Aliases for TBC1D15 Gene
External Ids for TBC1D15 Gene
Previous GeneCards Identifiers for TBC1D15 Gene
This gene encodes a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2/Bub2/Cdc16 domain. The encoded protein interacts with Ras-like protein in brain 5A and may function as a regulator of intracellular trafficking. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
GeneCards Summary for TBC1D15 Gene
TBC1D15 (TBC1 Domain Family Member 15) is a Protein Coding gene. Diseases associated with TBC1D15 include 3-Methylglutaconic Aciduria, Type Iii and Parkinson Disease, Late-Onset. Among its related pathways are TBC/RABGAPs and Mitophagy - animal. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is TBC1D17.
UniProtKB/Swiss-Prot Summary for TBC1D15 Gene
Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6 (By similarity).