBC1D13 5
- TBC1D3F 5
- TBC1D16 5
- ENSG00000288591 5
- TBC1D21 5
- TBC1D26 5
- TBC1D28 5
(9) SIMAP similar genes for TBC1D8 Gene using alignment to 2 proteins:
- TBCD8_HUMAN
- J3KQ40_HUMAN
Variants for TBC1D8 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TBC1D8 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs34425369 | Benign: not provided | 101,040,286(-) |
C/T NM_001330348.1(TBC1D8):c.972G>A (p.Thr324=) |
NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS | |
| rs78556703 | Benign: not provided | 101,054,214(-) |
G/A NM_001330348.1(TBC1D8):c.525C>T (p.Val175=) |
NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS | |
| rs78831774 | Benign: not provided | 101,008,064(-) |
A/G NM_001330348.1(TBC1D8):c.3225T>C (p.Phe1075=) |
NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT,INTRON | |
| rs1057580 | - |
p.Phe1073Leu |
|||
| rs1062062 | - |
p.Gly954Arg |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2720446 | CNV | deletion | 23290073 |
| esv34123 | CNV | loss | 18971310 |
| esv3591762 | CNV | loss | 21293372 |
| nsv1133480 | CNV | deletion | 24896259 |
| nsv519123 | CNV | loss | 19592680 |
| nsv834316 | CNV | gain | 17160897 |
| nsv834317 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
43.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.83;
86.92% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TBC1D8 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TBC1D8 Gene
Disorders for TBC1D8 Gene
Additional Disease Information for TBC1D8
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for TBC1D8 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TBC1D8 Gene
Publications for TBC1D8 Gene
- Antisense display--a method for functional gene screening: evaluation in a cell-free system and isolation of angiogenesis-related genes. (PMID: 10373574) Yonekura H … Yamamoto H (Nucleic acids research 1999) 2 3 4
- An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. (PMID: 20548944) Hsu YH … Kiel DP (PLoS genetics 2010) 3 41
- Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. (PMID: 19077034) Ishibashi K … Fukuda M (Genes to cells : devoted to molecular & cellular mechanisms 2009) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
ExternalLinks
Products for TBC1D8 Gene
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- antibodies-online: Show 8 available TBC1D8 Antibodies ranked by validation data
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- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TBC1D8
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TBC1D8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TBC1D8
Sources for TBC1D8 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB