Aliases for TAS1R3 Gene
External Ids for TAS1R3 Gene
Previous GeneCards Identifiers for TAS1R3 Gene
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015]
GeneCards Summary for TAS1R3 Gene
TAS1R3 (Taste 1 Receptor Member 3) is a Protein Coding gene. Diseases associated with TAS1R3 include Dental Caries and Kagami-Ogata Syndrome. Among its related pathways are Signaling by GPCR and Taste transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and taste receptor activity. An important paralog of this gene is TAS1R1.
UniProtKB/Swiss-Prot Summary for TAS1R3 Gene
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.