Aliases for TBC1D2 Gene
External Ids for TBC1D2 Gene
Previous GeneCards Identifiers for TBC1D2 Gene
GeneCards Summary for TBC1D2 Gene
TBC1D2 (TBC1 Domain Family Member 2) is a Protein Coding gene. Diseases associated with TBC1D2 include Suppurative Cholangitis and Facial Neuralgia. Among its related pathways are Vesicle-mediated transport and TBC/RABGAPs. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and cadherin binding. An important paralog of this gene is TBC1D2B.
UniProtKB/Swiss-Prot Summary for TBC1D2 Gene
Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.