Free for academic non-profit institutions. Other users need a Commercial license
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activ... See more...
Aliases for SULT1A3 Gene
Aliases for SULT1A3 Gene
- Sulfotransferase Family 1A Member 3 2 3 5
- Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 3 2 3
- Catecholamine-Sulfating Phenol Sulfotransferase 3 4
- Placental Estrogen Sulfotransferase 3 4
- Aryl Sulfotransferase 1A3/1A4 3 4
- Sulfotransferase 1A3 3 4
- TL-PST 3 4
- HAST3 3 4
- M-PST 3 4
- ST1A3 3 4
- STM 3 4
- Thermolabile (Monoamine, M Form) Phenol Sulfotransferase 3
- Monoamine-Sulfating Phenol Sulfotransferase 4
- Monoamine-Sulfating Phenosulfotransferase 3
- Sulfotransferase, Monoamine-Preferring 4
- Thermolabile Phenol Sulfotransferase 4
- Dopamine-Specific Sulfotransferase 3
- Phenol Sulfotransferase 1A5 3
- Sulfotransferase 1A3/1A4 4
- Sulfotransferase 1A4 3
- ST1A3/ST1A4 3
- Sulfokinase 3
- EC 2.8.2.1 4
- ST1A4 3
- ST1A5 3
- HAST 3
External Ids for SULT1A3 Gene
- HGNC: 11455
- Entrez Gene: 6818
- Ensembl: ENSG00000261052
- OMIM: 600641
- UniProtKB: P0DMM9
Previous HGNC Symbols for SULT1A3 Gene
- STM
Previous GeneCards Identifiers for SULT1A3 Gene
- GC16M029624
- GC16P030599
- GC16P030203
- GC16P030241
- GC16P030112
- GC16P030206
- GC16P027869
- GC16P030209
- GC16P030213
- GC16P030217
Summaries for SULT1A3 Gene
-
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. This gene is the most centromeric of the four sulfotransferase genes. Read-through transcription exists between this gene and the upstream SLX1A (SLX1 structure-specific endonuclease subunit homolog A) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq, Nov 2010]
GeneCards Summary for SULT1A3 Gene
SULT1A3 (Sulfotransferase Family 1A Member 3) is a Protein Coding gene. Diseases associated with SULT1A3 include Ceroid Lipofuscinosis, Neuronal, 3 and Dengue Shock Syndrome. Among its related pathways are Acetaminophen Pathway (therapeutic doses), Pharmacokinetics and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include sulfotransferase activity and aryl sulfotransferase activity. An important paralog of this gene is SULT1A4.
UniProtKB/Swiss-Prot Summary for SULT1A3 Gene
-
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.
Additional gene information for SULT1A3 Gene
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SULT1A3 Gene
Genomics for SULT1A3 Gene
GeneHancer (GH) Regulatory Elements for SULT1A3 Gene
Promoters and enhancers for SULT1A3 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH16J030208 | Promoter/Enhancer | 0.8 | EPDnew Ensembl dbSUPER | 750.6 | +0.3 | 273 | 0.6 | SULT1A3 ENSG00000278887 SLX1A-SULT1A3 | ||
| GH16J030204 | Promoter/Enhancer | 0.5 | EPDnew dbSUPER | 750.6 | +0.6 | 606 | 0.1 | SULT1A3 ENSG00000278887 SLX1A-SULT1A3 | ||
| GH16J030200 | Promoter/Enhancer | 0.5 | EPDnew dbSUPER | 750.6 | +1.5 | 1533 | 0.1 | SULT1A3 ENSG00000278887 SLX1A-SULT1A3 | ||
| GH16J030199 | Promoter/Enhancer | 0.5 | Ensembl dbSUPER | 750.6 | -0.3 | -327 | 0.2 | SULT1A3 BOLA2B SLX1A-SULT1A3 | ||
| GH16J030198 | Enhancer | 0.2 | dbSUPER | 750.6 | -0.7 | -743 | 0.6 | SULT1A3 BOLA2B SLX1A-SULT1A3 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SULT1A3 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the SULT1A3 gene promoter:
-
- CREB
- deltaCREB
- p300
Genomic Locations for SULT1A3 Gene
Genomic Locations for SULT1A3 Gene
- chr16:30,199,228-30,204,329
- (GRCh38/hg38)
- Size:
- 5,102 bases
- Orientation:
- Plus strand
- chr16:30,205,754-30,215,650
- (GRCh37/hg19)
- Size:
- 9,897 bases
- Orientation:
- Plus strand
Genomic View for SULT1A3 Gene
Genes around SULT1A3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p11.2 by HGNC
- 16p11.2 by Entrez Gene
- 16p11.2 by Ensembl
SULT1A3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SULT1A3 Gene
Proteins for SULT1A3 Gene
-
Protein details for SULT1A3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P0DMM9-ST1A3_HUMAN
- Recommended name:
- Sulfotransferase 1A3
- Protein Accession:
- P0DMM9
- B4DNV0
- O95603
- P50224
- Q1ET66
- Q6ZWJ5
Protein attributes for SULT1A3 Gene
- Size:
- 295 amino acids
- Molecular mass:
- 34196 Da
- Quaternary structure:
-
- Homodimer.
Protein Expression for SULT1A3 Gene
Post-translational modifications for SULT1A3 Gene
- The N-terminus is blocked.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for SULT1A3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Creative Biolabs
- Recombinant Anti-Human SULT1A3 Antibody
- Recombinant Anti-Human SULT1A3 Antibody Fab Fragment
- Rabbit Anti-SULT1A3 Recombinant Antibody (EPR3720(2))
- Mouse Anti-SULT1A3 Recombinant Antibody (CBXS-2780)
- Recombinant Mouse Anti-Human SULT1A3 Antibody (clone 1B10)
- Mouse Anti-SULT1A3 Recombinant Antibody (CBXS-2362)
- Mouse Anti-SULT1A3 Recombinant Antibody (CBXS-2683)
- Mouse Anti-SULT1A3 Recombinant Antibody (CBXS-2361)
- Hi-Affi™ Recombinant Rabbit Anti-SULT1A3 Monoclonal Antibody (DS3459AB)
- Novus Biologicals Antibodies for SULT1A3
-
Abcam antibodies for SULT1A3
- Invitrogen Antibodies for SULT1A3 (AFLGC-SULT1A3)
-
Biorbyt antibodies for SULT1A3
-
Santa Cruz Biotechnology (SCBT) Antibodies for SULT1A3
- Sino Biological Antibodies for SULT1A3
Protein Products
- Creative Biomart Recombinant Human SULT1A3 293 Cell Lysate
- Search Origene for MassSpec and Protein Over-expression Lysates for SULT1A3
- Origene Custom Protein Services for SULT1A3
- Novus Biologicals lysates for SULT1A3
- Sino Biological Recombinant Proteins for SULT1A3
- Browse Sino Biological Cell Lysates
-
Abcam proteins for SULT1A3
No data available for DME Specific Peptides for SULT1A3 Gene
Domains & Families for SULT1A3 Gene
Gene Families for SULT1A3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for SULT1A3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SULT1A3 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ16185 fis, clone BRTHA2005864, highly similar to Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Q1ET61_HUMAN)
- Phenol sulfotransferase 1A5*5 (Q1ET62_HUMAN)
- Phenol sulfotransferase 1A5*4 (Q1ET63_HUMAN)
- Phenol sulfotransferase 1A5*3 (Q1ET64_HUMAN)
- Phenol sulfotransferase 1A5*2 (Q1ET65_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P0DMM9- Family:
-
- Belongs to the sulfotransferase 1 family.
Function for SULT1A3 Gene
Molecular function for SULT1A3 Gene
- UniProtKB/Swiss-Prot Function:
- Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=3'-phosphoadenylyl sulfate + a phenol = a phenyl sulfate + adenosine 3',5'-bisphosphate + H(+); Xref=Rhea:RHEA:12164, ChEBI:CHEBI:15378, ChEBI:CHEBI:33853, ChEBI:CHEBI:58339, ChEBI:CHEBI:58343, ChEBI:CHEBI:140317; EC=2.8.2.1;.
- GENATLAS Biochemistry:
- aryl (phenol) sulfotransferase,thermolabile,monoamine neurotransmitters sulfating preferring,cytosolic
Enzyme Numbers (IUBMB) for SULT1A3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004062 | aryl sulfotransferase activity | IMP | 9855620 |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0008146 | sulfotransferase activity | IDA,IEA | 20056724 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0043199 | sulfate binding | IDA | 10543947 |
Phenotypes for SULT1A3 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for SULT1A3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SULT1A3
- Applied Biological Materials (abm): CRISPR Clones for SULT1A3 - Select products 50% OFF >
- * SULT1A3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SULT1A3 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for SULT1A3
miRNA for SULT1A3 Gene
- miRTarBase miRNAs that target SULT1A3
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SULT1A3
- Browse OriGene Inhibitory RNA Products For SULT1A3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SULT1A3
Clone Products
- Sino Biological Human cDNA Clone for SULT1A3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SULT1A3
- Applied Biological Materials (abm): Clones for SULT1A3 - Select products 50% OFF >
- * SULT1A3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SULT1A3 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for SULT1A3
No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SULT1A3 Gene
Localization for SULT1A3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SULT1A3 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 4 |
| extracellular | 2 |
| plasma membrane | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for SULT1A3 Gene
Pathways & Interactions for SULT1A3 Gene
Pathways by source for SULT1A3 Gene
8 Reactome pathways for SULT1A3 Gene
3 PharmGKB pathways for SULT1A3 Gene
1 KEGG pathway for SULT1A3 Gene
2 GeneGo (Thomson Reuters) pathways for SULT1A3 Gene
Interacting Proteins for SULT1A3 Gene
Selected Interacting proteins:
P0DMM9-ST1A3_HUMAN
ENSP00000378570
for SULT1A3 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SULT1A3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006068 | ethanol catabolic process | IDA | 23207770 |
| GO:0006584 | catecholamine metabolic process | IEA | -- |
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0006805 | xenobiotic metabolic process | IDA | 20056724 |
| GO:0007212 | dopamine receptor signaling pathway | IDA | 24136195 |
No data available for SIGNOR curated interactions for SULT1A3 Gene
Drugs & Compounds for SULT1A3 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Acetaminophen | Approved | Pharma | Enzyme, substrate | 1258 | ||
| Phenol | Approved, Experimental | Pharma | 65 | |||
| Morphine | Approved, Investigational | Pharma | Full agonist, Agonist, Partial agonist | 1307 | ||
| Tapentadol | Approved | Pharma | 73 | |||
| Tramadol | Approved, Investigational | Pharma | 317 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| (+)-Catechin 6-C-glucoside |
|
105371-27-5 |
|
|||
| (+)-Catechin 8-C-glucoside |
|
105371-26-4 |
|
|||
| (1E)-1-(4-hydroxyphenyl)pent-1-en-3-one |
|
|
|
|||
| (2E)-1-(3-hydroxyphenyl)-3-phenylprop-2-en-1-one |
|
|
|
|||
| (2E)-1-(4-hydroxyphenyl)-3-phenylprop-2-en-1-one |
|
|
|
Drug Products
- Creative Biomart Recombinant Human SULT1A3 293 Cell Lysate
Transcripts for SULT1A3 Gene
mRNA/cDNA for SULT1A3 Gene
- (3) REFSEQ mRNAs :
- (19) Additional mRNA sequences :
- (49) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000338971 1097 bps (ENST00000338971.9)
- ENST00000395138 1326 bps (ENST00000395138.6)
- ENST00000561533 782 bps (ENST00000561533.1)
- ENST00000561549 833 bps (ENST00000561549.1)
- ENST00000562257 437 bps (ENST00000562257.5)
CRISPR Products
-
OriGene CRISPR knockouts for SULT1A3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SULT1A3
- Applied Biological Materials (abm): CRISPR Clones for SULT1A3 - Select products 50% OFF >
- * SULT1A3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SULT1A3 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for SULT1A3
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SULT1A3
- Browse OriGene Inhibitory RNA Products For SULT1A3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SULT1A3
Clone Products
- Sino Biological Human cDNA Clone for SULT1A3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SULT1A3
- Applied Biological Materials (abm): Clones for SULT1A3 - Select products 50% OFF >
- * SULT1A3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SULT1A3 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Expression for SULT1A3 Gene
This gene is overexpressed in Platelet (8.4), Lymph node (7.6), and Fetal gut (7.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SULT1A3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of SULT1A3 Gene:
SULT1A3SOURCE GeneReport for Unigene cluster for SULT1A3 Gene:
Hs.460558mRNA Expression by UniProt/SwissProt for SULT1A3 Gene:
P0DMM9-ST1A3_HUMAN
Tissue specificity:
Liver, colon, kidney, lung, brain, spleen, small intestine, placenta and leukocyte.
Evidence on tissue expression from TISSUES for SULT1A3 Gene
- Liver(4.6)
- Kidney(4.5)
- Blood(4.4)
- Nervous system(4.4)
- Lung(4.2)
- Pancreas(4)
- Intestine(2.3)
- Heart(2.1)
Primer Products
-
OriGene qPCR primer pairs for SULT1A3
-
OriGene qPCR primer pairs and template standards for SULT1A3
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SULT1A3 Gene
Orthologs for SULT1A3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC454364 32 |
|
||
| -- 33 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | SULT1A1 33 |
|
OneToMany | |
| cow (Bos Taurus) |
Mammalia | SULT1A1 33 |
|
OneToMany | |
| mouse (Mus musculus) |
Mammalia | Sult1a1 33 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 33 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 33 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 33 |
|
ManyToMany | |
| -- 33 |
|
ManyToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | CG5428 34 |
|
|
|
| CG5431 34 |
|
|
|||
| CG16733 34 |
|
|
- Species where no ortholog for SULT1A3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for SULT1A3 Gene
- ENSEMBL:
- Gene Tree for SULT1A3 (if available)
- TreeFam:
- Gene Tree for SULT1A3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SULT1A3: view image
Paralogs for SULT1A3 Gene
Paralogs for SULT1A3 Gene
(13) SIMAP similar genes for SULT1A3 Gene using alignment to 3 proteins:
- ST1A3_HUMAN
- H3BPL6_HUMAN
- H3BRT0_HUMAN
Variants for SULT1A3 Gene
| SNP ID | Clin | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1005284345 | -- | 30,197,850(+) | C/G | upstream_transcript_variant | |
| rs1012475256 | -- | 30,197,522(+) | A/G | upstream_transcript_variant | |
| rs1014971225 | -- | 30,197,882(+) | G/A | upstream_transcript_variant | |
| rs1029479460 | -- | 30,201,046(+) | C/T | coding_sequence_variant, missense_variant | |
| rs1049757961 | -- | 30,197,657(+) | A/C | upstream_transcript_variant |
Gene Damage Index Score:
0.01;
0.17% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SULT1A3 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SULT1A3 Gene
Disorders for SULT1A3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ceroid lipofuscinosis, neuronal, 3 |
|
|
| dengue shock syndrome |
|
|
| hepatic veno-occlusive disease |
|
|
| dengue disease |
|
|
| inhalation anthrax |
|
|
Search SULT1A3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SULT1A3
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for SULT1A3 Gene
Publications for SULT1A3 Gene
- Human liver thermolabile phenol sulfotransferase: cDNA cloning, expression and characterization. (PMID: 8117269) Wood TC … Weinshilboum RM (Biochemical and biophysical research communications 1994) 2 3 4 23 56
- Thermolabile phenol sulfotransferase gene (STM): localization to human chromosome 16p11.2. (PMID: 7829089) Aksoy IA … Weinshilboum RM (Genomics 1994) 2 3 4 23 56
- Crystal structure of human sulfotransferase SULT1A3 in complex with dopamine and 3'-phosphoadenosine 5'-phosphate. (PMID: 16083857) Lu JH … Chang WR (Biochemical and biophysical research communications 2005) 3 4 23 56
- Human catecholamine sulfotransferase (SULT1A3) pharmacogenetics: functional genetic polymorphism. (PMID: 14622112) Thomae BA … Weinshilboum RM (Journal of neurochemistry 2003) 3 4 23 56
- Human thermolabile phenol sulfotransferase gene (STM): molecular cloning and structural characterization. (PMID: 7695637) Aksoy IA … Weinshilboum RM (Biochemical and biophysical research communications 1995) 3 4 23 56
ExternalLinks
Products for SULT1A3 Gene
- Custom Antibody ServicesOriGene Antibodies for SULT1A3
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for SULT1A3
- Origene Custom Protein Services for SULT1A3
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SULT1A3
- Browse OriGene Inhibitory RNA Products For SULT1A3
- OriGene qPCR primer pairs for SULT1A3
- OriGene qPCR primer pairs and template standards for SULT1A3
- OriGene CRISPR knockouts for SULT1A3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SULT1A3
- Sino Biological Human cDNA Clone for SULT1A3
- Sino Biological Recombinant Proteins for SULT1A3
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for SULT1A3
- Browse Sino Biological Assays
- Browse Recombinant Proteins
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SULT1A3
- Novus Biologicals lysates for SULT1A3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SULT1A3
- Abcam proteins for SULT1A3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for SULT1A3 (AFLGC-SULT1A3)
- Santa Cruz Biotechnology (SCBT) Antibodies for SULT1A3
- Search Santa Cruz Biotechnology (SCBT) for SULT1A3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SULT1A3
- Horizon Cell Lines for SULT1A3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SULT1A3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SULT1A3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SULT1A3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SULT1A3
- Biorbyt antibodies for SULT1A3
Sources for SULT1A3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
- (171) LncRNAdb
- (172) Modomics
- (173) PDBe
- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource