External Ids for SYNGR3 Gene
Previous GeneCards Identifiers for SYNGR3 Gene
This gene encodes an integral membrane protein. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it is a synaptic vesicle protein that also interacts with the dopamine transporter. The gene product belongs to the synaptogyrin gene family. [provided by RefSeq, Dec 2010]
GeneCards Summary for SYNGR3 Gene
SYNGR3 (Synaptogyrin 3) is a Protein Coding gene. Diseases associated with SYNGR3 include Deafness, Autosomal Recessive 74 and Deafness, Autosomal Recessive 86. Gene Ontology (GO) annotations related to this gene include protein N-terminus binding and SH2 domain binding. An important paralog of this gene is SYNGR1.
UniProtKB/Swiss-Prot Summary for SYNGR3 Gene
May play a role in regulated exocytosis. May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from the synaptic cleft into the presynaptic terminal.