Aliases for TAS2R40 Gene
External Ids for TAS2R40 Gene
Previous HGNC Symbols for TAS2R40 Gene
Previous GeneCards Identifiers for TAS2R40 Gene
This gene encodes a member of the bitter taste receptor family which belong to the G protein-coupled receptor superfamily and are predominantly expressed in taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a seven-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered together with eight other taste receptor genes on chromosome 7. A decrease in the expression of this gene is associated with hypogeusia. [provided by RefSeq, Jul 2017]
GeneCards Summary for TAS2R40 Gene
TAS2R40 (Taste 2 Receptor Member 40) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Taste transduction. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and bitter taste receptor activity. An important paralog of this gene is TAS2R39.
UniProtKB/Swiss-Prot for TAS2R40 Gene
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.