Aliases for STYK1 Gene
External Ids for STYK1 Gene
Previous GeneCards Identifiers for STYK1 Gene
Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008]
GeneCards Summary for STYK1 Gene
STYK1 (Serine/Threonine/Tyrosine Kinase 1) is a Protein Coding gene. Diseases associated with STYK1 include Prostate Small Cell Carcinoma and Cervix Carcinoma. Among its related pathways are Focal Adhesion. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is YES1.
UniProtKB/Swiss-Prot Summary for STYK1 Gene
Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity).