Aliases for TAF7 Gene
- TATA-Box Binding Protein Associated Factor 7 2 3 5
- TAFII55 2 3 4
- TAF7 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 55kDa 2 3
- TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, F, 55kD 2 3
- RNA Polymerase II TBP-Associated Factor Subunit F 3 4
- Transcription Initiation Factor TFIID Subunit 7 3 4
- TAF(II)55 3 4
External Ids for TAF7 Gene
Previous HGNC Symbols for TAF7 Gene
Previous GeneCards Identifiers for TAF7 Gene
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. [provided by RefSeq, Jul 2008]
GeneCards Summary for TAF7 Gene
TAF7 (TATA-Box Binding Protein Associated Factor 7) is a Protein Coding gene. Diseases associated with TAF7 include Branchiootorenal Syndrome 2 and Splenic Manifestation Of Leukemia. Among its related pathways are RNA Polymerase II Transcription Initiation And Promoter Clearance and Regulation of TP53 Activity. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and transcription coactivator activity. An important paralog of this gene is TAF7L.
UniProtKB/Swiss-Prot Summary for TAF7 Gene
Functions as a component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively).