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TAAR1 Gene(Protein Coding)

Trace Amine Associated Receptor 1

GCID:
GC06M132644
GIFtS:
46
Genes Participants
UDN Logo

Aliases for TAAR1 Gene

Aliases for TAAR1 Gene

  • Trace Amine Associated Receptor 1 2 3 5
  • Trace Amine Receptor 1 2 3 4
  • TRAR1 3 4
  • TAR1 3 4
  • TA1 3 4
  • Trace Amine-Associated Receptor 1 3
  • TaR-1 4

External Ids for TAAR1 Gene

Previous HGNC Symbols for TAAR1 Gene

  • TRAR1

Previous GeneCards Identifiers for TAAR1 Gene

  • GC06M133008
  • GC06M130541
  • GC06M132966

Summaries for TAAR1 Gene

Entrez Gene Summary for TAAR1 Gene

  • The protein encoded by this gene is a G-protein coupled receptor activated by trace amines. The encoded protein responds little or not at all to dopamine, serotonin, epinephrine, or histamine, but responds well to beta-phenylethylamine, p-tyramine, octopamine, and tryptamine. While primarily functioning in neurologic systems, there is evidence that this gene is involved in blood cell and immunologic functions as well. This gene is thought to be intronless. [provided by RefSeq, Nov 2015]

GeneCards Summary for TAAR1 Gene

TAAR1 (Trace Amine Associated Receptor 1) is a Protein Coding gene. Diseases associated with TAAR1 include Superficial Urinary Bladder Cancer and Paralytic Ileus. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and trace-amine receptor activity. An important paralog of this gene is TAAR2.

UniProtKB/Swiss-Prot for TAAR1 Gene

  • Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase.

Tocris Summary for TAAR1 Gene

  • The trace amine 1 (TA1) receptor (also known as the trace amine-associated receptor 1, TAAR1) is a class A GPCR that is activated by endogenous trace amines. To date, the TA1 receptor is the only trace amine-associated receptor that has been de-orphaned.

Gene Wiki entry for TAAR1 Gene

Additional gene information for TAAR1 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TAAR1 Gene

Genomics for TAAR1 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for TAAR1 Gene

Promoters and enhancers for TAAR1 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH06I132669 Enhancer 0.9 Ensembl ENCODE 0.3 -25.9 -25936 4.2 CTCF FOXA2 MAX RAD21 ZNF366 HNF4G ZNF143 SMC3 ZNF654 NFIA ENSG00000234484 VNN2 VNN3 SNORA33 SNORD101 SNORD100 RPS12 SLC18B1 VNN1 HLFP1
GH06I132624 Promoter 0.5 EPDnew 0.3 +21.6 21610 0.1 TAAR2 TAAR1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TAAR1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TAAR1 gene promoter:

Genomic Locations for TAAR1 Gene

Genomic Locations for TAAR1 Gene
chr6:132,644,984-132,646,003
(GRCh38/hg38)
Size:
1,020 bases
Orientation:
Minus strand
chr6:132,966,123-132,967,142
(GRCh37/hg19)

Genomic View for TAAR1 Gene

Genes around TAAR1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TAAR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TAAR1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TAAR1 Gene

Proteins for TAAR1 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for TAAR1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96RJ0-TAAR1_HUMAN
    Recommended name:
    Trace amine-associated receptor 1
    Protein Accession:
    Q96RJ0
    Secondary Accessions:
    • Q2M1W5
    • Q3MIH8
    • Q5VUQ1

    Protein attributes for TAAR1 Gene

    Size:
    339 amino acids
    Molecular mass:
    39092 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TAAR1 Gene

Protein Expression for TAAR1 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for TAAR1 Gene

  • Glycosylation at isoforms=10 and posLast=1717
  • Modification sites at PhosphoSitePlus

Other Protein References for TAAR1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TAAR1 Gene

Domains & Families for TAAR1 Gene

Gene Families for TAAR1 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • FDA approved drug targets
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for TAAR1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TAAR1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96RJ0

UniProtKB/Swiss-Prot:

TAAR1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with TAAR1: view

Function for TAAR1 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Molecular function for TAAR1 Gene

UniProtKB/Swiss-Prot Function:
Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase.

Phenotypes From GWAS Catalog for TAAR1 Gene

Gene Ontology (GO) - Molecular Function for TAAR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001594 trace-amine receptor activity IBA --
GO:0004871 signal transducer activity IEA --
GO:0004930 G-protein coupled receptor activity TAS 15718104
GO:0008227 G-protein coupled amine receptor activity IEA --
genes like me logo Genes that share ontologies with TAAR1: view
genes like me logo Genes that share phenotypes with TAAR1: view

Animal Models for TAAR1 Gene

MGI Knock Outs for TAAR1:

Animal Model Products

  • Taconic Biosciences Mouse Models for TAAR1

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TAAR1 Gene

Localization for TAAR1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TAAR1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TAAR1 gene
Compartment Confidence
plasma membrane 5
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for TAAR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IC,IEA --
genes like me logo Genes that share ontologies with TAAR1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TAAR1 Gene

Pathways & Interactions for TAAR1 Gene

genes like me logo Genes that share pathways with TAAR1: view

Interacting Proteins for TAAR1 Gene

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000275216%0d%0a9606.ENSP00000243673%0d%0a9606.ENSP00000358595%0d%0a9606.ENSP00000291294%0d%0a9606.ENSP00000379213%0d%0a9606.ENSP00000379514%0d%0a
Selected Interacting proteins: ENSP00000275216 Q96RJ0-TAAR1_HUMAN for TAAR1 Gene via STRING IID

Gene Ontology (GO) - Biological Process for TAAR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006171 cAMP biosynthetic process IDA 11723224
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with TAAR1: view

No data available for SIGNOR curated interactions for TAAR1 Gene

Drugs & Compounds for TAAR1 Gene

Products:

  1. Drug

(15) Drugs for TAAR1 Gene - From: DrugBank, DGIdb, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Amphetamine Approved, Illicit, Investigational Pharma Target, agonist, antagonist 131
Methamphetamine Approved, Illicit Pharma Target, agonist, antagonist 267
Dextroamphetamine Approved, Illicit Pharma Full agonist, Agonist, Target, agonist 76
Propylhexedrine Approved Pharma Target, agonist 0
Epinephrine Approved, Vet_approved Pharma 1095

(3) Additional Compounds for TAAR1 Gene - From: Novoseek, IUPHAR, and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
beta-phenylethylamine
Full agonist, Agonist
Ractopamine hydrochloride
90274-24-1

(2) Tocris Compounds for TAAR1 Gene

Compound Action Cas Number
EPPTB Trace amine 1 (TA1) receptor antagonist/inverse agonist 1110781-88-8
Ractopamine hydrochloride Trace amine 1 (TA1) receptor agonist 90274-24-1
genes like me logo Genes that share compounds with TAAR1: view

Transcripts for TAAR1 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for TAAR1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TAAR1 Gene

Trace amine associated receptor 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TAAR1 Gene

No ASD Table

Relevant External Links for TAAR1 Gene

GeneLoc Exon Structure for
TAAR1
ECgene alternative splicing isoforms for
TAAR1

Expression for TAAR1 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TAAR1 Gene

mRNA expression in normal human tissues for TAAR1 Gene
mRNA expression by BioGPS for TAAR1 GenemRNA expression by GTEx for TAAR1 Gene

Protein differential expression in normal tissues from HIPED for TAAR1 Gene

This gene is overexpressed in Salivary gland (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TAAR1 Gene



Protein tissue co-expression partners for TAAR1 Gene

NURSA nuclear receptor signaling pathways regulating expression of TAAR1 Gene:

TAAR1

SOURCE GeneReport for Unigene cluster for TAAR1 Gene:

Hs.375030

mRNA Expression by UniProt/SwissProt for TAAR1 Gene:

Q96RJ0-TAAR1_HUMAN
Tissue specificity: Detected in low levels in discrete regions within the central nervous system and in several peripheral tissues. Moderately expressed in stomach. Low levels in amygdala, kidney, and lung, and small intestine. Trace amounts in cerebellum, dorsal root ganglia, hippocampus, hypothalamus, liver, medulla, pancreas, pituitary, pontine reticular formation, prostate, skeletal muscle and spleen.

Evidence on tissue expression from TISSUES for TAAR1 Gene

  • Lung(4.1)
  • Thyroid gland(2.3)
  • Nervous system(2.1)
genes like me logo Genes that share expression patterns with TAAR1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TAAR1 Gene

Orthologs for TAAR1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TAAR1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia TAAR1 33 34
  • 99.21 (n)
cow
(Bos Taurus)
 Mammalia TAAR1 34
  • 84 (a)
 OneToOne
rat
(Rattus norvegicus)
 Mammalia Taar1 33
  • 79.12 (n)
mouse
(Mus musculus)
 Mammalia Taar1 33 16 34
  • 78.92 (n)
oppossum
(Monodelphis domestica)
 Mammalia TAAR1 34
  • 76 (a)
 OneToOne
platypus
(Ornithorhynchus anatinus)
 Mammalia TAAR1 34
  • 68 (a)
 OneToOne
chicken
(Gallus gallus)
 Aves TAAR1 33 34
  • 70.18 (n)
lizard
(Anolis carolinensis)
 Reptilia TAAR1 34
  • 64 (a)
 OneToOne
tropical clawed frog
(Silurana tropicalis)
 Amphibia taar1 33
  • 67.97 (n)
zebrafish
(Danio rerio)
 Actinopterygii taar1b 33 34
  • 56.9 (n)
taar10b 34
  • 49 (a)
 OneToMany
taar10d 34
  • 48 (a)
 OneToMany
taar10a 34
  • 47 (a)
 OneToMany
taar10c 34
  • 47 (a)
 OneToMany
TAAR1 (22 of 92) 34
  • 46 (a)
 OneToMany
taar10 34
  • 46 (a)
 OneToMany
taar11 34
  • 45 (a)
 OneToMany
TAAR1 (33 of 92) 34
  • 44 (a)
 OneToMany
taar16b 34
  • 37 (a)
 OneToMany
taar19i 34
  • 36 (a)
 OneToMany
taar20t 34
  • 36 (a)
 OneToMany
taar20x 34
  • 36 (a)
 OneToMany
TAAR1 (17 of 92) 34
  • 35 (a)
 OneToMany
TAAR1 (44 of 92) 34
  • 35 (a)
 OneToMany
TAAR1 (62 of 92) 34
  • 35 (a)
 OneToMany
TAAR1 (64 of 92) 34
  • 35 (a)
 OneToMany
TAAR1 (73 of 92) 34
  • 35 (a)
 OneToMany
taar19c 34
  • 35 (a)
 OneToMany
taar19e 34
  • 35 (a)
 OneToMany
taar19g 34
  • 35 (a)
 OneToMany
taar19h 34
  • 35 (a)
 OneToMany
taar19n 34
  • 35 (a)
 OneToMany
taar19o 34
  • 35 (a)
 OneToMany
taar19p 34
  • 35 (a)
 OneToMany
taar19s 34
  • 35 (a)
 OneToMany
taar19t 34
  • 35 (a)
 OneToMany
taar20b 34
  • 35 (a)
 OneToMany
taar20d1 34
  • 35 (a)
 OneToMany
taar20l 34
  • 35 (a)
 OneToMany
taar20w 34
  • 35 (a)
 OneToMany
taar32 34
  • 35 (a)
 OneToMany
TAAR1 (19 of 92) 34
  • 34 (a)
 OneToMany
TAAR1 (21 of 92) 34
  • 34 (a)
 OneToMany
TAAR1 (75 of 92) 34
  • 34 (a)
 OneToMany
taar14i 34
  • 34 (a)
 OneToMany
taar14l 34
  • 34 (a)
 OneToMany
taar15 34
  • 34 (a)
 OneToMany
taar16a 34
  • 34 (a)
 OneToMany
taar18a 34
  • 34 (a)
 OneToMany
taar18b 34
  • 34 (a)
 OneToMany
taar18h 34
  • 34 (a)
 OneToMany
taar19a 34
  • 34 (a)
 OneToMany
taar19d 34
  • 34 (a)
 OneToMany
taar19f 34
  • 34 (a)
 OneToMany
taar19k 34
  • 34 (a)
 OneToMany
taar19m 34
  • 34 (a)
 OneToMany
taar19q 34
  • 34 (a)
 OneToMany
taar20a 34
  • 34 (a)
 OneToMany
taar20a1 34
  • 34 (a)
 OneToMany
taar20b1 34
  • 34 (a)
 OneToMany
taar20c1 34
  • 34 (a)
 OneToMany
taar20g 34
  • 34 (a)
 OneToMany
taar20j 34
  • 34 (a)
 OneToMany
taar20n 34
  • 34 (a)
 OneToMany
taar20o 34
  • 34 (a)
 OneToMany
taar20p 34
  • 34 (a)
 OneToMany
taar20q 34
  • 34 (a)
 OneToMany
taar20z 34
  • 34 (a)
 OneToMany
TAAR1 (32 of 92) 34
  • 33 (a)
 OneToMany
TAAR1 (42 of 92) 34
  • 33 (a)
 OneToMany
TAAR1 (55 of 92) 34
  • 33 (a)
 OneToMany
TAAR1 (74 of 92) 34
  • 33 (a)
 OneToMany
taar14a 34
  • 33 (a)
 OneToMany
taar14d 34
  • 33 (a)
 OneToMany
taar14e 34
  • 33 (a)
 OneToMany
taar14f 34
  • 33 (a)
 OneToMany
taar14h 34
  • 33 (a)
 OneToMany
taar18e 34
  • 33 (a)
 OneToMany
taar18g 34
  • 33 (a)
 OneToMany
taar18i 34
  • 33 (a)
 OneToMany
taar18j 34
  • 33 (a)
 OneToMany
taar19b 34
  • 33 (a)
 OneToMany
taar19j 34
  • 33 (a)
 OneToMany
taar19u 34
  • 33 (a)
 OneToMany
taar20c 34
  • 33 (a)
 OneToMany
taar20f 34
  • 33 (a)
 OneToMany
taar20r 34
  • 33 (a)
 OneToMany
taar20u 34
  • 33 (a)
 OneToMany
TAAR1 (7 of 92) 34
  • 32 (a)
 OneToMany
taar14g 34
  • 32 (a)
 OneToMany
taar16f 34
  • 32 (a)
 OneToMany
taar16g 34
  • 32 (a)
 OneToMany
taar17a 34
  • 32 (a)
 OneToMany
taar18d 34
  • 32 (a)
 OneToMany
taar18f 34
  • 32 (a)
 OneToMany
taar19l 34
  • 32 (a)
 OneToMany
taar20h 34
  • 32 (a)
 OneToMany
taar20i 34
  • 32 (a)
 OneToMany
taar20m 34
  • 32 (a)
 OneToMany
taar14j 34
  • 30 (a)
 OneToMany
taar18c 34
  • 23 (a)
 OneToMany
Species where no ortholog for TAAR1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TAAR1 Gene

ENSEMBL:
Gene Tree for TAAR1 (if available)
TreeFam:
Gene Tree for TAAR1 (if available)

Paralogs for TAAR1 Gene

Paralogs for TAAR1 Gene

(16) SIMAP similar genes for TAAR1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for TAAR1 Gene

genes like me logo Genes that share paralogs with TAAR1: view

Variants for TAAR1 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for TAAR1 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000951954 -- 132,646,433(-) G/A upstream_transcript_variant
rs1001903959 -- 132,647,058(-) G/A upstream_transcript_variant
rs1002366315 -- 132,647,231(-) T/C upstream_transcript_variant
rs1002456797 -- 132,646,131(-) T/A upstream_transcript_variant
rs1002896730 -- 132,646,297(-) C/T upstream_transcript_variant

Variation tolerance for TAAR1 Gene

Residual Variation Intolerance Score: 86.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.31; 41.31% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TAAR1 Gene

Human Gene Mutation Database (HGMD)
TAAR1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TAAR1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TAAR1 Gene

Disorders for TAAR1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for TAAR1 Gene - From: HGMD and DISEASES

Disorder Aliases PubMed IDs
superficial urinary bladder cancer
  • superficial urinary bladder carcinoma
paralytic ileus
- elite association - COSMIC cancer census association via MalaCards
Search TAAR1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for TAAR1

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with TAAR1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TAAR1 Gene

Publications for TAAR1 Gene

  1. Trace amines: identification of a family of mammalian G protein-coupled receptors. (PMID: 11459929) Borowsky B … Gerald C (Proceedings of the National Academy of Sciences of the United States of America 2001) 2 3 4 25 58
  2. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. (PMID: 15718104) Lindemann L … Hoener MC (Genomics 2005) 2 3 4 58
  3. Structure-activity correlations for beta-phenethylamines at human trace amine receptor 1. (PMID: 18602830) Lewin AH … Mascarella SW (Bioorganic & medicinal chemistry 2008) 3 22 58
  4. Expression of neuronal trace amine-associated receptor (Taar) mRNAs in leukocytes. (PMID: 17900709) Nelson DA … Bost KL (Journal of neuroimmunology 2007) 3 22 58
  5. Trace amine-associated receptor 1 displays species-dependent stereoselectivity for isomers of methamphetamine, amphetamine, and para-hydroxyamphetamine. (PMID: 17218486) Reese EA … Grandy DK (The Journal of pharmacology and experimental therapeutics 2007) 22 25 58

Products for TAAR1 Gene

Sources for TAAR1 Gene

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