Aliases for TAS2R20 Gene
External Ids for TAS2R20 Gene
Previous HGNC Symbols for TAS2R20 Gene
Previous GeneCards Identifiers for TAS2R20 Gene
This gene encodes a member of the taste receptor two family of class C G-protein coupled receptors. Receptors of this family have a short extracellular N-terminus, seven transmembrane helices, three extracellular loops and three intracellular loops, and an intracellular C-terminus. Members of this family are expressed in a subset of taste receptor cells, where they function in bitter taste reception, as well as in non-gustatory cells including those of the brain, reproductive organs, respiratory system, and gastrointestinal system. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2016]
GeneCards Summary for TAS2R20 Gene
TAS2R20 (Taste 2 Receptor Member 20) is a Protein Coding gene. Diseases associated with TAS2R20 include Fructose Intolerance, Hereditary. Among its related pathways are Signaling by GPCR and Taste transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is TAS2R46.
UniProtKB/Swiss-Prot Summary for TAS2R20 Gene
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).