Aliases for TAS1R1 Gene
External Ids for TAS1R1 Gene
Previous HGNC Symbols for TAS1R1 Gene
Previous GeneCards Identifiers for TAS1R1 Gene
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
GeneCards Summary for TAS1R1 Gene
TAS1R1 (Taste 1 Receptor Member 1) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Taste transduction. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and taste receptor activity. An important paralog of this gene is TAS1R2.
UniProtKB/Swiss-Prot for TAS1R1 Gene
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.