Aliases for SYT10 Gene
External Ids for SYT10 Gene
Previous GeneCards Identifiers for SYT10 Gene
GeneCards Summary for SYT10 Gene
SYT10 (Synaptotagmin 10) is a Protein Coding gene. Diseases associated with SYT10 include Kaufman Oculocerebrofacial Syndrome and Kagami-Ogata Syndrome. Among its related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. Gene Ontology (GO) annotations related to this gene include calcium ion binding and identical protein binding. An important paralog of this gene is SYT6.
UniProtKB/Swiss-Prot Summary for SYT10 Gene
Ca(2+) sensor specifically required for the Ca(2+)-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. Not involved in Ca(2+)-dependent synaptic vesicle exocytosis (By similarity). Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity).