External Ids for SYNGR1 Gene
Previous GeneCards Identifiers for SYNGR1 Gene
This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for SYNGR1 Gene
SYNGR1 (Synaptogyrin 1) is a Protein Coding gene. Diseases associated with SYNGR1 include Megalencephalic Leukoencephalopathy With Subcortical Cysts 1 and Berylliosis. Among its related pathways are Innate Immune System. An important paralog of this gene is SYNGR3.
UniProtKB/Swiss-Prot Summary for SYNGR1 Gene
May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).