Aliases for SUPT20HL1 Gene

Aliases for SUPT20HL1 Gene

  • SUPT20H Like 1 2 3 5
  • Family With Sequence Similarity 48, Member B1 2 3
  • SPT20 Homolog, SAGA Complex Component Like 1 2 3
  • Transcription Factor SPT20 Homolog-Like 1 3 4
  • FAM48B1 3 4
  • Similar To Transcription Factor (P38 Interacting Protein) 2
  • Suppressor Of Ty 20 Homolog (S. Cerevisiae)-Like 1 2
  • Suppressor Of Ty 20 Homolog-Like 1 3
  • SPT20L 3

External Ids for SUPT20HL1 Gene

Previous HGNC Symbols for SUPT20HL1 Gene

  • FAM48B1

Previous GeneCards Identifiers for SUPT20HL1 Gene

  • GC0XP024380

Summaries for SUPT20HL1 Gene

GeneCards Summary for SUPT20HL1 Gene

SUPT20HL1 (SUPT20H Like 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transcription coregulator activity.

Additional gene information for SUPT20HL1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SUPT20HL1 Gene

Genomics for SUPT20HL1 Gene

GeneHancer (GH) Regulatory Elements for SUPT20HL1 Gene

Promoters and enhancers for SUPT20HL1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ024364 Enhancer 0.3 Ensembl 500.7 +1.3 1340 0.2 OSR2 5MWI_A-201 SUPT20HL1 lnc-PDK3-2
GH0XJ024363 Enhancer 0.2 Ensembl 500.7 +0.8 840 0.4 5MWI_A-201 SUPT20HL1 lnc-PDK3-2
GH0XJ024365 Enhancer 0.3 Ensembl 0.7 +2.1 2140 1 OSR2 ZBTB44 5MWI_A-201 lnc-PDK3-2 SUPT20HL1 RF00017-8244
GH0XJ024356 Enhancer 0.4 Ensembl 0.4 -5.9 -5860 1 FOS GATA2 JUN SUPT20HL1 RF00017-8243
GH0XJ024355 Enhancer 0.3 Ensembl 0.4 -7.6 -7560 0.4 FOS SUPT20HL1 RF00017-8243
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SUPT20HL1 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SUPT20HL1

Genomic Locations for SUPT20HL1 Gene

Genomic Locations for SUPT20HL1 Gene
chrX:24,362,761-24,365,424
(GRCh38/hg38)
Size:
2,664 bases
Orientation:
Plus strand
chrX:24,380,878-24,383,541
(GRCh37/hg19)
Size:
2,664 bases
Orientation:
Plus strand

Genomic View for SUPT20HL1 Gene

Genes around SUPT20HL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SUPT20HL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SUPT20HL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SUPT20HL1 Gene

Proteins for SUPT20HL1 Gene

  • Protein details for SUPT20HL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q3ZLR7-SP201_HUMAN
    Recommended name:
    Transcription factor SPT20 homolog-like 1
    Protein Accession:
    Q3ZLR7

    Protein attributes for SUPT20HL1 Gene

    Size:
    823 amino acids
    Molecular mass:
    89431 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SUPT20HL1 Gene

Post-translational modifications for SUPT20HL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SUPT20HL1 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for SUPT20HL1 Gene

Domains & Families for SUPT20HL1 Gene

Protein Domains for SUPT20HL1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SUPT20HL1 Gene

GenScript: Design optimal peptide antigens:
  • Protein FAM48B1 (F48B1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q3ZLR7

UniProtKB/Swiss-Prot:

SP201_HUMAN :
  • Belongs to the SPT20 family.
Family:
  • Belongs to the SPT20 family.
genes like me logo Genes that share domains with SUPT20HL1: view

No data available for Gene Families for SUPT20HL1 Gene

Function for SUPT20HL1 Gene

Phenotypes From GWAS Catalog for SUPT20HL1 Gene

Gene Ontology (GO) - Molecular Function for SUPT20HL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003712 transcription coregulator activity IEA --
genes like me logo Genes that share ontologies with SUPT20HL1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SUPT20HL1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SUPT20HL1 Gene

Localization for SUPT20HL1 Gene

Gene Ontology (GO) - Cellular Components for SUPT20HL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000124 SAGA complex IBA 21873635
genes like me logo Genes that share ontologies with SUPT20HL1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SUPT20HL1 Gene

Pathways & Interactions for SUPT20HL1 Gene

PathCards logo

SuperPathways for SUPT20HL1 Gene

No Data Available

Interacting Proteins for SUPT20HL1 Gene

Selected Interacting proteins: Q3ZLR7-SP201_HUMAN for SUPT20HL1 Gene via IID

Symbol External ID(s) Details
CUL1
;

Gene Ontology (GO) - Biological Process for SUPT20HL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IBA 21873635
genes like me logo Genes that share ontologies with SUPT20HL1: view

No data available for Pathways by source and SIGNOR curated interactions for SUPT20HL1 Gene

Drugs & Compounds for SUPT20HL1 Gene

No Compound Related Data Available

Transcripts for SUPT20HL1 Gene

mRNA/cDNA for SUPT20HL1 Gene

1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SUPT20HL1

Alternative Splicing Database (ASD) splice patterns (SP) for SUPT20HL1 Gene

No ASD Table

Relevant External Links for SUPT20HL1 Gene

GeneLoc Exon Structure for
SUPT20HL1

Expression for SUPT20HL1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SUPT20HL1 Gene

mRNA differential expression in normal tissues according to GTEx for SUPT20HL1 Gene

This gene is overexpressed in Fallopian Tube (x5.5), Cervix - Ectocervix (x5.3), and Uterus (x4.0).

Protein differential expression in normal tissues from HIPED for SUPT20HL1 Gene

This gene is overexpressed in Cervix (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SUPT20HL1 Gene



Protein tissue co-expression partners for SUPT20HL1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SUPT20HL1

SOURCE GeneReport for Unigene cluster for SUPT20HL1 Gene:

Hs.717243
genes like me logo Genes that share expression patterns with SUPT20HL1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SUPT20HL1 Gene

Orthologs for SUPT20HL1 Gene

Evolution for SUPT20HL1 Gene

ENSEMBL:
Gene Tree for SUPT20HL1 (if available)
TreeFam:
Gene Tree for SUPT20HL1 (if available)

No data available for Orthologs for SUPT20HL1 Gene

Paralogs for SUPT20HL1 Gene

(3) SIMAP similar genes for SUPT20HL1 Gene using alignment to 1 proteins:

  • SP201_HUMAN
genes like me logo Genes that share paralogs with SUPT20HL1: view

No data available for Paralogs for SUPT20HL1 Gene

Variants for SUPT20HL1 Gene

Additional dbSNP identifiers (rs#s) for SUPT20HL1 Gene

Structural Variations from Database of Genomic Variants (DGV) for SUPT20HL1 Gene

Variant ID Type Subtype PubMed ID
nsv483074 CNV loss 15286789

Additional Variant Information for SUPT20HL1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SUPT20HL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SUPT20HL1 Gene

Disorders for SUPT20HL1 Gene

Additional Disease Information for SUPT20HL1

No disorders were found for SUPT20HL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SUPT20HL1 Gene

Publications for SUPT20HL1 Gene

  1. The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes. (PMID: 19114550) Nagy Z … Tora L (Molecular and cellular biology 2009) 2 3 54
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 54
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  4. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett EJ … Harper JW (Cell 2010) 3 54

Products for SUPT20HL1 Gene

Sources for SUPT20HL1 Gene