Aliases for TAFA3 Gene
External Ids for TAFA3 Gene
Previous HGNC Symbols for TAFA3 Gene
Previous GeneCards Identifiers for TAFA3 Gene
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
GeneCards Summary for TAFA3 Gene
TAFA3 (TAFA Chemokine Like Family Member 3) is a Protein Coding gene. An important paralog of this gene is TAFA4.
UniProtKB/Swiss-Prot Summary for TAFA3 Gene
Plays a role in the regulation of microglia polarization.