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Aliases for TAOK2 Gene

Aliases for TAOK2 Gene

  • TAO Kinase 2 2 3 5
  • Thousand And One Amino Acid Protein Kinase 2 3 4
  • Prostate-Derived Sterile 20-Like Kinase 1 3 4
  • Prostate-Derived STE20-Like Kinase 1 3 4
  • Kinase From Chicken Homolog C 3 4
  • EC 2.7.11.1 4 56
  • MAP3K17 3 4
  • HKFC-C 3 4
  • PSK-1 3 4
  • PSK1 3 4
  • PSK 3 4
  • Prostate Derived STE20-Like Kinase PSK 3
  • Serine/Threonine-Protein Kinase TAO2 3
  • PSK1-BETA 3
  • EC 2.7.11 56
  • KIAA0881 4
  • TAO1 3
  • TAO2 3

External Ids for TAOK2 Gene

Previous GeneCards Identifiers for TAOK2 Gene

  • GC16P029892
  • GC16P027646

Summaries for TAOK2 Gene

Entrez Gene Summary for TAOK2 Gene

  • This gene encodes a serine/threonine protein kinase that is involved in many different processes, including, cell signaling, microtubule organization and stability, and apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

GeneCards Summary for TAOK2 Gene

TAOK2 (TAO Kinase 2) is a Protein Coding gene. Among its related pathways are MAPK signaling pathway and p38 MAPK signaling pathway (Pathway Interaction Database). Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is TAOK1.

UniProtKB/Swiss-Prot for TAOK2 Gene

  • Serine/threonine-protein kinase involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 MAPK stress-activated MAPK cascade. Phosphorylates itself, MBP, activated MAPK8, MAP2K3, MAP2K6 and tubulins. Activates the MAPK14/p38 MAPK signaling pathway through the specific activation and phosphorylation of the upstream MAP2K3 and MAP2K6 kinases. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Isoform 1, but not isoform 2, plays a role in apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation. This function, which requires the activation of MAPK8/JNK and nuclear localization of C-terminally truncated isoform 1, may be linked to the mitochondrial CASP9-associated death pathway. Isoform 1 binds to microtubules and affects their organization and stability independently of its kinase activity. Prevents MAP3K7-mediated activation of CHUK, and thus NF-kappa-B activation, but not that of MAPK8/JNK. May play a role in the osmotic stress-MAPK8 pathway. Isoform 2, but not isoform 1, is required for PCDH8 endocytosis. Following homophilic interactions between PCDH8 extracellular domains, isoform 2 phosphorylates and activates MAPK14/p38 MAPK which in turn phosphorylates isoform 2. This process leads to PCDH8 endocytosis and CDH2 cointernalization. Both isoforms are involved in MAPK14 phosphorylation.

Gene Wiki entry for TAOK2 Gene

Additional gene information for TAOK2 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TAOK2 Gene

Genomics for TAOK2 Gene

GeneHancer (GH) Regulatory Elements for TAOK2 Gene

Promoters and enhancers for TAOK2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I029972 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE 561.4 +1.9 1916 6.1 HDGF PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 TAOK2 SETD1A INO80E NPIPB12 SRCAP NPIPB13 ENSG00000260367 ZNF764 ZNF785 BCL7C
GH16I030697 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 40 +725.5 725494 3.8 CLOCK MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 SRCAP LOC730183 ZNF785 FUS SETD1A TAOK2 ENSG00000260267 ENSG00000260114 BCL7C SMG1P5
GH16I030566 Promoter/Enhancer 2.3 FANTOM5 Ensembl ENCODE dbSUPER 30.5 +596.2 596233 6 ZFP64 FEZF1 DMAP1 YY1 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 SP3 SETD1A SRCAP ENSG00000260267 FUS INO80E ZNF747 NPIPB13 ZNF764 SMG1P5 SMG1P2
GH16I030555 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 29.9 +584.4 584430 4.2 ZFP64 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF548 SP3 NFYC ZNF764 ENSG00000260869 FUS SETD1A ZNF785 SRCAP ENSG00000260114 TAOK2 INO80E SMG1P2
GH16I029898 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 27.2 -73.1 -73093 3.8 PKNOX1 ARNT MLX ZFP64 ARID4B SIN3A YBX1 FEZF1 DMAP1 ZNF2 ASPHD1 GC16M029899 GC16M029900 SEZ6L2 ZNF785 ENSG00000260114 SMG1P5 SMG1P2 SRCAP MIR762HG
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TAOK2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TAOK2 gene promoter:

Genomic Locations for TAOK2 Gene

Genomic Locations for TAOK2 Gene
chr16:29,973,641-29,992,261
(GRCh38/hg38)
Size:
18,621 bases
Orientation:
Plus strand
chr16:29,984,962-30,003,582
(GRCh37/hg19)

Genomic View for TAOK2 Gene

Genes around TAOK2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TAOK2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TAOK2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TAOK2 Gene

Proteins for TAOK2 Gene

  • Protein details for TAOK2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UL54-TAOK2_HUMAN
    Recommended name:
    Serine/threonine-protein kinase TAO2
    Protein Accession:
    Q9UL54
    Secondary Accessions:
    • A5PKY1
    • A7MCZ2
    • B2RN35
    • B7ZM88
    • O94957
    • Q6UW73
    • Q7LC09
    • Q9NSW2

    Protein attributes for TAOK2 Gene

    Size:
    1235 amino acids
    Molecular mass:
    138251 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    • Interacts with MAP2K3 and MAP2K6 (By similarity). Self-associates. Interacts with tubulins through the C-terminal domain. Interacts with MAP3K7 and interfers with MAP3K7-binding to CHUK and thus prevents NF-kappa-B activation. Isoform 2 interacts with PCDH8; this complex may also include CDH2 (By similarity).
    SequenceCaution:
    • Sequence=AAQ89301.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAA74904.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for TAOK2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TAOK2 Gene

Selected DME Specific Peptides for TAOK2 Gene

Q9UL54:
  • KKMSYSGKQ
  • LQHQTEL
  • DLIQRTKDAVRELDNLQYRKMKKILFQE
  • THGALQGLAYLHSH
  • ARRRAYCRNRDHFATIRTASLV
  • RAGSLKDPDVAELFF
  • QEHEQDS
  • STPKREK
  • FVLRERP
  • EIGHGSFGAVYFA
  • FLQKLRHPNTI
  • EMAMMQEGEHTVTS
  • KFQQHILGQQKKEL
  • YDGKVDV
  • EKWQDIIKEV
  • WSLGITCIELAER
  • RKEQLKEEL
  • QTQKDLE
  • EARAAQAE
  • SVPSMSISASSQSSSVNSLADASD
  • KAGNILL
  • LLRRQRQYFELQCRQYKRKMLLARH
  • LDQDLLRE
  • LFFKDDPE
  • MNAMSALYHIAQN
  • EWLLRQKE
  • SGYKRMRRQHQKQL
  • WMAPEVI
  • HWSEYFRNFVDSCLQKIPQDRPTS
  • GTPYWMAPE
  • NQLEYNKRRE

Post-translational modifications for TAOK2 Gene

  • Autophosphorylated. Phosphorylated by ATM.
  • C-terminal cleavage of isoform 1 and subsequent nuclear localization requires CASP9 activity.
  • Isoform 2: Phosphorylated on Ser-1031 by MAPK14. This phosphorylation is required PCDH8 for endocytosis (By similarity).
  • Isoforms 1 and 2 are autophosphorylated.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Domains & Families for TAOK2 Gene

Gene Families for TAOK2 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins
  • Predicted membrane proteins

Suggested Antigen Peptide Sequences for TAOK2 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UL54

UniProtKB/Swiss-Prot:

TAOK2_HUMAN :
  • Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Family:
  • Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
genes like me logo Genes that share domains with TAOK2: view

Function for TAOK2 Gene

Molecular function for TAOK2 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
ATP + a protein = ADP + a phosphoprotein.
UniProtKB/Swiss-Prot EnzymeRegulation:
Selectively inhibited by the enantiopure organoruthenium inhibitor 9E1. Activated following arsenic trioxide (As(2)O(3)) treatment.
UniProtKB/Swiss-Prot Function:
Serine/threonine-protein kinase involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 MAPK stress-activated MAPK cascade. Phosphorylates itself, MBP, activated MAPK8, MAP2K3, MAP2K6 and tubulins. Activates the MAPK14/p38 MAPK signaling pathway through the specific activation and phosphorylation of the upstream MAP2K3 and MAP2K6 kinases. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Isoform 1, but not isoform 2, plays a role in apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation. This function, which requires the activation of MAPK8/JNK and nuclear localization of C-terminally truncated isoform 1, may be linked to the mitochondrial CASP9-associated death pathway. Isoform 1 binds to microtubules and affects their organization and stability independently of its kinase activity. Prevents MAP3K7-mediated activation of CHUK, and thus NF-kappa-B activation, but not that of MAPK8/JNK. May play a role in the osmotic stress-MAPK8 pathway. Isoform 2, but not isoform 1, is required for PCDH8 endocytosis. Following homophilic interactions between PCDH8 extracellular domains, isoform 2 phosphorylates and activates MAPK14/p38 MAPK which in turn phosphorylates isoform 2. This process leads to PCDH8 endocytosis and CDH2 cointernalization. Both isoforms are involved in MAPK14 phosphorylation.

Enzyme Numbers (IUBMB) for TAOK2 Gene

Phenotypes From GWAS Catalog for TAOK2 Gene

Gene Ontology (GO) - Molecular Function for TAOK2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity IEA --
GO:0004674 protein serine/threonine kinase activity IEA,NAS 22683681
GO:0004709 MAP kinase kinase kinase activity IBA,NAS 22683681
GO:0005524 ATP binding IEA --
GO:0016301 kinase activity IEA --
genes like me logo Genes that share ontologies with TAOK2: view
genes like me logo Genes that share phenotypes with TAOK2: view

Animal Models for TAOK2 Gene

MGI Knock Outs for TAOK2:

Animal Model Products

  • Taconic Biosciences Mouse Models for TAOK2

CRISPR Products

miRNA for TAOK2 Gene

Inhibitory RNA Products

Clone Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TAOK2 Gene

Localization for TAOK2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TAOK2 Gene

Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Nucleus. Note=Catalytically active full-length phosphorylated isoform 1 localizes to microtubules in the cytoplasm predominantly on microtubule cables positioned around the nucleus. A C-terminally truncated form of isoform 1 is present in the nucleus; isoform 2 and kinase-defective, as well as full-length isoform 1 are excluded from the nucleus.
Isoform 2: Cell projection, dendrite. Note=In dendrites, colocalizes with PCDH8. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TAOK2 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 5
plasma membrane 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (3)
  • Nucleus (3)
  • Cytosol (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for TAOK2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IDA --
GO:0005856 cytoskeleton IEA --
genes like me logo Genes that share ontologies with TAOK2: view

Pathways & Interactions for TAOK2 Gene

genes like me logo Genes that share pathways with TAOK2: view

Pathways by source for TAOK2 Gene

2 BioSystems pathways for TAOK2 Gene
1 KEGG pathway for TAOK2 Gene

SIGNOR curated interactions for TAOK2 Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for TAOK2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000186 activation of MAPKK activity IDA 10660600
GO:0000187 activation of MAPK activity TAS 22683681
GO:0001558 regulation of cell growth NAS 10660600
GO:0006468 protein phosphorylation IEA --
GO:0006612 protein targeting to membrane NAS 10660600
genes like me logo Genes that share ontologies with TAOK2: view

Drugs & Compounds for TAOK2 Gene

(4) Drugs for TAOK2 Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Magnesium Approved Nutra 0
phosphoserine Experimental Pharma Target 0
ATP Investigational Nutra Agonist 0

(1) Additional Compounds for TAOK2 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
genes like me logo Genes that share compounds with TAOK2: view

Transcripts for TAOK2 Gene

Unigene Clusters for TAOK2 Gene

TAO kinase 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TAOK2 Gene

No ASD Table

Relevant External Links for TAOK2 Gene

GeneLoc Exon Structure for
TAOK2
ECgene alternative splicing isoforms for
TAOK2

Expression for TAOK2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TAOK2 Gene

Protein differential expression in normal tissues from HIPED for TAOK2 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (21.3), Urine (10.7), and Heart (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TAOK2 Gene



NURSA nuclear receptor signaling pathways regulating expression of TAOK2 Gene:

TAOK2

SOURCE GeneReport for Unigene cluster for TAOK2 Gene:

Hs.291623

mRNA Expression by UniProt/SwissProt for TAOK2 Gene:

Q9UL54-TAOK2_HUMAN
Tissue specificity: Ubiquitously expressed, with a higher level of expression in testis and brain.

Evidence on tissue expression from TISSUES for TAOK2 Gene

  • Nervous system(4.6)
  • Liver(4.2)
genes like me logo Genes that share expression patterns with TAOK2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for TAOK2 Gene

Orthologs for TAOK2 Gene

This gene was present in the common ancestor of animals.

Orthologs for TAOK2 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia TAOK2 34
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TAOK2 34
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TAOK2 33 34
  • 93.2 (n)
mouse
(Mus musculus)
Mammalia Taok2 33 16 34
  • 90.1 (n)
chimpanzee
(Pan troglodytes)
Mammalia TAOK2 34
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TAOK2 34
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TAOK2 34
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia taok2 33
  • 75.25 (n)
zebrafish
(Danio rerio)
Actinopterygii taok2b 33 34 34
  • 72.65 (n)
taok2a 34
  • 56 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Tao 34
  • 39 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea kin-18 34
  • 33 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 29 (a)
OneToMany
Species where no ortholog for TAOK2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TAOK2 Gene

ENSEMBL:
Gene Tree for TAOK2 (if available)
TreeFam:
Gene Tree for TAOK2 (if available)

Paralogs for TAOK2 Gene

Paralogs for TAOK2 Gene

genes like me logo Genes that share paralogs with TAOK2: view

Variants for TAOK2 Gene

Sequence variations from dbSNP and Humsavar for TAOK2 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000137586 -- 29,981,830(+) C/G intron_variant
rs1000300527 -- 29,975,312(+) G/A intron_variant
rs1000554434 -- 29,977,102(+) G/T intron_variant
rs1000650947 -- 29,975,104(+) G/A/T intron_variant
rs1000767856 -- 29,988,138(+) CCTCCTC/CCTC 3_prime_UTR_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TAOK2 Gene

Variant ID Type Subtype PubMed ID
esv3638378 CNV loss 21293372
esv997840 CNV deletion 20482838

Variation tolerance for TAOK2 Gene

Residual Variation Intolerance Score: 1.52% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.36; 41.90% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TAOK2 Gene

Human Gene Mutation Database (HGMD)
TAOK2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TAOK2

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TAOK2 Gene

Disorders for TAOK2 Gene

Additional Disease Information for TAOK2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for TAOK2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TAOK2 Gene

Publications for TAOK2 Gene

  1. The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability. (PMID: 12639963) Mitsopoulos C … Morris JD (The Journal of biological chemistry 2003) 3 4 22 58
  2. PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization. (PMID: 10660600) Moore TM … Morris JD (The Journal of biological chemistry 2000) 3 4 22 58
  3. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10048485) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 2 3 4 58
  4. Association and mutation analyses of 16p11.2 autism candidate genes. (PMID: 19242545) Kumar RA … Christian SL (PloS one 2009) 3 44 58
  5. TAO kinases mediate activation of p38 in response to DNA damage. (PMID: 17396146) Raman M … Cobb MH (The EMBO journal 2007) 3 4 58

Products for TAOK2 Gene

Sources for TAOK2 Gene

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