Aliases for TAF13 Gene
Aliases for TAF13 Gene
- TATA-Box Binding Protein Associated Factor 13 2 3 5
- TAF13 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 18kDa 2 3
- TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, K, 18kD 2 3
- Transcription Initiation Factor TFIID 18 KDa Subunit 3 4
- TAF(II)18 3 4
- TAFII-18 3 4
External Ids for TAF13 Gene
- HGNC: 11546
- Entrez Gene: 6884
- Ensembl: ENSG00000197780
- OMIM: 600774
- UniProtKB: Q15543
Previous HGNC Symbols for TAF13 Gene
- TAF2K
Previous GeneCards Identifiers for TAF13 Gene
- GC01M110076
- GC01M9C0097
- GC01U900282
- GC00M9T0035
- GC01M109318
- GC01M109406
- GC01M109605
- GC01M107499
Summaries for TAF13 Gene
-
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008]
GeneCards Summary for TAF13 Gene
TAF13 (TATA-Box Binding Protein Associated Factor 13) is a Protein Coding gene. Diseases associated with TAF13 include Mental Retardation, Autosomal Recessive 60 and Microcephaly. Among its related pathways are Gene Expression and RNA Polymerase II Transcription Initiation And Promoter Clearance. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and protein C-terminus binding.
UniProtKB/Swiss-Prot for TAF13 Gene
-
Component of the DNA-binding general RNA polymerase II transcription factor IID complex (TFIID). TFIID plays a critical role in the regulation of gene transcription in eukaryotic cells.
Additional gene information for TAF13 Gene
- Monarch Initiative
- Search for TAF13 at DataMed
- Search for TAF13 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TAF13 Gene
Genomics for TAF13 Gene
GeneHancer (GH) Regulatory Elements for TAF13 Gene
Promoters and enhancers for TAF13 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around TAF13 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the TAF13 gene promoter:
Regulatory Element Products
Genomic Locations for TAF13 Gene
Genomic Locations for TAF13 Gene
- chr1:109,062,486-109,076,002
- (GRCh38/hg38)
- Size:
- 13,517 bases
- Orientation:
- Minus strand
- chr1:109,605,108-109,618,624
- (GRCh37/hg19)
Genomic View for TAF13 Gene
Genes around TAF13 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p13.3 by Entrez Gene
- 1p13.3 by HGNC
- 1p13.3 by Ensembl
TAF13 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TAF13 Gene
Proteins for TAF13 Gene
-
Protein details for TAF13 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q15543-TAF13_HUMAN
- Recommended name:
- Transcription initiation factor TFIID subunit 13
- Protein Accession:
- Q15543
- B2R5E5
- Q5TYV6
Protein attributes for TAF13 Gene
- Size:
- 124 amino acids
- Molecular mass:
- 14287 Da
- Quaternary structure:
-
- TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Interacts with TBP, and more strongly with TAF10 and TAF11.
Protein Expression for TAF13 Gene
Post-translational modifications for TAF13 Gene
Other Protein References for TAF13 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for TAF13
- Invitrogen Antibodies for TAF13
- GeneTex TAF13 Antibody for TAF13
-
Boster Bio Antibodies for TAF13
-
Santa Cruz Biotechnology (SCBT) Antibodies for TAF13
Protein Products
-
OriGene Purified Proteins for TAF13
- Search Origene for MassSpec and Protein Over-expression Lysates for TAF13
- Origene Custom Protein Services for TAF13
- antibodies-online: Search results for 8 available TAF13 Proteins ranked by validation data
- Compare Top TAF13 Proteins
-
Quality Products:
- Search GeneTex for Proteins for TAF13
Assay Products
- antibodies-online: Search results for 3 available TAF13 Elisa Kits ranked by validation data
- Compare Top TAF13 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for TAF13 Gene
Domains & Families for TAF13 Gene
Gene Families for TAF13 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for TAF13 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TAF13 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q15543UniProtKB/Swiss-Prot:
TAF13_HUMAN :- The binding of TAF10 and TAF11 requires distinct domains of TAF13.
- Belongs to the TAF13 family.
- Domain:
-
- The binding of TAF10 and TAF11 requires distinct domains of TAF13.
- Family:
-
- Belongs to the TAF13 family.
Function for TAF13 Gene
Molecular function for TAF13 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the DNA-binding general RNA polymerase II transcription factor IID complex (TFIID). TFIID plays a critical role in the regulation of gene transcription in eukaryotic cells.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IBA | -- |
| GO:0003700 | DNA binding transcription factor activity | NAS | 9695952 |
| GO:0003712 | transcription coregulator activity | IBA | -- |
| GO:0005515 | protein binding | IPI | 7729427 |
| GO:0008022 | protein C-terminus binding | IPI | 7729427 |
Phenotypes for TAF13 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TAF13
-
CRISPR Products
-
OriGene CRISPR knockouts for TAF13
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TAF13
- genomics-online: gRNA clones - Search results for 91 available TAF13 gene related products
- Overview of 91 available TAF13 gene related products
- Applied Biological Materials CRISPR for TAF13
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TAF13
- GenScript: Design CRISPR guide RNA sequences for TAF13
miRNA for TAF13 Gene
- miRTarBase miRNAs that target TAF13
-
- hsa-mir-4465 (MIRT466686)
- hsa-mir-26b-5p (MIRT466687)
- hsa-mir-26a-5p (MIRT466688)
- hsa-mir-1297 (MIRT466689)
- hsa-mir-5697 (MIRT466690)
- hsa-mir-5579-5p (MIRT466691)
- hsa-mir-5590-3p (MIRT466692)
- hsa-mir-142-5p (MIRT466693)
- hsa-mir-940 (MIRT466694)
- hsa-mir-6893-5p (MIRT466695)
- hsa-mir-6808-5p (MIRT466696)
- hsa-mir-4482-5p (MIRT466697)
- hsa-mir-3130-5p (MIRT466698)
- hsa-mir-4760-3p (MIRT466699)
- hsa-mir-1277-5p (MIRT466700)
- hsa-mir-3714 (MIRT466701)
- hsa-mir-4484 (MIRT466702)
- hsa-mir-6768-3p (MIRT466703)
- hsa-mir-548an (MIRT466704)
- hsa-mir-548as-3p (MIRT466705)
- hsa-mir-340-5p (MIRT466706)
- hsa-mir-6792-5p (MIRT553765)
- hsa-mir-5689 (MIRT553766)
- hsa-mir-107 (MIRT553767)
- hsa-mir-103a-3p (MIRT553768)
- hsa-mir-6838-5p (MIRT553769)
- hsa-mir-96-3p (MIRT553770)
- hsa-mir-497-5p (MIRT553771)
- hsa-mir-424-5p (MIRT553772)
- hsa-mir-195-5p (MIRT553773)
- hsa-mir-16-5p (MIRT553774)
- hsa-mir-15b-5p (MIRT553775)
- hsa-mir-5694 (MIRT553776)
- hsa-mir-15a-5p (MIRT553777)
- hsa-mir-383-5p (MIRT553778)
- hsa-mir-548at-5p (MIRT553779)
- hsa-mir-548ay-3p (MIRT553780)
- hsa-mir-548at-3p (MIRT553781)
- hsa-mir-548t-3p (MIRT553782)
- hsa-mir-548ap-3p (MIRT553783)
- hsa-mir-548aa (MIRT553784)
- hsa-mir-6720-5p (MIRT621890)
- hsa-mir-6512-3p (MIRT621891)
- hsa-mir-921 (MIRT621892)
- hsa-mir-4763-5p (MIRT621893)
- hsa-mir-5189-3p (MIRT621894)
- hsa-mir-766-3p (MIRT621895)
- hsa-mir-6727-3p (MIRT621896)
- hsa-mir-4722-3p (MIRT621897)
- hsa-mir-6849-3p (MIRT621898)
- hsa-mir-3174 (MIRT621899)
- hsa-mir-596 (MIRT621900)
- hsa-mir-508-5p (MIRT621901)
- hsa-mir-7703 (MIRT638199)
- hsa-mir-4252 (MIRT638200)
- hsa-mir-4793-3p (MIRT638201)
- hsa-mir-1273g-3p (MIRT638202)
- hsa-mir-101-3p (MIRT761079)
- hsa-mir-139-5p (MIRT762613)
- hsa-mir-144-3p (MIRT762714)
- hsa-mir-3613-3p (MIRT766004)
- hsa-mir-4668-5p (MIRT770868)
- hsa-mir-548v (MIRT774551)
- hsa-mir-7705 (MIRT782094)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TAF13
- Browse OriGene Inhibitory RNA Products For TAF13
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TAF13
- genomics-online: shRNA clones - Search results for 91 available TAF13 gene related products
- Overview of 91 available TAF13 gene related products
Clone Products
- Sino Biological Human cDNA Clone for TAF13
- VectorBuilder custom plasmid, inducible vectors for TAF13
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TAF13
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TAF13
- Applied Biological Materials Clones for TAF13
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for TAF13
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Animal Models , Transcription Factor Targets and HOMER Transcription for TAF13 Gene
Localization for TAF13 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TAF13 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| extracellular | 1 |
- Nucleoli (4)
- Nucleus (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005669 | transcription factor TFIID complex | NAS | 9695952 |
| GO:0005730 | nucleolus | IDA | -- |
Pathways & Interactions for TAF13 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RNA Polymerase II Transcription Initiation And Promoter Clearance | ||
| 2 | HIV Life Cycle |
.91
.64
|
.45
|
| 3 | Formation of HIV-1 elongation complex containing HIV-1 Tat | ||
| 4 | Regulation of TP53 Activity | ||
| 5 | Gene Expression |
.48
|
|
Pathways by source for TAF13 Gene
1 BioSystems pathway for TAF13 Gene
20 Reactome pathways for TAF13 Gene
2 KEGG pathways for TAF13 Gene
1 GeneGo (Thomson Reuters) pathway for TAF13 Gene
Interacting Proteins for TAF13 Gene
Selected Interacting proteins:
Q15543-TAF13_HUMAN
ENSP00000355051
for TAF13 Gene via
IID
UniProtKB
STRING
GPS-Prot Interaction Network for TAF13
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006352 | DNA-templated transcription, initiation | NAS | 9695952 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IBA | -- |
| GO:0006366 | transcription by RNA polymerase II | TAS | -- |
No data available for SIGNOR curated interactions for TAF13 Gene
Transcripts for TAF13 Gene
mRNA/cDNA for TAF13 Gene
- (73) Selected AceView cDNA sequences:
- (4) Additional mRNA sequences :
- (1) REFSEQ mRNAs :
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000338366 813 bps (uc001dwm.2)
- ENST00000461096 1076 bps (uc057ixe.1)
Unigene Clusters for TAF13 Gene
- TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for TAF13
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TAF13
- genomics-online: gRNA clones - Search results for 91 available TAF13 gene related products
- Overview of 91 available TAF13 gene related products
- Applied Biological Materials CRISPR for TAF13
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TAF13
- GenScript: Design CRISPR guide RNA sequences for TAF13
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TAF13
- Browse OriGene Inhibitory RNA Products For TAF13
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TAF13
- genomics-online: shRNA clones - Search results for 91 available TAF13 gene related products
- Overview of 91 available TAF13 gene related products
Clone Products
- Sino Biological Human cDNA Clone for TAF13
- VectorBuilder custom plasmid, inducible vectors for TAF13
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TAF13
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TAF13
- Applied Biological Materials Clones for TAF13
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for TAF13 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
This gene is overexpressed in Fetal Brain (39.3) and Placenta (29.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TAF13 Gene
NURSA nuclear receptor signaling pathways regulating expression of TAF13 Gene:
TAF13SOURCE GeneReport for Unigene cluster for TAF13 Gene:
Hs.632426Evidence on tissue expression from TISSUES for TAF13 Gene
- Nervous system(4.4)
- Liver(2)
Primer Products
-
OriGene qPCR primer pairs for TAF13
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TAF13 Gene
Orthologs for TAF13 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TAF13 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | TAF13 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | TAF13 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | TAF13 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Taf13 16 34 33 |
|
||
| chicken (Gallus gallus) |
Aves | TAF13 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | TAF13 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | taf13 33 |
|
||
| Str.6597 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.4615 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | taf13 34 33 |
|
OneToOne | |
| wufc20d03 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.1879 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Taf13 34 35 33 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP008045 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | taf-13 34 33 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | TAF13 36 34 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | TAF13 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5080 34 |
|
OneToOne | |
| Cin.4198 33 |
|
||||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.4198 33 |
|
- Species where no ortholog for TAF13 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for TAF13 Gene
- ENSEMBL:
- Gene Tree for TAF13 (if available)
- TreeFam:
- Gene Tree for TAF13 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TAF13: view image
Paralogs for TAF13 Gene
(1) SIMAP similar genes for TAF13 Gene using alignment to 2 proteins:
- TAF13_HUMAN
- Q0VA92_HUMAN
Pseudogenes.org Pseudogenes for TAF13 Gene
No data available for Paralogs for TAF13 Gene
Variants for TAF13 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1060505029 | pathogenic, Mental retardation, autosomal recessive 60, not provided | 109,066,220(-) | A/T | coding_sequence_variant, missense_variant | |
| rs1060505030 | pathogenic, Mental retardation, autosomal recessive 60, not provided | 109,075,001(-) | A/G/T | coding_sequence_variant, missense_variant | |
| VAR_079046 | Mental retardation, autosomal recessive 60 (MRT60) [MIM:617432] | p.Leu31His | |||
| VAR_079047 | Mental retardation, autosomal recessive 60 (MRT60) [MIM:617432] | p.Met40Lys | |||
| rs1000070937 | -- | 109,076,050(-) | C/A/T | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2669667 | CNV | deletion | 23128226 |
| esv2715973 | CNV | deletion | 23290073 |
| esv2715984 | CNV | deletion | 23290073 |
| esv3587147 | CNV | loss | 21293372 |
| esv3894001 | CNV | gain | 25118596 |
| nsv1078062 | CNV | deletion | 25765185 |
| nsv1119707 | CNV | deletion | 24896259 |
| nsv831026 | CNV | loss | 17160897 |
| nsv954947 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
48.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.11;
2.45% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TAF13 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TAF13 Gene
Disorders for TAF13 Gene
(2) MalaCards diseases for TAF13 Gene - From: HGMD, OMIM, ClinVar, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| mental retardation, autosomal recessive 60 |
|
|
| microcephaly |
|
|
Search TAF13 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
TAF13_HUMAN- Mental retardation, autosomal recessive 60 (MRT60) [MIM:617432]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. In contrast to syndromic or specific mental retardation which also present with associated physical, neurological and/or psychiatric manifestations, intellectual deficiency is the only primary symptom of non-syndromic mental retardation. MRT60 patients display mild intellectual disability, delayed psychomotor development, learning difficulties, and poor overall growth with variable microcephaly. MRT60 inheritance is autosomal recessive. {ECO:0000269 PubMed:28257693}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for TAF13
No data available for Genatlas for TAF13 Gene
Publications for TAF13 Gene
- Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID. (PMID: 7729427) Mengus G … Davidson I (The EMBO journal 1995) 2 3 4 58
- Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly. (PMID: 28257693) Tawamie H … Abou Jamra R (American journal of human genetics 2017) 3 4 58
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family. (PMID: 9695952) Birck C … Moras D (Cell 1998) 3 4 58
Products for TAF13 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TAF13
- Search Origene for MassSpec and Protein Over-expression Lysates for TAF13
- Origene Custom Protein Services for TAF13
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TAF13
- Browse OriGene Inhibitory RNA Products For TAF13
- OriGene qPCR primer pairs for TAF13
- OriGene CRISPR knockouts for TAF13
- OriGene ORF clones in human for TAF13
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TAF13
- GenScript: Next-day shipping of latest version cDNA ORF clones for TAF13 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for TAF13
- GenScript Custom Assay Services for TAF13
- GenScript Custom overexpressing Cell Line Services for TAF13
- GenScript: Design CRISPR guide RNA sequences for TAF13
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for TAF13
- Sino Biological Human cDNA Clone for TAF13
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for TAF13
- Novus Biologicals lysates and proteins for TAF13
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder custom plasmid, inducible vectors for TAF13
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TAF13
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 29 available TAF13 Antibodies ranked by validation data
- Compare Top TAF13 Antibodies
- antibodies-online: Search results for 3 available TAF13 Elisa Kits ranked by validation data
- Compare Top TAF13 Elisa Kits
- Quality Products:
- antibodies-online: Search results for 8 available TAF13 Proteins ranked by validation data
- Compare Top TAF13 Proteins
- Quality Products:
- GeneTex TAF13 Antibody for TAF13
- Search GeneTex for Proteins for TAF13
- Santa Cruz Biotechnology (SCBT) Antibodies for TAF13
- Search Santa Cruz Biotechnology (SCBT) for TAF13 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TAF13
- Horizon Cell Lines for TAF13
- genomics-online: cdna clones - Search results for 91 available TAF13 gene related products
- Overview of 91 available TAF13 gene related products
- orf clones - Search results for 91 available TAF13 gene related products
- Overview of 91 available TAF13 gene related products
- genomics-online: gRNA clones - Search results for 91 available TAF13 gene related products
- Overview of 91 available TAF13 gene related products
- genomics-online: primer clones - Search results for 91 available TAF13 gene related products
- Overview of 91 available TAF13 gene related products
- genomics-online: shRNA clones - Search results for 91 available TAF13 gene related products
- Overview of 91 available TAF13 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TAF13
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TAF13
- GeneCopoeia miRNA 3'UTR Target clone products for TAF13
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TAF13
- Boster Bio Antibodies for TAF13
- Browse Boster Bio ELISA Kits
Sources for TAF13 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio