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Aliases for SUPT20HL2 Gene

Aliases for SUPT20HL2 Gene

  • SUPT20H Like 2 2 3 5
  • Family With Sequence Similarity 48, Member B2 2 3
  • FAM48B2 3 4
  • Suppressor Of Ty 20 Homolog (S. Cerevisiae)-Like 2 2
  • Putative Transcription Factor SPT20 Homolog-Like 2 3
  • Family With Sequence Similarity 48, Member B1 3
  • SPT20 Homolog, SAGA Complex Component Like 2 2
  • SPT20 Homolog, SAGA Complex Component-Like 2 3
  • Suppressor Of Ty 20 Homolog-Like 2 3
  • Putative Protein FAM48B2 3
  • FAM48B1 3

External Ids for SUPT20HL2 Gene

Previous HGNC Symbols for SUPT20HL2 Gene

  • FAM48B2

Summaries for SUPT20HL2 Gene

GeneCards Summary for SUPT20HL2 Gene

SUPT20HL2 (SUPT20H Like 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transcription cofactor activity.

Additional gene information for SUPT20HL2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SUPT20HL2 Gene

Genomics for SUPT20HL2 Gene

GeneHancer (GH) Regulatory Elements for SUPT20HL2 Gene

Promoters and enhancers for SUPT20HL2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI024229 Enhancer 1.1 Ensembl ENCODE 0.2 +82.6 82595 2.4 PKNOX1 ATF1 ATF7 FOS ZNF592 MAFF GMEB1 SMARCA4 NBN NR2C1 ZFX SUPT20HL2 ZFX-AS1
GH0XI024242 Enhancer 1 Ensembl ENCODE 0.2 +69.3 69318 3.6 ARID4B RAD21 RFX5 ZNF366 ZNF143 FOS IKZF2 RUNX3 ZNF362 SMARCC1 ZFX ZFX-AS1 ENSG00000201407 KLHL15 SUPT20HL2
GH0XI024282 Enhancer 0.6 Ensembl ENCODE 0.3 +30.4 30358 1.8 ZNF189 RUNX3 NR2F2 SUPT20HL2 ZFX-AS1
GH0XI024260 Enhancer 0.8 Ensembl ENCODE 0.2 +52.2 52161 1.3 L3MBTL2 MAX GABPA ZNF121 ZNF148 HNF4A PRDM1 SPI1 SUPT20HL2 ZFX-AS1
GH0XI024252 Enhancer 0.7 ENCODE 0.2 +60.1 60076 1.3 SOX13 FOXA2 CEBPG ZNF48 RAD21 YY1 HNF4G HOMEZ GATAD2A ZNF362 SUPT20HL2 ZFX-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SUPT20HL2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SUPT20HL2 Gene

Genomic Locations for SUPT20HL2 Gene
chrX:24,310,862-24,313,315
(GRCh38/hg38)
Size:
2,454 bases
Orientation:
Minus strand
chrX:24,328,979-24,331,432
(GRCh37/hg19)

Genomic View for SUPT20HL2 Gene

Genes around SUPT20HL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SUPT20HL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SUPT20HL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SUPT20HL2 Gene

Proteins for SUPT20HL2 Gene

  • Protein details for SUPT20HL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7V6-SP202_HUMAN
    Recommended name:
    Putative transcription factor SPT20 homolog-like 2
    Protein Accession:
    P0C7V6

    Protein attributes for SUPT20HL2 Gene

    Size:
    817 amino acids
    Molecular mass:
    87541 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SUPT20HL2 Gene

Post-translational modifications for SUPT20HL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SUPT20HL2 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for SUPT20HL2 Gene

Domains & Families for SUPT20HL2 Gene

Protein Domains for SUPT20HL2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SUPT20HL2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7V6

UniProtKB/Swiss-Prot:

SP202_HUMAN :
  • Belongs to the SPT20 family.
Family:
  • Belongs to the SPT20 family.
genes like me logo Genes that share domains with SUPT20HL2: view

No data available for Gene Families for SUPT20HL2 Gene

Function for SUPT20HL2 Gene

Phenotypes From GWAS Catalog for SUPT20HL2 Gene

Gene Ontology (GO) - Molecular Function for SUPT20HL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003712 transcription cofactor activity IEA --
genes like me logo Genes that share ontologies with SUPT20HL2: view

Phenotypes for SUPT20HL2 Gene

GenomeRNAi human phenotypes for SUPT20HL2:
genes like me logo Genes that share phenotypes with SUPT20HL2: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SUPT20HL2 Gene

Localization for SUPT20HL2 Gene

Gene Ontology (GO) - Cellular Components for SUPT20HL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000124 SAGA complex IEA --
GO:0005615 extracellular space HDA 23580065
genes like me logo Genes that share ontologies with SUPT20HL2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SUPT20HL2 Gene

Pathways & Interactions for SUPT20HL2 Gene

SuperPathways for SUPT20HL2 Gene

No Data Available

Interacting Proteins for SUPT20HL2 Gene

Gene Ontology (GO) - Biological Process for SUPT20HL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903506 regulation of nucleic acid-templated transcription IEA --
genes like me logo Genes that share ontologies with SUPT20HL2: view

No data available for Pathways by source and SIGNOR curated interactions for SUPT20HL2 Gene

Drugs & Compounds for SUPT20HL2 Gene

No Compound Related Data Available

Transcripts for SUPT20HL2 Gene

mRNA/cDNA for SUPT20HL2 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SUPT20HL2 Gene

Suppressor of Ty 20 homolog (S. cerevisiae)-like 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SUPT20HL2 Gene

No ASD Table

Relevant External Links for SUPT20HL2 Gene

GeneLoc Exon Structure for
SUPT20HL2
ECgene alternative splicing isoforms for
SUPT20HL2

Expression for SUPT20HL2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SUPT20HL2 Gene

mRNA differential expression in normal tissues according to GTEx for SUPT20HL2 Gene

This gene is overexpressed in Testis (x14.0), Fallopian Tube (x9.2), and Uterus (x4.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SUPT20HL2 Gene



NURSA nuclear receptor signaling pathways regulating expression of SUPT20HL2 Gene:

SUPT20HL2

SOURCE GeneReport for Unigene cluster for SUPT20HL2 Gene:

Hs.716893
genes like me logo Genes that share expression patterns with SUPT20HL2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SUPT20HL2 Gene

Orthologs for SUPT20HL2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for SUPT20HL2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM48B2 33
  • 98.82 (n)
Species where no ortholog for SUPT20HL2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SUPT20HL2 Gene

ENSEMBL:
Gene Tree for SUPT20HL2 (if available)
TreeFam:
Gene Tree for SUPT20HL2 (if available)

Paralogs for SUPT20HL2 Gene

(3) SIMAP similar genes for SUPT20HL2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SUPT20HL2: view

No data available for Paralogs for SUPT20HL2 Gene

Variants for SUPT20HL2 Gene

Sequence variations from dbSNP and Humsavar for SUPT20HL2 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1000478291 -- 24,314,292(-) AAA/AA upstream_transcript_variant
rs1001486927 -- 24,311,960(-) T/C/G coding_sequence_variant, synonymous_variant
rs1002457144 -- 24,310,698(-) C/T downstream_transcript_variant
rs1002900032 -- 24,310,368(-) G/A downstream_transcript_variant
rs1004300572 -- 24,310,859(-) G/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SUPT20HL2 Gene

Variant ID Type Subtype PubMed ID
nsv483074 CNV loss 15286789

Additional Variant Information for SUPT20HL2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SUPT20HL2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SUPT20HL2 Gene

Disorders for SUPT20HL2 Gene

Additional Disease Information for SUPT20HL2

No disorders were found for SUPT20HL2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SUPT20HL2 Gene

Publications for SUPT20HL2 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 58
  2. Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. (PMID: 23580065) Pieragostino D … Del Boccio P (Molecular bioSystems 2013) 3 58

Products for SUPT20HL2 Gene

Sources for SUPT20HL2 Gene

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