Aliases for STXBP3 Gene
Aliases for STXBP3 Gene
External Ids for STXBP3 Gene
- HGNC: 11446
- Entrez Gene: 6814
- Ensembl: ENSG00000116266
- OMIM: 608339
- UniProtKB: O00186
Previous GeneCards Identifiers for STXBP3 Gene
- GC01M109954
- GC01P108266
- GC01P108387
- GC01P108635
- GC01P109001
- GC01P109094
- GC01P109289
- GC01P107182
Summaries for STXBP3 Gene
GeneCards Summary for STXBP3 Gene
STXBP3 (Syntaxin Binding Protein 3) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Angiopoietin Like Protein 8 Regulatory Pathway. Gene Ontology (GO) annotations related to this gene include syntaxin binding and syntaxin-1 binding. An important paralog of this gene is STXBP1.
UniProtKB/Swiss-Prot for STXBP3 Gene
-
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Additional gene information for STXBP3 Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STXBP3 Gene
Genomics for STXBP3 Gene
GeneHancer (GH) Regulatory Elements for STXBP3 Gene
Promoters and enhancers for STXBP3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around STXBP3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for STXBP3 Gene
Genomic Locations for STXBP3 Gene
- chr1:108,746,663-108,809,526
- (GRCh38/hg38)
- Size:
- 62,864 bases
- Orientation:
- Plus strand
- chr1:109,289,285-109,352,148
- (GRCh37/hg19)
Genomic View for STXBP3 Gene
Genes around STXBP3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p13.3 by Ensembl
- 1p13.3 by Entrez Gene
- 1p13.3 by HGNC
STXBP3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for STXBP3 Gene
Proteins for STXBP3 Gene
-
Protein details for STXBP3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O00186-STXB3_HUMAN
- Recommended name:
- Syntaxin-binding protein 3
- Protein Accession:
- O00186
- A8K269
- A8K5K7
- Q53FW1
- Q86YJ3
- Q9UPD7
Protein attributes for STXBP3 Gene
- Size:
- 592 amino acids
- Molecular mass:
- 67764 Da
- Quaternary structure:
-
- Interacts with DOC2B; the interaction is direct, occurs at the cell membrane, excludes interaction with STX4 and regulates glucose-stimulated insulin secretion (By similarity). Interacts with STX4.
Protein Expression for STXBP3 Gene
Post-translational modifications for STXBP3 Gene
- Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4.
Other Protein References for STXBP3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for STXBP3 (Syntaxin-BP3)
-
Custom Antibody ServicesOriGene Antibodies for STXBP3
- Novus Biologicals Antibodies for STXBP3
-
Abcam antibodies for STXBP3
- Invitrogen Antibodies for STXBP3
- antibodies-online: Search results for 57 available STXBP3 Antibodies ranked by validation data
- Compare Top STXBP3 Antibodies
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Recommended
- 3 IHC (p) Antibodies (anti-rat)
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- 3 IHC (p) Antibodies (anti-mouse)
- 8 WB Antibodies (anti-mouse)
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- 3 IHC (p) Antibodies (anti-rat)
- 6 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 3 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 35 WB Antibodies (anti-human)
- 3 IHC (p) Antibodies (anti-mouse)
- 8 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- Search GeneTex for Antibodies for STXBP3
-
Santa Cruz Biotechnology (SCBT) Antibodies for STXBP3
Protein Products
-
OriGene Purified Proteins for STXBP3
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- Search GeneTex for Proteins for STXBP3
-
Abcam proteins for STXBP3
Assay Products
No data available for DME Specific Peptides for STXBP3 Gene
Domains & Families for STXBP3 Gene
Gene Families for STXBP3 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for STXBP3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for STXBP3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O00186- Family:
-
- Belongs to the STXBP/unc-18/SEC1 family.
Function for STXBP3 Gene
Molecular function for STXBP3 Gene
- UniProtKB/Swiss-Prot Function:
- Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 12773094 |
| GO:0017075 | syntaxin-1 binding | IEA | -- |
| GO:0019905 | syntaxin binding | IEA,IPI | 12773094 |
Phenotypes for STXBP3 Gene
- MGI mutant phenotypes for STXBP3:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for STXBP3:
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for STXBP3 gene
-
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CRISPR Products
-
OriGene CRISPR knockouts for STXBP3
- genomics-online: gRNA clones - Search results for available STXBP3 gene related products
- Applied Biological Materials CRISPR for STXBP3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for STXBP3
- GenScript: Design CRISPR guide RNA sequences for STXBP3
miRNA for STXBP3 Gene
- miRTarBase miRNAs that target STXBP3
miRNA Products
- Search ViGene Biosciences for STXBP3
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for STXBP3
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-
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available STXBP3 gene related products
- orf clones - Search results for available STXBP3 gene related products
- Applied Biological Materials Clones for STXBP3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for STXBP3
-
ViGene Biosciences adenoviral particle packaged cDNA for STXBP3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for STXBP3 gene
-
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for STXBP3 Gene
Localization for STXBP3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for STXBP3 Gene
- Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| cytosol | 5 |
| nucleus | 3 |
| mitochondrion | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | IDA,IEA | 18588921 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016323 | basolateral plasma membrane | IEA | -- |
Pathways & Interactions for STXBP3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Response to elevated platelet cytosolic Ca2+ |
.44
|
|
| 2 | Vesicle-mediated transport | ||
| 3 | Translocation of GLUT4 to the plasma membrane | ||
| 4 | Angiopoietin Like Protein 8 Regulatory Pathway | ||
Pathways by source for STXBP3 Gene
1 BioSystems pathway for STXBP3 Gene
7 Reactome pathways for STXBP3 Gene
Interacting Proteins for STXBP3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0006887 | exocytosis | IEA | -- |
| GO:0006904 | vesicle docking involved in exocytosis | IEA | -- |
| GO:0007420 | brain development | IEA | -- |
| GO:0015031 | protein transport | IEA | -- |
No data available for SIGNOR curated interactions for STXBP3 Gene
Transcripts for STXBP3 Gene
mRNA/cDNA for STXBP3 Gene
- (1) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (188) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for STXBP3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for STXBP3
- genomics-online: gRNA clones - Search results for available STXBP3 gene related products
- Applied Biological Materials CRISPR for STXBP3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for STXBP3
- GenScript: Design CRISPR guide RNA sequences for STXBP3
miRNA Products
- Search ViGene Biosciences for STXBP3
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for STXBP3
- Browse OriGene Inhibitory RNA Products For STXBP3
- genomics-online: shRNA clones - Search results for available STXBP3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for STXBP3 gene
Clone Products
- Sino Biological Human cDNA Clone for STXBP3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for STXBP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for STXBP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available STXBP3 gene related products
- orf clones - Search results for available STXBP3 gene related products
- Applied Biological Materials Clones for STXBP3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||
| SP4: |
Expression for STXBP3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
- Hematopoietic Bone Marrow
This gene is overexpressed in Peripheral blood mononuclear cells (18.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for STXBP3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of STXBP3 Gene:
STXBP3SOURCE GeneReport for Unigene cluster for STXBP3 Gene:
Hs.530436mRNA Expression by UniProt/SwissProt for STXBP3 Gene:
O00186-STXB3_HUMAN
Tissue specificity:
Megakaryocytes and platelets.
Evidence on tissue expression from TISSUES for STXBP3 Gene
- Nervous system(4.8)
- Lung(4.3)
- Liver(4.2)
- Pancreas(2.2)
- Muscle(2.1)
Primer Products
-
OriGene qPCR primer pairs for STXBP3
-
OriGene qPCR primer pairs and template standards for STXBP3
- genomics-online: primer clones - Search results for available STXBP3 gene related products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for STXBP3 Gene
Orthologs for STXBP3 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | STXBP3 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | STXBP3 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | STXBP3 33 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | STXBP3 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Stxbp3a 33 34 |
|
||
| Stxbp3b 34 |
|
OneToMany | |||
| Stxbp3 16 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | Stxbp3 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | STXBP3 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | STXBP3 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | STXBP3 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | stxbp3 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.16785 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | stxbp3 33 34 |
|
||
| wufb71h06 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Rop 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | unc-18 34 |
|
OneToMany | |
| T07A9.10 35 |
|
|
|||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SEC1 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for STXBP3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for STXBP3 Gene
Variants for STXBP3 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000060587 | -- | 108,774,866(+) | T/C | intron_variant | |
| rs1000083808 | -- | 108,790,525(+) | A/G | intron_variant | |
| rs1000195692 | -- | 108,746,622(+) | T/C | upstream_transcript_variant | |
| rs1000315146 | -- | 108,750,813(+) | C/T | intron_variant | |
| rs1000399297 | -- | 108,777,104(+) | G/A | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv947442 | CNV | duplication | 23825009 |
| nsv823908 | CNV | loss | 20364138 |
| nsv2287 | CNV | deletion | 18451855 |
| nsv1153780 | CNV | deletion | 26484159 |
| nsv1140419 | CNV | tandem duplication | 24896259 |
| nsv1078622 | CNV | deletion | 25765185 |
| nsv1078057 | CNV | deletion | 25765185 |
| nsv1013192 | CNV | gain | 25217958 |
| esv3587137 | CNV | loss | 21293372 |
| esv29430 | CNV | loss | 19812545 |
| esv1070190 | CNV | deletion | 17803354 |
| dgv487n54 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
26.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.01;
49.98% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for STXBP3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for STXBP3 Gene
Disorders for STXBP3 Gene
Additional Disease Information for STXBP3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for STXBP3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for STXBP3 Gene
Publications for STXBP3 Gene
- Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion. (PMID: 10194441) Reed GL … Fitzgerald ML (Blood 1999) 2 3 4 22 58
- Identification of type 2 diabetes-associated combination of SNPs using support vector machine. (PMID: 20416077) Ban HJ … Park KJ (BMC genetics 2010) 3 44 58
- Involvement of Munc18 isoforms in the regulation of granule exocytosis in neutrophils. (PMID: 18588921) Brochetta C … Blank U (Biochimica et biophysica acta 2008) 3 22 58
- Identification of 80K-H as a protein involved in GLUT4 vesicle trafficking. (PMID: 15707389) Hodgkinson CP … Sale GJ (The Biochemical journal 2005) 3 22 58
- Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression. (PMID: 15576373) Fu J … Malik AB (The Journal of biological chemistry 2005) 3 22 58
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for STXBP3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 57 available STXBP3 Antibodies ranked by validation data
- Compare Top STXBP3 Antibodies
- Recommended
- 12 IF (p) Antibodies (anti-mouse)
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- antibodies-online: Search results for available STXBP3 related products ranked by validation data
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- Search GeneTex for Proteins for STXBP3
- ViGene Biosciences adenoviral particle packaged cDNA for STXBP3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for STXBP3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for STXBP3 gene
- Search ViGene Biosciences for STXBP3
- Santa Cruz Biotechnology (SCBT) Antibodies for STXBP3
- Search Santa Cruz Biotechnology (SCBT) for STXBP3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for STXBP3
- Horizon Cell Lines for STXBP3
- genomics-online: cdna clones - Search results for available STXBP3 gene related products
- orf clones - Search results for available STXBP3 gene related products
- genomics-online: gRNA clones - Search results for available STXBP3 gene related products
- genomics-online: primer clones - Search results for available STXBP3 gene related products
- genomics-online: shRNA clones - Search results for available STXBP3 gene related products
Sources for STXBP3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew