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Aliases for SYDE2 Gene
Aliases for SYDE2 Gene
External Ids for SYDE2 Gene
- HGNC: 25841
- Entrez Gene: 84144
- Ensembl: ENSG00000097096
- UniProtKB: Q5VT97
Previous GeneCards Identifiers for SYDE2 Gene
- GC01M085338
- GC01M085623
- GC01M083733
Summaries for SYDE2 Gene
GeneCards Summary for SYDE2 Gene
SYDE2 (Synapse Defective Rho GTPase Homolog 2) is a Protein Coding gene. Diseases associated with SYDE2 include Hypophosphatasia, Adult. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is SYDE1.
UniProtKB/Swiss-Prot Summary for SYDE2 Gene
-
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Additional gene information for SYDE2 Gene
- HGNC(25841)
- Entrez Gene(84144)
- Ensembl(ENSG00000097096)
- UniProtKB(Q5VT97)
- Open Targets Platform(ENSG00000097096)
- Search for SYDE2 at DataMed
- Search for SYDE2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SYDE2 Gene
Genomics for SYDE2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SYDE2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SYDE2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SYDE2
- Top Transcription factor binding sites by QIAGEN in the SYDE2 gene promoter:
-
- CBF(2)
- CBF-A
- CBF-B
- CP1A
- GR
- GR-alpha
- ISGF-3
- NF-Y
- NF-YA
- Nkx2-5
Genomic Locations for SYDE2 Gene
Genomic Locations for SYDE2 Gene
- chr1:85,156,381-85,201,725
- (GRCh38/hg38)
- Size:
- 45,345 bases
- Orientation:
- Minus strand
- chr1:85,622,556-85,666,729
- (GRCh37/hg19)
- Size:
- 44,174 bases
- Orientation:
- Minus strand
Genomic View for SYDE2 Gene
Genes around SYDE2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p22.3 by HGNC
- 1p22.3 by Entrez Gene
- 1p22.3 by Ensembl
SYDE2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SYDE2 Gene
Proteins for SYDE2 Gene
-
Protein details for SYDE2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5VT97-SYDE2_HUMAN
- Recommended name:
- Rho GTPase-activating protein SYDE2
- Protein Accession:
- Q5VT97
- Q5VT96
- Q8NDB8
- Q9H8A6
Protein attributes for SYDE2 Gene
- Size:
- 1194 amino acids
- Molecular mass:
- 133230 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAB14711.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAB14711.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};
Protein Expression for SYDE2 Gene
Post-translational modifications for SYDE2 Gene
Other Protein References for SYDE2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for SYDE2
- Invitrogen Antibodies for SYDE2 (AFLGC-SYDE2)
- antibodies-online: Show 6 available SYDE2 Antibodies ranked by validation data
- Compare Top SYDE2 Antibodies
-
Quality Products:
Protein Products
-
OriGene Purified Proteins for SYDE2
- Search Origene for MassSpec and Protein Over-expression Lysates for SYDE2
- Origene Custom Protein Services for SYDE2
- Novus Biologicals proteins for SYDE2
No data available for DME Specific Peptides for SYDE2 Gene
Domains & Families for SYDE2 Gene
Gene Families for SYDE2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SYDE2 Gene
- InterPro:
- Blocks:
-
- RhoGAP domain
- C2 domain
- ProtoNet:
Suggested Antigen Peptide Sequences for SYDE2 Gene
- GenScript: Design optimal peptide antigens:
-
- Synapse defective protein 1 homolog 2 (SYDE2_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SYDE2 Gene
Function for SYDE2 Gene
Molecular function for SYDE2 Gene
- UniProtKB/Swiss-Prot Function:
- GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Phenotypes From GWAS Catalog for SYDE2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | ISS | -- |
Phenotypes for SYDE2 Gene
- GenomeRNAi human phenotypes for SYDE2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SYDE2 - Select products 50% OFF >
- * SYDE2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SYDE2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SYDE2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SYDE2
miRNA for SYDE2 Gene
- miRTarBase miRNAs that target SYDE2
-
- hsa-miR-378a-5p (MIRT043965)
- hsa-miR-23b-3p (MIRT046326)
- hsa-miR-182-5p (MIRT553851)
- hsa-miR-6809-5p (MIRT553852)
- hsa-miR-571 (MIRT553853)
- hsa-miR-136-5p (MIRT553854)
- hsa-miR-6814-5p (MIRT553855)
- hsa-miR-4733-5p (MIRT553856)
- hsa-miR-4715-5p (MIRT553857)
- hsa-miR-31-5p (MIRT553858)
- hsa-miR-6510-3p (MIRT714024)
- hsa-miR-6888-3p (MIRT714025)
- hsa-miR-4522 (MIRT714026)
- hsa-miR-3120-5p (MIRT714027)
- hsa-miR-372-5p (MIRT714028)
- hsa-miR-371a-5p (MIRT714029)
- hsa-miR-616-5p (MIRT714030)
- hsa-miR-373-5p (MIRT714031)
- hsa-miR-371b-5p (MIRT714032)
- hsa-miR-3065-5p (MIRT714033)
- hsa-miR-3613-3p (MIRT714034)
- hsa-miR-3664-5p (MIRT714035)
- hsa-miR-3529-3p (MIRT714036)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SYDE2
- Browse OriGene Inhibitory RNA Products For SYDE2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SYDE2
Clone Products
- Applied Biological Materials (abm): Clones for SYDE2 - Select products 50% OFF >
- * SYDE2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SYDE2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SYDE2
Cell Line Products
-
Horizon Cell Lines for SYDE2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SYDE2 Gene
Localization for SYDE2 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 2 |
| golgi apparatus | 1 |
- Golgi apparatus (2)
- Nucleoli (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for SYDE2 Gene
Pathways & Interactions for SYDE2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | p75 NTR receptor-mediated signalling |
.36
|
|
| 2 | Signaling by GPCR | ||
| 3 | Signaling by Rho GTPases | ||
Pathways by source for SYDE2 Gene
3 Reactome pathways for SYDE2 Gene
Interacting Proteins for SYDE2 Gene
GPS-Prot Interaction Network for SYDE2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0016477 | cell migration | IDA | 27917469 |
| GO:0051056 | regulation of small GTPase mediated signal transduction | TAS | -- |
| GO:0090630 | activation of GTPase activity | ISS | -- |
Transcripts for SYDE2 Gene
mRNA/cDNA for SYDE2 Gene
- 1 REFSEQ mRNAs :
- 3 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000234668 3000 nts (view in UCSC)
- ENST00000341460 5466 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SYDE2 - Select products 50% OFF >
- * SYDE2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SYDE2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SYDE2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SYDE2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SYDE2
- Browse OriGene Inhibitory RNA Products For SYDE2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SYDE2
Clone Products
- Applied Biological Materials (abm): Clones for SYDE2 - Select products 50% OFF >
- * SYDE2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SYDE2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SYDE2
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||
| SP2: | |||||||||||||||
| SP3: | - |
Relevant External Links for SYDE2 Gene
- GeneLoc Exon Structure for
- SYDE2
Expression for SYDE2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Yolk Sac (Extraembryonic Tissues)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
-
Blood (Cardiovascular System)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
mRNA differential expression in normal tissues according to GTEx for SYDE2 Gene
This gene is overexpressed in Colon - Sigmoid (x5.9) and Esophagus - Muscularis (x4.8).
This gene is overexpressed in Fetal heart (63.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SYDE2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SYDE2
SOURCE GeneReport for Unigene cluster for SYDE2 Gene:
Hs.670497Evidence on tissue expression from TISSUES for SYDE2 Gene
- Thyroid gland(4.2)
- Lymph node(4)
- Lung(3.9)
- Intestine(3.6)
- Kidney(2.5)
Primer Products
-
OriGene qPCR primer pairs for SYDE2
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SYDE2 Gene
Orthologs for SYDE2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SYDE2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SYDE2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SYDE2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Syde2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Syde2 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SYDE2 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | SYDE2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | SYDE2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SYDE2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | syde2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | SYDE2 31 |
|
OneToOne | |
| LOC100333199 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | RhoGAP100F 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | syd-1 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | BEM2 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.767 31 |
|
OneToMany |
- Species where no ortholog for SYDE2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for SYDE2 Gene
- ENSEMBL:
- Gene Tree for SYDE2 (if available)
- TreeFam:
- Gene Tree for SYDE2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SYDE2: view image
Paralogs for SYDE2 Gene
Variants for SYDE2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SYDE2 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 711053 | Likely Benign: not provided | 85,190,219(-) | C/T | MISSENSE_VARIANT | |
| 713881 | Benign: not provided | 85,190,190(-) | C/T | SYNONYMOUS_VARIANT | |
| 767681 | Benign: not provided | 85,183,190(-) | G/C | MISSENSE_VARIANT | |
| 781663 | Benign: not provided | 85,190,726(-) | A/G | MISSENSE_VARIANT | |
| 783290 | Benign: not provided | 85,190,686(-) | A/G | MISSENSE_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv347n54 | CNV | loss | 21841781 |
| dgv348n54 | CNV | loss | 21841781 |
| dgv349n54 | CNV | gain | 21841781 |
| dgv350n54 | CNV | gain | 21841781 |
| dgv351n54 | CNV | gain | 21841781 |
| esv23473 | CNV | loss | 19812545 |
| esv3329522 | CNV | insertion | 20981092 |
| esv34165 | CNV | loss | 18971310 |
| nsv546706 | CNV | gain+loss | 21841781 |
| nsv546709 | CNV | loss | 21841781 |
| nsv830459 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
82.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.24;
85.01% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SYDE2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SYDE2 Gene
Disorders for SYDE2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hypophosphatasia, adult |
|
|
Search SYDE2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SYDE2
No data available for UniProtKB/Swiss-Prot and Genatlas for SYDE2 Gene
Publications for SYDE2 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3
- E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. (PMID: 29676528) Khanna R … Parnaik VK (The FEBS journal 2018) 3
- Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion. (PMID: 27917469) Lo HF … Chen H (The Journal of pathology 2017) 3
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
ExternalLinks
Products for SYDE2 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SYDE2
- Search Origene for MassSpec and Protein Over-expression Lysates for SYDE2
- Origene Custom Protein Services for SYDE2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SYDE2
- Browse OriGene Inhibitory RNA Products For SYDE2
- OriGene qPCR primer pairs for SYDE2
- OriGene CRISPR knockouts for SYDE2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SYDE2
- Sino Biological Human cDNA Clone for SYDE2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SYDE2
- Novus Biologicals proteins for SYDE2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for SYDE2 (AFLGC-SYDE2)
- VectorBuilder Custom and pre-made DNA vectors for SYDE2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SYDE2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SYDE2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SYDE2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SYDE2
- antibodies-online: Show 6 available SYDE2 Antibodies ranked by validation data
- Compare Top SYDE2 Antibodies
- Quality Products:
- antibodies-online: Search results for available SYDE2 related products ranked by validation data
- antibodies-online: Search results for available SYDE2 related products ranked by validation data
- Horizon Cell Lines for SYDE2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SYDE2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SYDE2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SYDE2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SYDE2
Sources for SYDE2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB