SYN3 Gene (Protein Coding)

Synapsin III

GC22M032512
GIFtS:
42
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The ... See more...

Aliases for SYN3 Gene

Aliases for SYN3 Gene

  • Synapsin III 2 3 4 5
  • Synapsin-3 2 3 4
  • CN28H9.2 (Synapsin III) 3
  • SYN3 5

External Ids for SYN3 Gene

Previous GeneCards Identifiers for SYN3 Gene

  • GC22M029604
  • GC22M031233
  • GC22M032908
  • GC22M015865

Summaries for SYN3 Gene

Entrez Gene Summary for SYN3 Gene

  • This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq, Oct 2008]

GeneCards Summary for SYN3 Gene

SYN3 (Synapsin III) is a Protein Coding gene. Diseases associated with SYN3 include Aland Island Eye Disease and Seizure Disorder. Among its related pathways are Synaptic vesicle cycle and Neurotransmitter Release Cycle. An important paralog of this gene is SYN2.

UniProtKB/Swiss-Prot Summary for SYN3 Gene

  • May be involved in the regulation of neurotransmitter release and synaptogenesis.

Gene Wiki entry for SYN3 Gene

Additional gene information for SYN3 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SYN3 Gene

Genomics for SYN3 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for SYN3 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH22J033057 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas 250.7 +0.1 68 1 MXD4 CTCF ZIC2 SIN3A SMAD4 SAP130 GABPB1 DMAP1 TBP CREM SYN3 ENSG00000228194 TIMP3
GH22J032799 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 5.4 +255.7 255743 6 ZIC2 SIN3A VEZF1 ZNF341 KLF9 SP2 TBP DRAP1 JUND ZBTB48 TIMP3 SYN3 lnc-LARGE1-3 lnc-BPIFC-4 lnc-TIMP3-2
GH22J032818 Enhancer 0.8 Ensembl ENCODE dbSUPER 14.3 +239.4 239366 4 ZSCAN4 EGR2 ZNF239 POLR2A ZFHX2 SYN3 ENSG00000229673 TIMP3 lnc-LARGE1-3 piR-43105-432 lnc-BPIFC-4 lnc-TIMP3-2
GH22J032794 Enhancer 1.3 Ensembl ENCODE CraniofacialAtlas dbSUPER 6.4 +262.5 262480 3.4 CTCF KDM6A REST FOXA2 SMAD4 SAP130 ETV4 SMC3 RAD21 RARA SYN3 TIMP3 ENSG00000229673 lnc-BPIFC-4 lnc-TIMP3-2 FBXO7
GH22J033034 Enhancer 0.6 Ensembl 11.8 +22.7 22680 1.8 RXRA FOXA2 ZBTB33 JUND HNF4A FOXA1 MAX SP1 EGR1 NR2F2 SYN3 ENSG00000228194 TIMP3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SYN3 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SYN3

Top Transcription factor binding sites by QIAGEN in the SYN3 gene promoter:
  • AP-2gamma
  • ATF-2
  • Bach2
  • E47
  • E4BP4
  • HNF-3beta
  • Pax-4a
  • STAT5A
  • Tal-1
  • TGIF

Genomic Locations for SYN3 Gene

Latest Assembly
chr22:32,507,820-33,058,381
(GRCh38/hg38)
Size:
550,562 bases
Orientation:
Minus strand

Previous Assembly
chr22:32,903,807-33,454,367
(GRCh37/hg19 by Entrez Gene)
Size:
550,561 bases
Orientation:
Minus strand

chr22:32,908,539-33,454,358
(GRCh37/hg19 by Ensembl)
Size:
545,820 bases
Orientation:
Minus strand

Genomic View for SYN3 Gene

Genes around SYN3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SYN3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SYN3 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SYN3 Gene

Proteins for SYN3 Gene

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  • Protein details for SYN3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O14994-SYN3_HUMAN
    Recommended name:
    Synapsin-3
    Protein Accession:
    O14994
    Secondary Accessions:
    • B1B1F9

    Protein attributes for SYN3 Gene

    Size:
    580 amino acids
    Molecular mass:
    63303 Da
    Quaternary structure:
    • Interacts with CAPON.
    Miscellaneous:
    • Regulated by calcium. Calcium inhibits ATP binding to the C-domain.

    Three dimensional structures from OCA and Proteopedia for SYN3 Gene

neXtProt entry for SYN3 Gene

Protein Expression for SYN3 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for SYN3 Gene

  • Phosphorylation at Ser-9 dissociates synapsins from synaptic vesicles.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SYN3 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibodies for research

  • Boster Bio Antibodies for SYN3

No data available for DME Specific Peptides for SYN3 Gene

Domains & Families for SYN3 Gene

Gene Families for SYN3 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for SYN3 Gene

InterPro:
Blocks:
  • Synapsin
ProtoNet:

Suggested Antigen Peptide Sequences for SYN3 Gene

GenScript: Design optimal peptide antigens:
  • Synapsin III, isoform CRA_f (B1B1F9_HUMAN)
  • cDNA FLJ57587, highly similar to Synapsin-3 (B4DTE0_HUMAN)
  • Synapsin III (Q17R54_HUMAN)
  • Synapsin III (SYN3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

O14994

UniProtKB/Swiss-Prot:

SYN3_HUMAN :
  • The A region binds phospholipids with a preference for negatively charged species.
  • Belongs to the synapsin family.
Domain:
  • The A region binds phospholipids with a preference for negatively charged species.
Family:
  • Belongs to the synapsin family.
genes like me logo Genes that share domains with SYN3: view

Function for SYN3 Gene

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  6. Cell Lines for research

Molecular function for SYN3 Gene

UniProtKB/Swiss-Prot Function:
May be involved in the regulation of neurotransmitter release and synaptogenesis.
GENATLAS Biochemistry:
synapsin IIIa,synaptic vesicle-associated phosphoprotein,involved in the regulation of neurotransmitter release,synaptogenesis and synaptic plasticity,with six transcripts (SYN3A to SYN3F),SYN3A,3B,3C deleted in fetal and adult brain,SYN30 only in fetal CNS,SYN3E and 3F non neuronal

Phenotypes From GWAS Catalog for SYN3 Gene

Gene Ontology (GO) - Molecular Function for SYN3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0005524 ATP binding TAS 15217342
genes like me logo Genes that share ontologies with SYN3: view
genes like me logo Genes that share phenotypes with SYN3: view

Animal Models for SYN3 Gene

MGI Knock Outs for SYN3:
  • Syn3 Syn3<tm1Pggd>
  • Syn3 Syn3<tm1.1(KOMP)Vlcg>

Animal Models for research

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SYN3

Clone products for research

  • Addgene plasmids for SYN3

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SYN3 Gene

Localization for SYN3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SYN3 Gene

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Peripheral membrane protein. Cytoplasmic side. Note=Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SYN3 gene
Compartment Confidence
cytosol 3
plasma membrane 2
extracellular 2
cytoskeleton 2
mitochondrion 2
nucleus 2
peroxisome 1
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for SYN3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008021 synaptic vesicle IEA,TAS 9539796
GO:0014069 postsynaptic density IEA --
GO:0016020 membrane IEA --
GO:0030054 cell junction IEA --
GO:0030672 synaptic vesicle membrane IBA 21873635
genes like me logo Genes that share ontologies with SYN3: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for SYN3 Gene

Pathways & Interactions for SYN3 Gene

genes like me logo Genes that share pathways with SYN3: view

SIGNOR curated interactions for SYN3 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for SYN3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007269 neurotransmitter secretion IEA,IBA 21873635
GO:0032228 regulation of synaptic transmission, GABAergic TAS 15217342
GO:0097091 synaptic vesicle clustering IEA --
GO:0099504 synaptic vesicle cycle IEA --
genes like me logo Genes that share ontologies with SYN3: view

Drugs & Compounds for SYN3 Gene

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  1. Drug products for research

(1) Drugs for SYN3 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Calcium Nutra 6876
genes like me logo Genes that share compounds with SYN3: view

Transcripts for SYN3 Gene

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mRNA/cDNA for SYN3 Gene

8 REFSEQ mRNAs :
11 NCBI additional mRNA sequence :
13 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SYN3

Clone products for research

  • Addgene plasmids for SYN3

Alternative Splicing Database (ASD) splice patterns (SP) for SYN3 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
SP1: - -
SP2: - -
SP3:

Relevant External Links for SYN3 Gene

GeneLoc Exon Structure for
SYN3

Expression for SYN3 Gene

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  1. Primer products for research
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mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SYN3 Gene

mRNA expression in normal human tissues for SYN3 Gene
mRNA expression by GTEx for SYN3 GenemRNA expression by BioGPS for SYN3 Gene

mRNA differential expression in normal tissues according to GTEx for SYN3 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x5.9), Brain - Cortex (x4.8), and Brain - Anterior cingulate cortex (BA24) (x4.5).

Protein differential expression in normal tissues from HIPED for SYN3 Gene

This gene is overexpressed in Frontal cortex (31.7), Brain (25.9), and Fetal Brain (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SYN3 Gene



Protein tissue co-expression partners for SYN3 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SYN3

SOURCE GeneReport for Unigene cluster for SYN3 Gene:

Hs.608750

mRNA Expression by UniProt/SwissProt for SYN3 Gene:

O14994-SYN3_HUMAN
Tissue specificity: Neuron specific. Detected predominantly in brain.

Evidence on tissue expression from TISSUES for SYN3 Gene

  • Nervous system(4.8)
  • Eye(2)
genes like me logo Genes that share expression patterns with SYN3: view

Primer products for research

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for SYN3 Gene

Orthologs for SYN3 Gene

This gene was present in the common ancestor of animals.

Orthologs for SYN3 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia SYN3 30
  • 99.37 (n)
Dog
(Canis familiaris)
 Mammalia -- 31
  • 93 (a)
 OneToMany
SYN3 30
  • 90.2 (n)
-- 31
  • 84 (a)
 OneToMany
Cow
(Bos Taurus)
 Mammalia SYN3 30 31
  • 90.95 (n)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Syn3 30 17 31
  • 87.85 (n)
 OneToOne
Rat
(Rattus norvegicus)
 Mammalia Syn3 30
  • 87.33 (n)
Oppossum
(Monodelphis domestica)
 Mammalia SYN3 31
  • 83 (a)
 OneToOne
Platypus
(Ornithorhynchus anatinus)
 Mammalia -- 31
  • 73 (a)
 OneToMany
-- 31
  • 64 (a)
 OneToMany
-- 31
  • 62 (a)
 OneToMany
Chicken
(Gallus gallus)
 Aves SYN3 30 31
  • 76.42 (n)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia SYN3 31
  • 76 (a)
 OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia syn3 30
  • 70.27 (n)
African clawed frog
(Xenopus laevis)
 Amphibia syn3-A 30
Zebrafish
(Danio rerio)
 Actinopterygii SYN3 31
  • 32 (a)
 OneToOne
Fruit Fly
(Drosophila melanogaster)
 Insecta Syn 30 31 32
  • 54.18 (n)
 OneToMany
African malaria mosquito
(Anopheles gambiae)
 Insecta AgaP_AGAP003318 30
Worm
(Caenorhabditis elegans)
 Secernentea snn-1 30 31
  • 46.46 (n)
 OneToMany
Sea Squirt
(Ciona savignyi)
 Ascidiacea -- 31
  • 65 (a)
 ManyToMany
-- 31
  • 46 (a)
 ManyToMany
Species where no ortholog for SYN3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for SYN3 Gene

ENSEMBL:
Gene Tree for SYN3 (if available)
TreeFam:
Gene Tree for SYN3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SYN3: view image

Paralogs for SYN3 Gene

Paralogs for SYN3 Gene

(3) SIMAP similar genes for SYN3 Gene using alignment to 4 proteins:

  • SYN3_HUMAN
  • A6ZJ82_HUMAN
  • Q17R54_HUMAN
  • Q4TT46_HUMAN
genes like me logo Genes that share paralogs with SYN3: view

Variants for SYN3 Gene

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Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SYN3 Gene

SNP ID Clinical significance and condition Chr 22 pos Variation AA Info Type
837921 Uncertain Significance: not provided 32,802,014(-) C/T
NM_003490.4(SYN3):c.711+62901G>A 		MISSENSE_VARIANT,INTRON
843268 Pathogenic: Retinal dystrophy; not provided 32,802,114(-) C/G
NM_003490.4(SYN3):c.711+62801G>C 		MISSENSE_VARIANT,INTRON
847790 Uncertain Significance: not provided 32,859,298(-) G/A
NM_003490.4(SYN3):c.711+5617C>T 		MISSENSE_VARIANT,INTRON
848924 Uncertain Significance: not provided 32,859,258(-) G/A
NM_003490.4(SYN3):c.711+5657C>T 		MISSENSE_VARIANT,INTRON
854976 Uncertain Significance: not provided 32,858,096(-) C/T
NM_003490.4(SYN3):c.711+6819G>A 		SYNONYMOUS_VARIANT,INTRON

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SYN3 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SYN3 Gene

Variant ID Type Subtype PubMed ID
dgv1313e212 CNV loss 25503493
dgv20e194 CNV deletion 18987734
dgv2454n106 CNV deletion 24896259
dgv4561n100 CNV gain 25217958
esv1085289 CNV insertion 17803354
esv1328555 CNV insertion 17803354
esv1395557 CNV insertion 17803354
esv1664547 CNV deletion 17803354
esv23339 CNV gain 19812545
esv2476031 CNV deletion 19546169
esv2529621 CNV insertion 19546169
esv2638943 CNV deletion 19546169
esv2666744 CNV deletion 23128226
esv2724149 CNV deletion 23290073
esv2724150 CNV deletion 23290073
esv2724152 CNV deletion 23290073
esv2724153 CNV deletion 23290073
esv2724154 CNV deletion 23290073
esv2724155 CNV deletion 23290073
esv2742642 CNV deletion 23290073
esv2762119 CNV gain 21179565
esv3032679 CNV deletion 24192839
esv3356573 CNV duplication 20981092
esv3558080 CNV deletion 23714750
esv3558081 CNV deletion 23714750
esv3568368 CNV loss 25503493
esv3568369 CNV loss 25503493
esv3647609 CNV loss 21293372
esv3647611 CNV loss 21293372
esv3917 CNV loss 18987735
esv6171 CNV loss 19470904
esv998207 CNV deletion 20482838
nsv1056220 CNV gain 25217958
nsv1059368 CNV loss 25217958
nsv1061384 CNV loss 25217958
nsv1064719 CNV loss 25217958
nsv1071789 CNV deletion 25765185
nsv1071790 CNV deletion 25765185
nsv1071791 CNV deletion 25765185
nsv1111234 CNV tandem duplication 24896259
nsv1116956 CNV deletion 24896259
nsv1118950 CNV deletion 24896259
nsv1125230 CNV insertion 24896259
nsv1125755 CNV tandem duplication 24896259
nsv1129230 CNV insertion 24896259
nsv1131657 CNV deletion 24896259
nsv1136670 CNV deletion 24896259
nsv1152679 CNV insertion 26484159
nsv1160750 CNV duplication 26073780
nsv191235 CNV deletion 16902084
nsv191249 CNV insertion 16902084
nsv3599 CNV deletion 18451855
nsv3600 CNV insertion 18451855
nsv459875 CNV gain 19166990
nsv472826 CNV novel sequence insertion 20440878
nsv473313 CNV novel sequence insertion 20440878
nsv507934 OTHER sequence alteration 20534489
nsv588896 CNV gain 21841781
nsv588897 CNV loss 21841781
nsv953073 CNV deletion 24416366
nsv955479 CNV deletion 24416366
nsv955482 CNV deletion 24416366
nsv964625 CNV duplication 23825009

Variation tolerance for SYN3 Gene

Residual Variation Intolerance Score: 45.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.61; 72.53% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SYN3 Gene

Human Gene Mutation Database (HGMD)
SYN3
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SYN3

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SYN3 Gene

Disorders for SYN3 Gene

MalaCards: The human disease database

(14) MalaCards diseases for SYN3 Gene - From: CVR, COP, and GCD

Disorder Aliases PubMed IDs
aland island eye disease
  • aied
seizure disorder
  • seizures
sorsby fundus dystrophy
  • sfd
fundus dystrophy, pseudoinflammatory, recessive form
  • pfd, lavia type
congenital muscular dystrophy-dystroglycanopathy type a6
  • congenital muscular dystrophy-dystroglycanopathy with brain and eye anomalies type a6
- elite association - COSMIC cancer census association via MalaCards
Search SYN3 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for SYN3

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with SYN3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SYN3 Gene

Publications for SYN3 Gene

  1. Association and expression study of synapsin III and schizophrenia. (PMID: 19766700) Chen Q … Chen X (Neuroscience letters 2009) 3 23 41
  2. Association between synapsin III gene promoter SNPs and multiple sclerosis in Basque patients. (PMID: 18755822) Otaegui D … Lopez de Munain A (Multiple sclerosis (Houndmills, Basingstoke, England) 2009) 3 23 41
  3. A third member of the synapsin gene family. (PMID: 9539796) Kao HT … Greengard P (Proceedings of the National Academy of Sciences of the United States of America 1998) 2 3 4
  4. Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. (PMID: 21998595) N'Diaye A … Haiman CA (PLoS genetics 2011) 3 41
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41

ExternalLinks

View latest publications for SYN3 gene in Mastermind

Products for SYN3 Gene

  • Addgene plasmids for SYN3

Sources for SYN3 Gene