Aliases for TARM1 Gene
External Ids for TARM1 Gene
Previous GeneCards Identifiers for TARM1 Gene
GeneCards Summary for TARM1 Gene
TARM1 (T Cell-Interacting, Activating Receptor On Myeloid Cells 1) is a Protein Coding gene. Diseases associated with TARM1 include Retinitis Pigmentosa. Among its related pathways are Innate Immune System. An important paralog of this gene is IGSF1.
UniProtKB/Swiss-Prot Summary for TARM1 Gene
May act as receptor (By similarity). Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface (PubMed:26311901). Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity).