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Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at ... See more...
Aliases for TADA2A Gene
Aliases for TADA2A Gene
External Ids for TADA2A Gene
- HGNC: 11531
- NCBI Entrez Gene: 6871
- Ensembl: ENSG00000276234
- OMIM®: 602276
- UniProtKB/Swiss-Prot: O75478
Previous HGNC Symbols for TADA2A Gene
- TADA2L
Previous GeneCards Identifiers for TADA2A Gene
- GC17P032842
- GC17P035767
- GC17P031705
Summaries for TADA2A Gene
-
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009]
GeneCards Summary for TADA2A Gene
TADA2A (Transcriptional Adaptor 2A) is a Protein Coding gene. Diseases associated with TADA2A include Chromosome 17Q12 Deletion Syndrome. Among its related pathways are Chromatin organization and RNA Polymerase II Transcription Initiation And Promoter Clearance. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and transcription coregulator activity. An important paralog of this gene is TADA2B.
UniProtKB/Swiss-Prot Summary for TADA2A Gene
-
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376).
Additional gene information for TADA2A Gene
- HGNC (11531)
- NCBI Entrez Gene (6871)
- Ensembl (ENSG00000276234)
- OMIM® (602276)
- UniProtKB/Swiss-Prot (O75478)
- Open Targets Platform(ENSG00000276234)
- Search for TADA2A at DataMed
- Search for TADA2A at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TADA2A Gene
Genomics for TADA2A Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TADA2A Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TADA2A on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TADA2A
Genomic Locations for TADA2A Gene
Latest Assembly
- chr17:37,406,877-37,479,725
- (GRCh38/hg38)
- Size:
- 72,849 bases
- Orientation:
- Plus strand
Previous Assembly
- chr17:35,766,977-35,839,830
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 72,854 bases
- Orientation:
- Plus strand
Genomic View for TADA2A Gene
Genes around TADA2A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q12 by HGNC
- 17q12 by Entrez Gene
- 17q12 by Ensembl
TADA2A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TADA2A Gene
Proteins for TADA2A Gene
-
Protein details for TADA2A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75478-TAD2A_HUMAN
- Recommended name:
- Transcriptional adapter 2-alpha
- Protein Accession:
- O75478
- A8MVD0
- B3KMU9
- Q9BVJ0
- Q9UCW2
- Q9UP49
Protein attributes for TADA2A Gene
- Size:
- 443 amino acids
- Molecular mass:
- 51506 Da
- Quaternary structure:
-
- Interacts with GCN5 and NR3C1. Associated with the P/CAF protein in the PCAF complex. Component of the PCAF complex, at least composed of TADA2L/ADA2, TADA3L/ADA3, TAF5L/PAF65-beta, TAF6L/PAF65-alpha, TAF10/TAFII30, TAF12/TAFII20, TAF9/TAFII31 and TRRAP. Component of the ADA2A-containing complex (ATAC), composed of KAT14, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. Interacts with CCDC134 (PubMed:22644376).
Protein Expression for TADA2A Gene
Post-translational modifications for TADA2A Gene
Other Protein References for TADA2A Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotag™ ADA2L Antibody
- Novus Biologicals Antibodies for TADA2A
- Invitrogen Antibodies for TADA2A (AFLGC-TADA2A)
-
Biorbyt antibodies for TADA2A
Protein products for research
-
OriGene Purified Proteins for TADA2A
- Search Origene for MassSpec and Protein Over-expression Lysates for TADA2A
- Origene Custom Protein Services for TADA2A
-
Abcam proteins for TADA2A
Assay products for research
-
Boster Bio ELISA Kits for TADA2A
No data available for DME Specific Peptides for TADA2A Gene
Domains & Families for TADA2A Gene
Gene Families for TADA2A Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for TADA2A Gene
- InterPro:
- Blocks:
-
- SWIRM
- Zn-finger, ZZ type
- ProtoNet:
Suggested Antigen Peptide Sequences for TADA2A Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ39052 fis, clone NT2RP7011721, highly similar to Transcriptional adapter 2 (B3KU13_HUMAN)
- Transcriptional adapter 2-like (TAD2A_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TADA2A Gene
Function for TADA2A Gene
Molecular function for TADA2A Gene
- UniProtKB/Swiss-Prot Function:
- Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376).
Phenotypes From GWAS Catalog for TADA2A Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003682 | chromatin binding | IBA | 21873635 |
| GO:0003713 | transcription coactivator activity | IEA,IBA | 21873635 |
| GO:0004402 | contributes_to histone acetyltransferase activity | IDA | 9674425 |
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for TADA2A Gene
- MGI mutant phenotypes for TADA2A:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TADA2A:
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TADA2A - Starting at $85 >
- * TADA2A CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TADA2A
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TADA2A
-
Santa Cruz Biotechnology (SCBT) CRISPR for TADA2A
miRNA for TADA2A Gene
- miRTarBase miRNAs that target TADA2A
-
- hsa-miR-5096 (MIRT533974)
- hsa-miR-197-3p (MIRT533976)
- hsa-miR-6832-5p (MIRT533977)
- hsa-miR-411-5p (MIRT533978)
- hsa-miR-873-3p (MIRT533979)
- hsa-miR-4716-5p (MIRT533980)
- hsa-miR-4676-3p (MIRT533981)
- hsa-miR-892c-3p (MIRT533982)
- hsa-miR-452-5p (MIRT533983)
- hsa-miR-4727-5p (MIRT644510)
- hsa-miR-6873-3p (MIRT644511)
- hsa-miR-4684-5p (MIRT644512)
- hsa-miR-942-5p (MIRT644513)
- hsa-miR-6817-5p (MIRT644514)
- hsa-miR-4769-3p (MIRT644515)
- hsa-miR-1236-3p (MIRT644516)
- hsa-miR-6515-3p (MIRT644517)
- hsa-miR-6817-3p (MIRT644518)
- hsa-miR-7110-3p (MIRT644519)
- hsa-miR-153-5p (MIRT644520)
- hsa-miR-487a-3p (MIRT644521)
- hsa-miR-154-3p (MIRT644522)
- hsa-miR-302f (MIRT644523)
- hsa-miR-4659b-3p (MIRT662362)
- hsa-miR-4659a-3p (MIRT662363)
- hsa-miR-6875-3p (MIRT662364)
- hsa-miR-3145-3p (MIRT662365)
- hsa-miR-6756-3p (MIRT662366)
- hsa-miR-3127-3p (MIRT662367)
- hsa-miR-541-5p (MIRT662368)
- hsa-miR-335-3p (MIRT709398)
- hsa-miR-511-5p (MIRT709399)
- hsa-miR-664b-3p (MIRT709400)
- hsa-miR-579-3p (MIRT709401)
- hsa-miR-5696 (MIRT709402)
- hsa-miR-4711-3p (MIRT709403)
- hsa-miR-6830-3p (MIRT709404)
- hsa-miR-6866-3p (MIRT709405)
- hsa-miR-188-5p (MIRT709406)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TADA2A
- Browse OriGene Inhibitory RNA Products For TADA2A
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TADA2A
Clone products for research
- Applied Biological Materials (abm): Clones for TADA2A - Starting at $45 >
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-
- MG207073
- MR207073
- MR207073L3
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- RC200580
- RC200580L3
- RC200580L4
- RC204042
- RC204042L3
- RC204042L4
- RC228898
- RC228898L3
- RC228898L4
- RC237330
- RG200580
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- RR201809
- RR201809L3
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- MR207073L3V
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- RC204042L3V
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for TADA2A
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TADA2A
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TADA2A Gene
Localization for TADA2A Gene
Subcellular locations from UniProtKB/Swiss-Prot for TADA2A Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
- Nuclear speckles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000125 | PCAF complex | IDA | 9674425 |
| GO:0005634 | nucleus | IEA,IBA | 21873635 |
| GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | IEA | -- |
| GO:0005694 | chromosome | IEA | -- |
| GO:0070461 | SAGA-type complex | IBA | 21873635 |
Pathways & Interactions for TADA2A Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Chromatin organization | ||
| 2 | RNA Polymerase II Transcription Initiation And Promoter Clearance |
Transcription Ligand-Dependent Transcription of Retinoid-Target genes
.32
|
|
Pathways by source for TADA2A Gene
3 Reactome pathways for TADA2A Gene
1 GeneGo (Thomson Reuters) pathway for TADA2A Gene
- Transcription Ligand-Dependent Transcription of Retinoid-Target genes
Interacting Proteins for TADA2A Gene
Selected Interacting proteins:
O75478-TAD2A_HUMAN
ENSP00000481091
for TADA2A Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for TADA2A
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000278 | mitotic cell cycle | IEA | -- |
| GO:0001932 | regulation of protein phosphorylation | IEA | -- |
| GO:0006338 | chromatin remodeling | IBA | 21873635 |
| GO:0006357 | regulation of transcription by RNA polymerase II | IEA,TAS | 8552087 |
| GO:0031063 | regulation of histone deacetylation | IEA | -- |
No data available for SIGNOR curated interactions for TADA2A Gene
Transcripts for TADA2A Gene
mRNA/cDNA for TADA2A Gene
- 4 REFSEQ mRNAs :
- 14 NCBI additional mRNA sequence :
- 16 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000610834 689 nts (view in UCSC)
- ENST00000612272 1948 nts (view in UCSC)
- ENST00000614112 561 nts (view in UCSC)
- ENST00000614122 1003 nts (view in UCSC)
- ENST00000615182 4236 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TADA2A - Starting at $85 >
- * TADA2A CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TADA2A
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TADA2A
-
Santa Cruz Biotechnology (SCBT) CRISPR for TADA2A
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TADA2A
- Browse OriGene Inhibitory RNA Products For TADA2A
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TADA2A
Clone products for research
- Applied Biological Materials (abm): Clones for TADA2A - Starting at $45 >
- * TADA2A as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
- MG207073
- MR207073
- MR207073L3
- MR207073L4
- RC200580
- RC200580L3
- RC200580L4
- RC204042
- RC204042L3
- RC204042L4
- RC228898
- RC228898L3
- RC228898L4
- RC237330
- RG200580
- RG204042
- RG228898
- RR201809
- RR201809L3
- RR201809L4
- MR207073L3V
- MR207073L4V
- RC200580L3V
- RC200580L4V
- RC204042L3V
- RC204042L4V
- RC228898L3V
- RC228898L4V
- RR201809L3V
- RR201809L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for TADA2A
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TADA2A
Relevant External Links for TADA2A Gene
- GeneLoc Exon Structure for
- TADA2A
Expression for TADA2A Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Ovary (Reproductive System)
- Secondary Oocyte Antral Follicle
-
Gonad
- Secondary Oocyte Antral Follicle
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TADA2A Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TADA2A
SOURCE GeneReport for Unigene cluster for TADA2A Gene:
Hs.500066mRNA Expression by UniProt/SwissProt for TADA2A Gene:
O75478-TAD2A_HUMAN
Tissue specificity:
Expressed in all tissues, but most abundantly in testis.
Evidence on tissue expression from TISSUES for TADA2A Gene
- Muscle(4.3)
- Spleen(4.2)
- Lymph node(4.2)
- Blood(4.1)
- Eye(4.1)
- Nervous system(2.1)
Primer products for research
-
OriGene qPCR primer pairs for TADA2A
-
OriGene qPCR primer pairs and template standards for TADA2A
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TADA2A Gene
Orthologs for TADA2A Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TADA2A 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | TADA2A 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | TADA2A 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Tada2a 30 17 |
|
||
| Rat (Rattus norvegicus) |
Mammalia | Tada2a 30 |
|
||
| Chicken (Gallus gallus) |
Aves | TADA2A 30 |
|
||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tada2a 30 |
|
||
| Str.10606 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | tada2a 30 |
|
||
| Dr.12657 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.1143 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Ada2a 30 |
|
||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ADA2 30 |
|
||
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0B01496g 30 |
|
||
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AER318C 30 |
|
||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | ADA2B 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os03g0750800 30 |
|
||
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU04459 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | ada2 30 |
|
- Species where no ortholog for TADA2A was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for TADA2A Gene
- ENSEMBL:
- Gene Tree for TADA2A (if available)
- TreeFam:
- Gene Tree for TADA2A (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TADA2A: view image
Paralogs for TADA2A Gene
Variants for TADA2A Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1462n106 | CNV | deletion | 24896259 |
| dgv3157n100 | CNV | gain | 25217958 |
| dgv524n67 | CNV | loss | 20364138 |
| dgv549e199 | CNV | deletion | 23128226 |
| dgv550e199 | CNV | deletion | 23128226 |
| esv1010097 | CNV | gain | 20482838 |
| esv2661747 | CNV | deletion | 23128226 |
| esv2715889 | CNV | deletion | 23290073 |
| esv2758687 | CNV | gain | 17122850 |
| esv2763164 | CNV | loss | 21179565 |
| esv3554385 | CNV | deletion | 23714750 |
| esv3640493 | CNV | gain | 21293372 |
| esv3640494 | CNV | gain | 21293372 |
| esv3640495 | OTHER | inversion | 21293372 |
| esv3640496 | CNV | loss | 21293372 |
| esv3640497 | CNV | loss | 21293372 |
| nsv1061860 | CNV | gain | 25217958 |
| nsv1136234 | CNV | deletion | 24896259 |
| nsv435684 | CNV | deletion | 17901297 |
| nsv476793 | CNV | novel sequence insertion | 20440878 |
| nsv9543 | CNV | loss | 18304495 |
Residual Variation Intolerance Score:
21.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.22;
40.01% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TADA2A Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TADA2A
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TADA2A Gene
Disorders for TADA2A Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chromosome 17q12 deletion syndrome |
|
|
Search TADA2A in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TADA2A
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for TADA2A Gene
Publications for TADA2A Gene
- Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor. (PMID: 9154805) Henriksson A … Wright AP (Molecular and cellular biology 1997) 3 4 23
- Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5. (PMID: 8552087) Candau R … Berger SL (Molecular and cellular biology 1996) 2 3 4
- CCDC134 interacts with hADA2a and functions as a regulator of hADA2a in acetyltransferase activity, DNA damage-induced apoptosis and cell cycle arrest. (PMID: 22644376) Huang J … Qiu X (Histochemistry and cell biology 2012) 3 4
- Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PMID: 20602615) Ruaño G … Wu AH (Pharmacogenomics 2010) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
ExternalLinks
Products for TADA2A Gene
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- Origene shrna, sirna, and RNAi products in human, mouse, rat for TADA2A
- Browse OriGene Inhibitory RNA Products For TADA2A
- OriGene qPCR primer pairs for TADA2A
- OriGene qPCR primer pairs and template standards for TADA2A
- OriGene CRISPR knockouts for TADA2A
- MG207073
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- MR207073L4
- RC200580
- RC200580L3
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- antibodies-online: Show 23 available TADA2A Antibodies ranked by validation data
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Sources for TADA2A Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB