Aliases for TBC1D23 Gene
External Ids for TBC1D23 Gene
Previous GeneCards Identifiers for TBC1D23 Gene
GeneCards Summary for TBC1D23 Gene
UniProtKB/Swiss-Prot for TBC1D23 Gene
Putative Rab GTPase-activating protein which plays a role in vesicular trafficking (PubMed:28823707). Plays a role in brain development, including in cortical neuron positioning (By similarity). May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity). May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge (By similarity).