Aliases for SUGCT Gene
External Ids for SUGCT Gene
Previous HGNC Symbols for SUGCT Gene
Previous GeneCards Identifiers for SUGCT Gene
This gene encodes a protein that is similar to members of the CaiB/baiF CoA-transferase protein family. Mutations in this gene are associated with glutaric aciduria type III. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
GeneCards Summary for SUGCT Gene
SUGCT (Succinyl-CoA:Glutarate-CoA Transferase) is a Protein Coding gene. Diseases associated with SUGCT include Glutaric Aciduria Iii and Cataract 4, Multiple Types. Gene Ontology (GO) annotations related to this gene include succinate-hydroxymethylglutarate CoA-transferase activity. An important paralog of this gene is AMACR.
UniProtKB/Swiss-Prot Summary for SUGCT Gene
Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate.