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This gene encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells. The gene belongs to the synaptogyrin gene family. Alternat... See more...
Aliases for SYNGR2 Gene
External Ids for SYNGR2 Gene
- HGNC: 11499
- NCBI Entrez Gene: 9144
- Ensembl: ENSG00000108639
- OMIM®: 603926
- UniProtKB/Swiss-Prot: O43760
Previous GeneCards Identifiers for SYNGR2 Gene
- GC17P075988
- GC17P079151
- GC17P076625
- GC17P076761
- GC17P073676
- GC17P076164
- GC17P071589
Summaries for SYNGR2 Gene
-
This gene encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells. The gene belongs to the synaptogyrin gene family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneCards Summary for SYNGR2 Gene
SYNGR2 (Synaptogyrin 2) is a Protein Coding gene. Diseases associated with SYNGR2 include Charcot-Marie-Tooth Disease, Type 4D and Leukoencephalopathy With Vanishing White Matter. An important paralog of this gene is SYNGR1.
UniProtKB/Swiss-Prot Summary for SYNGR2 Gene
-
May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane.
-
(Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication.
Additional gene information for SYNGR2 Gene
- HGNC (11499)
- NCBI Entrez Gene (9144)
- Ensembl (ENSG00000108639)
- OMIM® (603926)
- UniProtKB/Swiss-Prot (O43760)
- Open Targets Platform(ENSG00000108639)
- Monarch Initiative
- Search for SYNGR2 at DataMed
- Search for SYNGR2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SYNGR2 Gene
Genomics for SYNGR2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SYNGR2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SYNGR2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SYNGR2
- Top Transcription factor binding sites by QIAGEN in the SYNGR2 gene promoter:
-
- AML1a
- GATA-1
- Nkx6-1
- p53
- Pax-2
- Pax-2a
- Pax-2b
- Pax-5
Genomic Locations for SYNGR2 Gene
Latest Assembly
- chr17:78,168,545-78,173,527
- (GRCh38/hg38)
- Size:
- 4,983 bases
- Orientation:
- Plus strand
Previous Assembly
- chr17:76,164,626-76,169,045
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 4,420 bases
- Orientation:
- Plus strand
- chr17:76,164,639-76,169,608
- (GRCh37/hg19 by Ensembl)
- Size:
- 4,970 bases
- Orientation:
- Plus strand
Genomic View for SYNGR2 Gene
Genes around SYNGR2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.3 by HGNC
- 17q25.3 by Entrez Gene
- 17q25.3 by Ensembl
SYNGR2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SYNGR2 Gene
Proteins for SYNGR2 Gene
-
Protein details for SYNGR2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O43760-SNG2_HUMAN
- Recommended name:
- Synaptogyrin-2
- Protein Accession:
- O43760
- O43762
- Q3KQZ2
- Q658S7
Protein attributes for SYNGR2 Gene
- Size:
- 224 amino acids
- Molecular mass:
- 24810 Da
- Quaternary structure:
-
- (Microbial infection) Interacts with SFTS phlebovirus protein NSs; may be involved in virus replication.
Protein Expression for SYNGR2 Gene
Post-translational modifications for SYNGR2 Gene
- May be tyrosine phosphorylated by Src.
-
Ubiquitination at Lys10
- NX_O43760 (NX_O43760-1)
- Modification sites at PhosphoSitePlus
Other Protein References for SYNGR2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences SYNGR2 / Synaptogyrin 2 Antibody (LS-B5070) and SYNGR2 / Synaptogyrin 2 Antibody (LS-A9135)
-
Custom Antibody ServicesOriGene Antibodies for SYNGR2
- Novus Biologicals Antibodies for SYNGR2
-
Abcam antibodies for SYNGR2
- Invitrogen Antibodies for SYNGR2 (AFLGC-SYNGR2)
-
Boster Bio Antibodies for SYNGR2
-
Custom Antibody ServicesProSci Antibodies for SYNGR2
-
Santa Cruz Biotechnology (SCBT) Antibodies for SYNGR2
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for SYNGR2
- Origene Custom Protein Services for SYNGR2
- antibodies-online: Show 5 available SYNGR2 Proteins ranked by validation data
- Compare Top SYNGR2 Proteins
-
Quality Products:
-
Abcam proteins for SYNGR2
Assay products for research
No data available for DME Specific Peptides for SYNGR2 Gene
Domains & Families for SYNGR2 Gene
Gene Families for SYNGR2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for SYNGR2 Gene
- InterPro:
- Blocks:
-
- Marvel
- ProtoNet:
Suggested Antigen Peptide Sequences for SYNGR2 Gene
- GenScript: Design optimal peptide antigens:
-
- SYNGR2 protein (Q3KQZ2_HUMAN)
- Cellugyrin (SNG2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O43760- Family:
-
- Belongs to the synaptogyrin family.
Function for SYNGR2 Gene
Molecular function for SYNGR2 Gene
- UniProtKB/Swiss-Prot Function:
- May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane.
- UniProtKB/Swiss-Prot Function:
- (Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication.
- UniProtKB/Swiss-Prot Induction:
- (Microbial infection) Up-regulated upon SFTS phlebovirus infection (at protein level).
- GENATLAS Biochemistry:
- synaptogyrin 2,putative vesicle protein,expressed in all tissues except in brain
Phenotypes From GWAS Catalog for SYNGR2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for SYNGR2 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SYNGR2 - Starting at $85 >
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- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
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-
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miRNA for SYNGR2 Gene
- miRTarBase miRNAs that target SYNGR2
-
- hsa-miR-124-3p (MIRT002717)
- hsa-miR-9-5p (MIRT021478)
- hsa-miR-98-5p (MIRT027625)
- hsa-miR-96-5p (MIRT027906)
- hsa-let-7b-5p (MIRT032328)
- hsa-miR-455-3p (MIRT037835)
- hsa-miR-484 (MIRT042262)
- hsa-miR-324-5p (MIRT043163)
- hsa-miR-320a (MIRT044770)
- hsa-miR-374a-5p (MIRT147633)
- hsa-miR-3919 (MIRT289396)
- hsa-miR-3925-5p (MIRT289397)
- hsa-miR-185-3p (MIRT466742)
- hsa-miR-762 (MIRT466743)
- hsa-miR-5001-5p (MIRT466744)
- hsa-miR-4498 (MIRT466745)
- hsa-miR-4492 (MIRT466746)
- hsa-miR-548au-3p (MIRT466747)
- hsa-miR-449b-5p (MIRT466748)
- hsa-miR-449a (MIRT466749)
- hsa-miR-34c-5p (MIRT466750)
- hsa-miR-34a-5p (MIRT466751)
- hsa-miR-423-5p (MIRT466752)
- hsa-miR-3184-5p (MIRT466753)
- hsa-miR-6868-5p (MIRT466754)
- hsa-miR-584-3p (MIRT466755)
- hsa-miR-125a-3p (MIRT466756)
- hsa-miR-6813-5p (MIRT466757)
- hsa-miR-6085 (MIRT466758)
- hsa-miR-6856-5p (MIRT466759)
- hsa-miR-6758-5p (MIRT466760)
- hsa-miR-552-3p (MIRT466761)
- hsa-miR-4311 (MIRT466762)
- hsa-miR-665 (MIRT466763)
- hsa-miR-7150 (MIRT571606)
- hsa-miR-182-5p (MIRT571607)
- hsa-miR-1271-5p (MIRT571608)
- hsa-miR-361-3p (MIRT720404)
- hsa-miR-1827 (MIRT763127)
- hsa-miR-199a-3p (MIRT763626)
- hsa-miR-199b-3p (MIRT763637)
- hsa-miR-222-5p (MIRT763950)
- hsa-miR-223-3p (MIRT763954)
- hsa-miR-3129-5p (MIRT764871)
- hsa-miR-4271 (MIRT768259)
- hsa-miR-4649-3p (MIRT770678)
- hsa-miR-4697-3p (MIRT771270)
- hsa-miR-4717-3p (MIRT771424)
- hsa-miR-4725-3p (MIRT771629)
- hsa-miR-5589-3p (MIRT774805)
- hsa-miR-585-5p (MIRT775340)
- hsa-miR-6500-3p (MIRT776475)
- hsa-miR-6780b-5p (MIRT779050)
- hsa-miR-7160-5p (MIRT781645)
- hsa-miR-936 (MIRT782771)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SYNGR2
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Clone products for research
- Applied Biological Materials (abm): Clones for SYNGR2 - Starting at $45 >
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- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SYNGR2
Cell Lines for research
-
Horizon Cell Lines for SYNGR2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SYNGR2 Gene
Localization for SYNGR2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SYNGR2 Gene
- Cytoplasmic vesicle membrane. Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Multi-pass membrane protein. Note=Localizes to cytoplasmic vesicles associated with the recycling endosomes. {ECO:0000250 UniProtKB:O54980}.
- Lipid droplet. Note=(Microbial infection) Upon SFTS phlebovirus infection, the protein localizes in lipid droplets and inclusion bodies. {ECO:0000269 PubMed:27226560}.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| plasma membrane | 3 |
| golgi apparatus | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
| lysosome | 1 |
- Golgi apparatus (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005811 | lipid droplet | IEA | -- |
| GO:0008021 | synaptic vesicle | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA,NAS | 9760194 |
| GO:0030054 | cell junction | IEA | -- |
Pathways & Interactions for SYNGR2 Gene
Interacting Proteins for SYNGR2 Gene
Selected Interacting proteins:
O43760-SNG2_HUMAN
ENSP00000225777
for SYNGR2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for SYNGR2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016032 | viral process | IEA | -- |
| GO:0045055 | regulated exocytosis | ISS | -- |
| GO:0048499 | synaptic vesicle membrane organization | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for SYNGR2 Gene
Transcripts for SYNGR2 Gene
mRNA/cDNA for SYNGR2 Gene
- 3 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000225777 1495 nts (view in UCSC)
- ENST00000585591 949 nts (view in UCSC)
- ENST00000588282 1553 nts (view in UCSC)
- ENST00000589168 2125 nts (view in UCSC)
- ENST00000589183 796 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SYNGR2 - Starting at $85 >
- * SYNGR2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for SYNGR2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SYNGR2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SYNGR2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SYNGR2
- Browse OriGene Inhibitory RNA Products For SYNGR2
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Clone products for research
- Applied Biological Materials (abm): Clones for SYNGR2 - Starting at $45 >
- * SYNGR2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for SYNGR2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SYNGR2
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||
| SP2: | - |
Relevant External Links for SYNGR2 Gene
- GeneLoc Exon Structure for
- SYNGR2
Expression for SYNGR2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Glial Cells
- Myelinating Oligodendrocyte Cells Forebrain White Matter
- Intestine (Gastrointestinal Tract)
- Bone (Muscoskeletal System)
-
Colon (Gastrointestinal Tract)
-
Prostate (Endocrine System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Esophagus (Gastrointestinal Tract)
-
Stomach (Gastrointestinal Tract)
-
Pancreas (Endocrine System)
This gene is overexpressed in Nasal epithelium (30.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SYNGR2 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SYNGR2
SOURCE GeneReport for Unigene cluster for SYNGR2 Gene:
Hs.464210mRNA Expression by UniProt/SwissProt for SYNGR2 Gene:
O43760-SNG2_HUMAN
Tissue specificity:
Ubiquitous; low expression in brain.
Evidence on tissue expression from TISSUES for SYNGR2 Gene
- Lung(4.8)
- Skin(4.7)
- Stomach(4.4)
- Nervous system(3.9)
- Pancreas(3.5)
- Intestine(3.4)
- Muscle(3.3)
- Heart(2.5)
- Kidney(2.4)
- Liver(2.2)
- Spleen(2)
Primer products for research
-
OriGene qPCR primer pairs for SYNGR2
-
OriGene qPCR primer pairs and template standards for SYNGR2
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SYNGR2 Gene
Orthologs for SYNGR2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SYNGR2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SYNGR2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SYNGR2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Syngr2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Syngr2 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SYNGR2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | SYNGR2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SYNGR2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | syngr2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | LOC100537807 30 |
|
||
| syngr2b 31 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | synaptogyrin 31 32 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | sng-1 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for SYNGR2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for SYNGR2 Gene
- ENSEMBL:
- Gene Tree for SYNGR2 (if available)
- TreeFam:
- Gene Tree for SYNGR2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SYNGR2: view image
Paralogs for SYNGR2 Gene
(3) SIMAP similar genes for SYNGR2 Gene using alignment to 6 proteins:
- SNG2_HUMAN
- K7EJ35_HUMAN
- K7ELD9_HUMAN
- K7ELS8_HUMAN
- K7ENG9_HUMAN
- Q3KQZ2_HUMAN
Pseudogenes.org Pseudogenes for SYNGR2 Gene
Variants for SYNGR2 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
67.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.58;
65.20% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SYNGR2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SYNGR2
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SYNGR2 Gene
Disorders for SYNGR2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| charcot-marie-tooth disease, type 4d |
|
|
| leukoencephalopathy with vanishing white matter |
|
|
| primary autosomal recessive microcephaly |
|
|
Search SYNGR2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SYNGR2
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for SYNGR2 Gene
Publications for SYNGR2 Gene
- Characterization of the human synaptogyrin gene family. (PMID: 9760194) Kedra D … Dumanski JP (Human genetics 1998) 2 3 4 23
- Synaptogyrin-2 Promotes Replication of a Novel Tick-borne Bunyavirus through Interacting with Viral Nonstructural Protein NSs. (PMID: 27226560) Sun Q … Xing Z (The Journal of biological chemistry 2016) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 4
- A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export. (PMID: 33144569) van den Boomen DJH … Lehner PJ (Nature communications 2020) 3
ExternalLinks
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- VectorBuilder Stable cell line generation for SYNGR2
- antibodies-online: Show 18 available SYNGR2 Antibodies ranked by validation data
- Compare Top SYNGR2 Antibodies
- antibodies-online: Search results for available SYNGR2 related products ranked by validation data
- antibodies-online: Show 5 available SYNGR2 Proteins ranked by validation data
- Compare Top SYNGR2 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for SYNGR2
- Search Santa Cruz Biotechnology (SCBT) for SYNGR2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SYNGR2
- Custom Antibody ServicesProSci Antibodies for SYNGR2
- Search for SYNGR2 Proteins at ProSci
- Horizon Cell Lines for SYNGR2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SYNGR2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SYNGR2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SYNGR2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SYNGR2
- Boster Bio Antibodies for SYNGR2
- Browse Boster Bio ELISA Kits
Sources for SYNGR2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB