Aliases for TADA2B Gene
External Ids for TADA2B Gene
Previous GeneCards Identifiers for TADA2B Gene
TADA2B functions as a transcriptional adaptor protein that potentiates transcription through coordination of histone acetyltransferase (HAT) activity and by linking activation factors to basal transcriptional machinery (Barlev et al., 2003 [PubMed 12972612]).[supplied by OMIM, Apr 2010]
GeneCards Summary for TADA2B Gene
TADA2B (Transcriptional Adaptor 2B) is a Protein Coding gene. Diseases associated with TADA2B include Spinocerebellar Ataxia 7 and Amyotrophic Lateral Sclerosis 1. Among its related pathways are Deubiquitination and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include chromatin binding. An important paralog of this gene is TADA2A.
UniProtKB/Swiss-Prot Summary for TADA2B Gene
Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2.