Aliases for SYTL5 Gene
External Ids for SYTL5 Gene
Previous GeneCards Identifiers for SYTL5 Gene
The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
GeneCards Summary for SYTL5 Gene
SYTL5 (Synaptotagmin Like 5) is a Protein Coding gene. Among its related pathways are wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF) and Deregulation of Rab and Rab Effector Genes in Bladder Cancer. Gene Ontology (GO) annotations related to this gene include calcium ion binding and syntaxin binding. An important paralog of this gene is SYTL4.
UniProtKB/Swiss-Prot for SYTL5 Gene
May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids.