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SYPL2 (Synaptophysin Like 2) is a Protein Coding gene. Diseases associated with SYPL2 include Hypophosphatemic Nephrolithiasis/Osteoporosis and T Cell And Nk Cell Immunodeficiency. Gene Ontology (GO) annotations related to this gene include transporter activity. An important paralog of this gene is SYNPR.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0017075 | syntaxin-1 binding | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008021 | synaptic vesicle | IEA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO:0030672 | synaptic vesicle membrane | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006874 | cellular calcium ion homeostasis | IEA | -- |
GO:0007507 | heart development | IEA | -- |
GO:0021762 | substantia nigra development | HEP | 22926577 |
GO:0033292 | T-tubule organization | IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | SYPL2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | SYPL2 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Sypl2 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Sypl2 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | SYPL2 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | SYPL2 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | SYPL2 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | SYPL2 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | SYPL2 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | sypl2 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | sypl2b 31 |
|
OneToMany | |
sypl2a 31 |
|
OneToMany | |||
Worm (Caenorhabditis elegans) |
Secernentea | sph-1 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3578079 | CNV | loss | 25503493 |
Disorder | Aliases | PubMed IDs |
---|---|---|
hypophosphatemic nephrolithiasis/osteoporosis |
|
|
t cell and nk cell immunodeficiency |
|
|
immunodeficiency 10 |
|
|
stormorken syndrome |
|
|
malignant hyperthermia |
|
|