Aliases for SWAP70 Gene
External Ids for SWAP70 Gene
Previous GeneCards Identifiers for SWAP70 Gene
GeneCards Summary for SWAP70 Gene
SWAP70 (Switching B Cell Complex Subunit SWAP70) is a Protein Coding gene. Among its related pathways are NF-kappaB Signaling. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is DEF6.
UniProtKB/Swiss-Prot for SWAP70 Gene
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).