Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable en... See more...

Aliases for SULT1A1 Gene

Aliases for SULT1A1 Gene

  • Sulfotransferase Family 1A Member 1 2 3 5
  • Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 2 3
  • Phenol-Sulfating Phenol Sulfotransferase 1 3 4
  • Aryl Sulfotransferase 1 3 4
  • Sulfotransferase 1A1 3 4
  • HAST1/HAST2 3 4
  • EC 2.8.2.1 4 50
  • P-PST 1 3 4
  • Ts-PST 3 4
  • P-PST 2 3
  • ST1A1 3 4
  • ST1A3 3 4
  • STP1 3 4
  • STP 3 4
  • Thermostable Phenol Sulfotransferase1 3
  • Thermostable Phenol Sulfotransferase 4
  • Phenol Sulfotransferase 1 4
  • EC 2.8.2 50
  • SULT1A1 5
  • TSPST1 3
  • PST 3

External Ids for SULT1A1 Gene

Previous HGNC Symbols for SULT1A1 Gene

  • STP
  • STP1

Previous GeneCards Identifiers for SULT1A1 Gene

  • GC16M028946
  • GC16P028674
  • GC16P028431
  • GC16P028469
  • GC16M028524
  • GC16M028616
  • GC16M026642

Summaries for SULT1A1 Gene

Entrez Gene Summary for SULT1A1 Gene

  • Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for SULT1A1 Gene

SULT1A1 (Sulfotransferase Family 1A Member 1) is a Protein Coding gene. Diseases associated with SULT1A1 include Mandibulofacial Dysostosis With Alopecia and Pneumonic Plague. Among its related pathways are Sulfation Biotransformation Reaction and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include sulfotransferase activity and flavonol 3-sulfotransferase activity. An important paralog of this gene is SULT1A4.

UniProtKB/Swiss-Prot Summary for SULT1A1 Gene

  • Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a wide variety of acceptor molecules bearing a hydroxyl or an amine groupe. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Displays broad substrate specificity for small phenolic compounds. Plays an important role in the sulfonation of endogenous molecules such as steroid hormones and 3,3'-diiodothyronin (PubMed:16221673, PubMed:12471039, PubMed:22069470, PubMed:21723874, PubMed:10199779, PubMed:7834621). Mediates the sulfate conjugation of a variety of xenobiotics, including the drugs acetaminophen and minoxidil (By similarity). Mediates also the metabolic activation of carcinogenic N-hydroxyarylamines leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis (PubMed:7834621).

Gene Wiki entry for SULT1A1 Gene

PharmGKB "VIP" Summary for SULT1A1 Gene

No data available for CIViC Summary , Tocris Summary , Rfam classification and piRNA Summary for SULT1A1 Gene

Genomics for SULT1A1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SULT1A1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SULT1A1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SULT1A1

Top Transcription factor binding sites by QIAGEN in the SULT1A1 gene promoter:
  • STAT3

Genomic Locations for SULT1A1 Gene

Latest Assembly
chr16:28,603,944-28,623,625
(GRCh38/hg38)
Size:
19,682 bases
Orientation:
Minus strand

Previous Assembly
chr16:28,616,908-28,634,696
(GRCh37/hg19 by Entrez Gene)
Size:
17,789 bases
Orientation:
Minus strand

chr16:28,616,903-28,634,946
(GRCh37/hg19 by Ensembl)
Size:
18,044 bases
Orientation:
Minus strand

Genomic View for SULT1A1 Gene

Genes around SULT1A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SULT1A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SULT1A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SULT1A1 Gene

Proteins for SULT1A1 Gene

  • Protein details for SULT1A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P50225-ST1A1_HUMAN
    Recommended name:
    Sulfotransferase 1A1
    Protein Accession:
    P50225
    Secondary Accessions:
    • Q2NL71
    • Q86U58
    • Q92818
    • Q9BVU6
    • Q9UGG7

    Protein attributes for SULT1A1 Gene

    Size:
    295 amino acids
    Molecular mass:
    34165 Da
    Quaternary structure:
    • Homodimer.

    Three dimensional structures from OCA and Proteopedia for SULT1A1 Gene

    Alternative splice isoforms for SULT1A1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SULT1A1 Gene

Selected DME Specific Peptides for SULT1A1 Gene

P50225:
  • FTVAQNE
  • ILDMIYQ
  • YVARNAKD
  • LYLFYED
  • PKSGTTW
  • TPAPRLLKTHLPL
  • SPFMRKG
  • PKREIQK
  • YEDMKENPK
  • VSYYHFY
  • LKDTPAPRL
  • PLIKYFAE
  • FQARPDD
  • LLDQKVKV

Post-translational modifications for SULT1A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Domains & Families for SULT1A1 Gene

Gene Families for SULT1A1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins

Protein Domains for SULT1A1 Gene

InterPro:
Blocks:
  • Sulfotransferase

Suggested Antigen Peptide Sequences for SULT1A1 Gene

GenScript: Design optimal peptide antigens:
  • Salt-tolerant protein (A7VJC9_HUMAN)
  • Phenol sulfotransferase (Q9UMT9_HUMAN)
  • Thermostable phenol sulfotransferase (ST1A1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P50225

UniProtKB/Swiss-Prot:

ST1A1_HUMAN :
  • Belongs to the sulfotransferase 1 family.
Family:
  • Belongs to the sulfotransferase 1 family.
genes like me logo Genes that share domains with SULT1A1: view

Function for SULT1A1 Gene

Molecular function for SULT1A1 Gene

UniProtKB/Swiss-Prot Function:
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a wide variety of acceptor molecules bearing a hydroxyl or an amine groupe. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Displays broad substrate specificity for small phenolic compounds. Plays an important role in the sulfonation of endogenous molecules such as steroid hormones and 3,3'-diiodothyronin (PubMed:16221673, PubMed:12471039, PubMed:22069470, PubMed:21723874, PubMed:10199779, PubMed:7834621). Mediates the sulfate conjugation of a variety of xenobiotics, including the drugs acetaminophen and minoxidil (By similarity). Mediates also the metabolic activation of carcinogenic N-hydroxyarylamines leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis (PubMed:7834621).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=3'-phosphoadenylyl sulfate + a phenol = a phenyl sulfate + adenosine 3',5'-bisphosphate + H(+); Xref=Rhea:RHEA:12164, ChEBI:CHEBI:15378, ChEBI:CHEBI:33853, ChEBI:CHEBI:58339, ChEBI:CHEBI:58343, ChEBI:CHEBI:140317; EC=2.8.2.1; Evidence={ECO:0000269|PubMed:10199779, ECO:0000269|PubMed:12471039, ECO:0000269|PubMed:16221673, ECO:0000269|PubMed:21723874, ECO:0000269|PubMed:22069470, ECO:0000269|PubMed:7834621};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=17beta-estradiol + 3'-phosphoadenylyl sulfate = 17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+); Xref=Rhea:RHEA:52372, ChEBI:CHEBI:15378, ChEBI:CHEBI:16469, ChEBI:CHEBI:58339, ChEBI:CHEBI:58343, ChEBI:CHEBI:136582; Evidence={ECO:0000269|PubMed:16221673};.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=0.12 uM for 3,3'-diiodothyronin {ECO:0000269|PubMed:10199779}; Vmax=465 umol/min/mg enzyme with 3,3'-diiodothyronin as substrate {ECO:0000269|PubMed:10199779};
GENATLAS Biochemistry:
aryl (phenol) sulfotransferase 1,phenol preferring,cytosolic,catalyzing the sulphonation of dopamine and p-nitrophenol

Enzyme Numbers (IUBMB) for SULT1A1 Gene

Phenotypes From GWAS Catalog for SULT1A1 Gene

Gene Ontology (GO) - Molecular Function for SULT1A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004062 aryl sulfotransferase activity IEA,IDA 12471039
GO:0005515 protein binding IPI 25416956
GO:0008146 sulfotransferase activity IEA,IDA 19548878
GO:0016740 transferase activity IEA --
GO:0047894 flavonol 3-sulfotransferase activity IDA 20056724
genes like me logo Genes that share ontologies with SULT1A1: view
genes like me logo Genes that share phenotypes with SULT1A1: view

miRNA for SULT1A1 Gene

miRTarBase miRNAs that target SULT1A1

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SULT1A1

Clone products for research

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SULT1A1 Gene

Localization for SULT1A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SULT1A1 Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SULT1A1 gene
Compartment Confidence
cytosol 5
plasma membrane 2
extracellular 2
mitochondrion 2
nucleus 2
cytoskeleton 1
peroxisome 1
endoplasmic reticulum 1
lysosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for SULT1A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA 21873635
GO:0005829 cytosol TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SULT1A1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for SULT1A1 Gene

Pathways & Interactions for SULT1A1 Gene

genes like me logo Genes that share pathways with SULT1A1: view

Pathways by source for SULT1A1 Gene

Interacting Proteins for SULT1A1 Gene

Gene Ontology (GO) - Biological Process for SULT1A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006068 ethanol catabolic process IDA 23207770
GO:0006584 catecholamine metabolic process IEA --
GO:0006629 lipid metabolic process IEA --
GO:0006805 xenobiotic metabolic process IDA 12471039
GO:0008202 steroid metabolic process IEA --
genes like me logo Genes that share ontologies with SULT1A1: view

No data available for SIGNOR curated interactions for SULT1A1 Gene

Drugs & Compounds for SULT1A1 Gene

(48) Drugs for SULT1A1 Gene - From: DrugBank, PharmGKB, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Acetaminophen Approved Pharma Enzyme, substrate 1412
Apomorphine Approved, Investigational Pharma Enzyme, substrate 49
Tamoxifen Approved Pharma Enzyme, substrate TGF-β modulatory and PKC inhibitory effects, ER antagonist, Anti-Estrogens 469
Phenol Approved, Experimental Pharma 73
Methyldopa Approved Pharma Enzyme, substrate 19

(23) Additional Compounds for SULT1A1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with SULT1A1: view

Transcripts for SULT1A1 Gene

mRNA/cDNA for SULT1A1 Gene

5 REFSEQ mRNAs :
21 NCBI additional mRNA sequence :
10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SULT1A1

Clone products for research

Alternative Splicing Database (ASD) splice patterns (SP) for SULT1A1 Gene

No ASD Table

Relevant External Links for SULT1A1 Gene

GeneLoc Exon Structure for
SULT1A1

Expression for SULT1A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SULT1A1 Gene

mRNA differential expression in normal tissues according to GTEx for SULT1A1 Gene

This gene is overexpressed in Liver (x6.7) and Whole Blood (x5.0).

Protein differential expression in normal tissues from HIPED for SULT1A1 Gene

This gene is overexpressed in Gallbladder (34.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SULT1A1 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SULT1A1

SOURCE GeneReport for Unigene cluster for SULT1A1 Gene:

Hs.567342

mRNA Expression by UniProt/SwissProt for SULT1A1 Gene:

P50225-ST1A1_HUMAN
Tissue specificity: Liver, lung, adrenal, brain, platelets and skin.

Evidence on tissue expression from TISSUES for SULT1A1 Gene

  • Liver(4.7)
  • Intestine(4.6)
  • Blood(4.5)
  • Nervous system(4.5)
  • Thyroid gland(2.6)
  • Kidney(2.6)
  • Adrenal gland(2.6)
  • Lung(2.5)
  • Stomach(2.2)
  • Heart(2.1)
genes like me logo Genes that share expression patterns with SULT1A1: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for SULT1A1 Gene

Orthologs for SULT1A1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SULT1A1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SULT1A1 29 30
  • 98.98 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia SULT1A1 30
  • 86 (a)
OneToMany
Cow
(Bos Taurus)
Mammalia SULT1A1 30
  • 84 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 30
  • 75 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Sult1a1 30
  • 75 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 30
  • 48 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 30
  • 60 (a)
ManyToMany
-- 30
  • 59 (a)
ManyToMany
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia sult1a1 29
  • 62.7 (n)
African clawed frog
(Xenopus laevis)
Amphibia MGC64389 29
Zebrafish
(Danio rerio)
Actinopterygii sult1st3 29
  • 55.98 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta CG5428 31
  • 32 (a)
CG16733 31
  • 27 (a)
Species where no ortholog for SULT1A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for SULT1A1 Gene

ENSEMBL:
Gene Tree for SULT1A1 (if available)
TreeFam:
Gene Tree for SULT1A1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SULT1A1: view image
Alliance of Genome Resources:
Additional Orthologs for SULT1A1

Paralogs for SULT1A1 Gene

(15) SIMAP similar genes for SULT1A1 Gene using alignment to 5 proteins:

  • ST1A1_HUMAN
  • H3BMH9_HUMAN
  • H3BQX5_HUMAN
  • H3BRY5_HUMAN
  • H3BT96_HUMAN

Pseudogenes.org Pseudogenes for SULT1A1 Gene

genes like me logo Genes that share paralogs with SULT1A1: view

Variants for SULT1A1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for SULT1A1 Gene

ST1A1_HUMAN-P50225
There are several alleles. The sequence shown is that of allele SULT1A1*3.

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SULT1A1 Gene

SNP ID Clinical significance and condition Chr 16 pos Variation AA Info Type
rs141343888 Uncertain Significance: not provided 28,608,538(-) G/A
NM_001055.3(SULT1A1):c.214C>T (p.Arg72Ter)
NONSENSE,INTRON
rs1042011 -- p.Glu151Gln
rs1042014 -- p.Glu151Asp
rs1042028 -- p.Arg213His
rs1801030 -- p.Val223Met

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SULT1A1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SULT1A1 Gene

Variant ID Type Subtype PubMed ID
dgv12n14 CNV loss 18776910
dgv2830n100 CNV gain 25217958
dgv4971n54 CNV loss 21841781
dgv4972n54 CNV loss 21841781
dgv4973n54 CNV loss 21841781
dgv4974n54 CNV gain+loss 21841781
dgv4975n54 CNV gain+loss 21841781
dgv4976n54 CNV loss 21841781
dgv4977n54 CNV gain+loss 21841781
dgv4978n54 CNV gain 21841781
dgv4979n54 CNV gain+loss 21841781
dgv4980n54 CNV loss 21841781
dgv4981n54 CNV loss 21841781
dgv501e214 CNV gain 21293372
esv24682 CNV gain+loss 19812545
esv2667967 CNV deletion 23128226
esv2714170 CNV deletion 23290073
esv2758640 CNV gain+loss 17122850
esv33847 CNV gain 17666407
esv3553298 CNV deletion 23714750
esv3638338 CNV loss 21293372
esv3892821 CNV loss 25118596
esv3892822 CNV loss 25118596
esv3892823 CNV gain 25118596
esv993722 CNV gain 20482838
esv998803 CNV gain 20482838
nsv1059555 CNV gain 25217958
nsv1064483 CNV loss 25217958
nsv1066415 CNV gain 25217958
nsv1115500 CNV duplication 24896259
nsv1123028 CNV deletion 24896259
nsv1127483 CNV deletion 24896259
nsv1153455 CNV duplication 26484159
nsv1775 CNV insertion 18451855
nsv433301 CNV loss 18776910
nsv433302 CNV loss 18776910
nsv435671 CNV deletion 17901297
nsv509608 CNV insertion 20534489
nsv571749 CNV gain 21841781
nsv571755 CNV gain 21841781
nsv571756 CNV gain 21841781
nsv571766 CNV loss 21841781
nsv571767 CNV gain+loss 21841781
nsv571768 CNV loss 21841781
nsv571776 CNV loss 21841781
nsv571777 CNV gain 21841781
nsv571778 CNV loss 21841781
nsv819128 CNV loss 19587683
nsv820569 CNV duplication 20802225
nsv827606 CNV loss 20364138
nsv827607 CNV gain+loss 20364138
nsv827608 CNV gain+loss 20364138
nsv833182 CNV gain 17160897
nsv9416 CNV gain+loss 18304495
nsv977945 CNV duplication 23825009
nsv984300 CNV duplication 23825009

Variation tolerance for SULT1A1 Gene

Residual Variation Intolerance Score: 82.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.64; 31.40% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SULT1A1 Gene

Human Gene Mutation Database (HGMD)
SULT1A1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SULT1A1
Leiden Open Variation Database (LOVD)
SULT1A1

SNP Genotyping and Copy Number Assays for research

Disorders for SULT1A1 Gene

MalaCards: The human disease database

(8) MalaCards diseases for SULT1A1 Gene - From: COP and GCD

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SULT1A1

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with SULT1A1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SULT1A1 Gene

Publications for SULT1A1 Gene

  1. Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2. (PMID: 10762004) Engelke CE … Glatt H (Pharmacogenetics 2000) 3 4 22 40
  2. Genomic organization and DNA sequences of two human phenol sulfotransferase genes (STP1 and STP2) on the short arm of chromosome 16. (PMID: 8912648) Dooley TP … Huang Z (Biochemical and biophysical research communications 1996) 2 3 4 22
  3. Mapping of the phenol sulfotransferase gene (STP) to human chromosome 16p12.1-p11.2 and to mouse chromosome 7. (PMID: 8288252) Dooley TP … Siciliano MJ (Genomics 1993) 2 3 4 22
  4. Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States. (PMID: 20142249) Yong M … Lampe JW (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 22 40
  5. Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women. (PMID: 19424794) MARIE-GENICA Consortium on Genetic Susceptibility for Menopausal Hormone Therapy Related Breast Cancer Risk (Breast cancer research and treatment 2010) 3 22 40

Products for SULT1A1 Gene

Sources for SULT1A1 Gene