Aliases for SULT4A1 Gene
External Ids for SULT4A1 Gene
Previous GeneCards Identifiers for SULT4A1 Gene
This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia. [provided by RefSeq, Jul 2008]
GeneCards Summary for SULT4A1 Gene
SULT4A1 (Sulfotransferase Family 4A Member 1) is a Protein Coding gene. Diseases associated with SULT4A1 include Mixed Receptive-Expressive Language Disorder and Schizoaffective Disorder. Among its related pathways are Sulfation Biotransformation Reaction and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include sulfotransferase activity. An important paralog of this gene is SULT1A4.
UniProtKB/Swiss-Prot Summary for SULT4A1 Gene
Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS.