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Aliases for TBC1D10A Gene
Aliases for TBC1D10A Gene
External Ids for TBC1D10A Gene
- HGNC: 23609
- NCBI Entrez Gene: 83874
- Ensembl: ENSG00000099992
- OMIM®: 610020
- UniProtKB/Swiss-Prot: Q9BXI6
Previous HGNC Symbols for TBC1D10A Gene
- TBC1D10
Previous GeneCards Identifiers for TBC1D10A Gene
- GC22M029016
- GC22M029017
- GC22M030683
- GC22M013649
- GC22M030687
Summaries for TBC1D10A Gene
GeneCards Summary for TBC1D10A Gene
TBC1D10A (TBC1 Domain Family Member 10A) is a Protein Coding gene. Diseases associated with TBC1D10A include Hyperhidrosis, Gustatory. Among its related pathways are Vesicle-mediated transport and Deregulation of Rab and Rab Effector Genes in Bladder Cancer. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and PDZ domain binding. An important paralog of this gene is TBC1D10B.
UniProtKB/Swiss-Prot Summary for TBC1D10A Gene
-
Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A.
Additional gene information for TBC1D10A Gene
- HGNC (23609)
- NCBI Entrez Gene (83874)
- Ensembl (ENSG00000099992)
- OMIM® (610020)
- UniProtKB/Swiss-Prot (Q9BXI6)
- Open Targets Platform(ENSG00000099992)
- Search for TBC1D10A at DataMed
- Search for TBC1D10A at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TBC1D10A Gene
Genomics for TBC1D10A Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TBC1D10A Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TBC1D10A on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TBC1D10A
- Top Transcription factor binding sites by QIAGEN in the TBC1D10A gene promoter:
-
- E2F
- E2F-1
- E2F-2
- E2F-3a
- E2F-4
- E2F-5
- GATA-2
- LCR-F1
- NF-1
Genomic Locations for TBC1D10A Gene
Latest Assembly
- chr22:30,291,990-30,326,947
- (GRCh38/hg38)
- Size:
- 34,958 bases
- Orientation:
- Minus strand
Previous Assembly
- chr22:30,687,979-30,722,930
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 34,952 bases
- Orientation:
- Minus strand
- chr22:30,687,979-30,723,035
- (GRCh37/hg19 by Ensembl)
- Size:
- 35,057 bases
- Orientation:
- Minus strand
Genomic View for TBC1D10A Gene
Genes around TBC1D10A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q12.2 by HGNC
- 22q12.2 by Entrez Gene
- 22q12.2 by Ensembl
TBC1D10A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TBC1D10A Gene
Proteins for TBC1D10A Gene
-
Protein details for TBC1D10A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BXI6-TB10A_HUMAN
- Recommended name:
- TBC1 domain family member 10A
- Protein Accession:
- Q9BXI6
- B3KXT8
- O76053
- Q20WK7
- Q543A2
Protein attributes for TBC1D10A Gene
- Size:
- 508 amino acids
- Molecular mass:
- 57118 Da
- Quaternary structure:
-
- Binds to the first PDZ domain of SLC9A3R1 and SLC9A3R2.
- SequenceCaution:
-
- Sequence=AAC23434.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for TBC1D10A Gene
Post-translational modifications for TBC1D10A Gene
- Exists in both phosphorylated and non-phosphorylated state.
-
Ubiquitination at Lys137 and Lys322
- NX_Q9BXI6 (NX_Q9BXI6-1)
- Modification sites at PhosphoSitePlus
Other Protein References for TBC1D10A Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences TBC1D10A Antibody
-
Custom Antibody ServicesOriGene Antibodies for TBC1D10A
- Novus Biologicals Antibodies for TBC1D10A
- Invitrogen Antibodies for TBC1D10A (AFLGC-TBC1D10A)
-
Biorbyt antibodies for TBC1D10A
-
Custom Antibody ServicesProSci Antibodies for TBC1D10A
-
Santa Cruz Biotechnology (SCBT) Antibodies for TBC1D10A
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for TBC1D10A
- Origene Custom Protein Services for TBC1D10A
Assay products for research
No data available for DME Specific Peptides for TBC1D10A Gene
Domains & Families for TBC1D10A Gene
Gene Families for TBC1D10A Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for TBC1D10A Gene
- InterPro:
- Blocks:
-
- RabGAP/TBC domain
- ProtoNet:
Suggested Antigen Peptide Sequences for TBC1D10A Gene
- GenScript: Design optimal peptide antigens:
-
- TBC1 domain family, member 10A (A7E244_HUMAN)
- cDNA FLJ46048 fis, clone SYNOV2017179, highly similar to TBC1 domain family member 10A (B3KXT8_HUMAN)
- TBC1 domain family, member 10A (B7ZVY9_HUMAN)
- TBC1 domain family, member 10A, isoform CRA_d (Q20WK7_HUMAN)
- Rab27A-GAP-alpha (TB10A_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9BXI6UniProtKB/Swiss-Prot:
TB10A_HUMAN :- The arginine and glutamine fingers are critical for the GTPase-activating mechanism, they pull out Rab's 'switch 2' glutamine and insert in Rab's active site.
- Domain:
-
- The arginine and glutamine fingers are critical for the GTPase-activating mechanism, they pull out Rab's 'switch 2' glutamine and insert in Rab's active site.
Function for TBC1D10A Gene
Molecular function for TBC1D10A Gene
- UniProtKB/Swiss-Prot Function:
- Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A.
Phenotypes From GWAS Catalog for TBC1D10A Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | IEA | -- |
| GO:0005096 | GTPase activator activity | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 11285285 |
| GO:0030165 | PDZ domain binding | IPI | 11285285 |
| GO:0031267 | small GTPase binding | IBA | -- |
Phenotypes for TBC1D10A Gene
- MGI mutant phenotypes for TBC1D10A:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TBC1D10A:
-
- Increased gamma-H2AX phosphorylation
- no effect
- Mildly decreased CFP-tsO45G cell surface transport
- Increased transferrin (TF) endocytosis
- Decreased POU5F1-GFP protein expression
- Decreased HIV-LTR-beta-galactosidase protein expression
- Decreased Salmonella proliferation
- Decreased OCT4 protein expression
- Decreased NANOG protein expression
- Decreased centriole number
Animal Models for TBC1D10A Gene
- MGI Knock Outs for TBC1D10A:
-
- Tbc1d10a Tbc1d10a<tm2a(EUCOMM)Wtsi>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TBC1D10A - Starting at $85 >
- * TBC1D10A CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TBC1D10A
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TBC1D10A
-
Santa Cruz Biotechnology (SCBT) CRISPR for TBC1D10A
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TBC1D10A
- Browse OriGene Inhibitory RNA Products For TBC1D10A
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TBC1D10A
Clone products for research
- Applied Biological Materials (abm): Clones for TBC1D10A - Starting at $45 >
- * TBC1D10A as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for TBC1D10A
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TBC1D10A
Cell Lines for research
-
Horizon Cell Lines for TBC1D10A
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TBC1D10A Gene
Localization for TBC1D10A Gene
Subcellular locations from UniProtKB/Swiss-Prot for TBC1D10A Gene
- Cell projection, microvillus. Note=Localizes to the microvilli-rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 4 |
| cytosol | 3 |
| endosome | 2 |
| cytoskeleton | 1 |
| nucleus | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Plasma membrane (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | IEA | -- |
| GO:0005886 | plasma membrane | IDA | 17562788 |
| GO:0005902 | microvillus | TAS | 11285285 |
| GO:0042995 | cell projection | IEA | -- |
| GO:0070062 | extracellular exosome | HDA | 19056867 |
Pathways & Interactions for TBC1D10A Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Vesicle-mediated transport | ||
| 2 | TBC/RABGAPs | ||
| 3 | Deregulation of Rab and Rab Effector Genes in Bladder Cancer | ||
Pathways by source for TBC1D10A Gene
1 BioSystems pathway for TBC1D10A Gene
3 Reactome pathways for TBC1D10A Gene
Interacting Proteins for TBC1D10A Gene
Selected Interacting proteins:
Q9BXI6-TB10A_HUMAN
ENSP00000384996
for TBC1D10A Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for TBC1D10A
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006886 | intracellular protein transport | IBA | 21873635 |
| GO:0042147 | retrograde transport, endosome to Golgi | IMP | 17562788 |
| GO:0045862 | positive regulation of proteolysis | IDA | 18387192 |
| GO:0090630 | activation of GTPase activity | IBA | 21873635 |
| GO:0097202 | activation of cysteine-type endopeptidase activity | IDA | 18387192 |
No data available for SIGNOR curated interactions for TBC1D10A Gene
Transcripts for TBC1D10A Gene
mRNA/cDNA for TBC1D10A Gene
- 2 REFSEQ mRNAs :
- 15 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000215790 1972 nts (view in UCSC)
- ENST00000393906 578 nts (view in UCSC)
- ENST00000403362 1833 nts (view in UCSC)
- ENST00000403477 1950 nts (view in UCSC)
- ENST00000433426 2021 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TBC1D10A - Starting at $85 >
- * TBC1D10A CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TBC1D10A
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TBC1D10A
-
Santa Cruz Biotechnology (SCBT) CRISPR for TBC1D10A
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TBC1D10A
- Browse OriGene Inhibitory RNA Products For TBC1D10A
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TBC1D10A
Clone products for research
- Applied Biological Materials (abm): Clones for TBC1D10A - Starting at $45 >
- * TBC1D10A as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for TBC1D10A
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TBC1D10A
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||||
| SP9: |
Relevant External Links for TBC1D10A Gene
- GeneLoc Exon Structure for
- TBC1D10A
Expression for TBC1D10A Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Placenta (Extraembryonic Tissues)
This gene is overexpressed in Peripheral blood mononuclear cells (13.7), Placenta (12.3), Breast (10.3), and Testis (8.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TBC1D10A Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TBC1D10A
SOURCE GeneReport for Unigene cluster for TBC1D10A Gene:
Hs.655273Evidence on tissue expression from TISSUES for TBC1D10A Gene
- Nervous system(4.7)
- Liver(4.1)
Primer products for research
-
OriGene qPCR primer pairs for TBC1D10A
-
OriGene qPCR primer pairs and template standards for TBC1D10A
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TBC1D10A Gene
Orthologs for TBC1D10A Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TBC1D10A 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | TBC1D10A 30 |
|
||
| -- 31 |
|
OneToMany | |||
| Cow (Bos Taurus) |
Mammalia | TBC1D10A 30 31 |
|
OneToMany | |
| Mouse (Mus musculus) |
Mammalia | Tbc1d10a 30 17 31 |
|
OneToMany | |
| Rat (Rattus norvegicus) |
Mammalia | Tbc1d10a 30 |
|
||
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
| TBC1D10A 30 |
|
||||
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tbc1d10a 30 |
|
||
| Str.17286 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.10297 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | tbc1d10a 30 31 |
|
ManyToMany | |
| si:ch211-87l2.1 31 |
|
ManyToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | wkd 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | tbc-10 30 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | MSB4 31 |
|
ManyToMany | |
| MSB3 31 |
|
ManyToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.6221 31 |
|
OneToMany |
- Species where no ortholog for TBC1D10A was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for TBC1D10A Gene
- ENSEMBL:
- Gene Tree for TBC1D10A (if available)
- TreeFam:
- Gene Tree for TBC1D10A (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TBC1D10A: view image
Paralogs for TBC1D10A Gene
Paralogs for TBC1D10A Gene
- TBC1D10B 5
- ENSG00000248751 5
- TBC1D10C 5
- TBC1D8 5
- TBC1D9 5
- TBC1D9B 5
- USP6NL 5
- TBC1D8B 5
- TBC1D4 5
- SGSM3 5
- TBC1D1 5
- EVI5L 5
- RABGAP1 5
- EVI5 5
- TBC1D2 5
- TBC1D30 5
- RABGAP1L 5
- GRTP1 5
- TBC1D3B 5
- TBC1D3I 5
- TBC1D3G 5
- TBC1D3H 5
- TBC1D3F 5
- TBCK 5
- TBC1D3K 5
- TBC1D3L 5
- TBC1D3D 5
- TBC1D3C 5
- TBC1D3E 5
- TBC1D3 5
- TBC1D2B 5
- ENSG00000288591 5
- TBC1D15 5
- TBC1D17 5
- SGSM1 5
- TBC1D14 5
- TBC1D5 5
- TBC1D12 5
- TBC1D25 5
- SGSM2 5
- TBC1D22A 5
- TBC1D22B 5
- TBC1D16 5
- TBC1D21 5
- TBC1D13 5
- TBC1D26 5
- TBC1D28 5
(13) SIMAP similar genes for TBC1D10A Gene using alignment to 7 proteins:
- TB10A_HUMAN
- A7E244_HUMAN
- B5MD46_HUMAN
- B7ZVY9_HUMAN
- F8W9Y7_HUMAN
- F8WCD1_HUMAN
- F8WDN6_HUMAN
Variants for TBC1D10A Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TBC1D10A Gene
| SNP ID | Clinical significance and condition | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs4823086 | - |
p.Arg411His |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
48.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.53;
64.75% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TBC1D10A Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TBC1D10A
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TBC1D10A Gene
Disorders for TBC1D10A Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hyperhidrosis, gustatory |
|
|
Search TBC1D10A in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TBC1D10A
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for TBC1D10A Gene
Publications for TBC1D10A Gene
- Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP. (PMID: 11285285) Reczek D … Bretscher A (The Journal of cell biology 2001) 2 3 4
- Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. (PMID: 20404108) Hsu C … Simons M (The Journal of cell biology 2010) 2 3
- Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. (PMID: 19077034) Ishibashi K … Fukuda M (Genes to cells : devoted to molecular & cellular mechanisms 2009) 3 4
- Identification of EPI64 as a GTPase-activating protein specific for Rab27A. (PMID: 16923811) Itoh T … Fukuda M (The Journal of biological chemistry 2006) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
ExternalLinks
Products for TBC1D10A Gene
- Custom Antibody ServicesOriGene Antibodies for TBC1D10A
- Browse OriGene ELISA Kits
- Custom Assay Services
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- Origene Custom Protein Services for TBC1D10A
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TBC1D10A
- Browse OriGene Inhibitory RNA Products For TBC1D10A
- OriGene qPCR primer pairs for TBC1D10A
- OriGene qPCR primer pairs and template standards for TBC1D10A
- OriGene CRISPR knockouts for TBC1D10A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TBC1D10A
- Sino Biological Human cDNA Clone for TBC1D10A
- Browse Sino Biological Recombinant Proteins
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- High-throughput Antibody Production Service
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- Browse Antibodies
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- Invitrogen Antibodies for TBC1D10A (AFLGC-TBC1D10A)
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- VectorBuilder CRISPR vectors for TBC1D10A (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TBC1D10A CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TBC1D10A
- antibodies-online: Show 15 available TBC1D10A Antibodies ranked by validation data
- Compare Top TBC1D10A Antibodies
- antibodies-online: Search results for available TBC1D10A related products ranked by validation data
- antibodies-online: Show 3 available TBC1D10A Proteins ranked by validation data
- Compare Top TBC1D10A Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for TBC1D10A
- Search Santa Cruz Biotechnology (SCBT) for TBC1D10A siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TBC1D10A
- Custom Antibody ServicesProSci Antibodies for TBC1D10A
- Search for TBC1D10A Proteins at ProSci
- Horizon Cell Lines for TBC1D10A
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TBC1D10A
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TBC1D10A
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TBC1D10A
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TBC1D10A
- Biorbyt antibodies for TBC1D10A
Sources for TBC1D10A Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB