This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcri... See more...

Aliases for STXBP2 Gene

Aliases for STXBP2 Gene

  • Syntaxin Binding Protein 2 2 3 5
  • UNC18B 2 3 4
  • Syntaxin-Binding Protein 2 3 4
  • Protein Unc-18 Homolog B 3 4
  • Hunc18b 2 3
  • Unc-18B 3 4
  • Protein Unc-18 Homolog 2 4
  • MUNC18-2 3
  • UNC18-2 3
  • Pp10122 3
  • Unc18-2 4
  • STXBP2 5
  • FHL5 3

External Ids for STXBP2 Gene

Previous GeneCards Identifiers for STXBP2 Gene

  • GC19P007660
  • GC19P007806
  • GC19P007596
  • GC19P007608
  • GC19P007701
  • GC19P007371

Summaries for STXBP2 Gene

Entrez Gene Summary for STXBP2 Gene

  • This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013]

GeneCards Summary for STXBP2 Gene

STXBP2 (Syntaxin Binding Protein 2) is a Protein Coding gene. Diseases associated with STXBP2 include Hemophagocytic Lymphohistiocytosis, Familial, 5 and Hemophagocytic Lymphohistiocytosis, Familial, 1. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Angiopoietin Like Protein 8 Regulatory Pathway. Gene Ontology (GO) annotations related to this gene include syntaxin-1 binding and syntaxin-3 binding. An important paralog of this gene is STXBP1.

UniProtKB/Swiss-Prot Summary for STXBP2 Gene

  • Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.

Gene Wiki entry for STXBP2 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for STXBP2 Gene

Genomics for STXBP2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for STXBP2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J007636 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 625 +0.5 484 2.3 LEF1 POLR2A JUND LARP7 MTA2 ZIC2 RBFOX2 PKNOX1 PATZ1 REST STXBP2 ENSG00000268204 PCP2 PET100 ENSG00000268400 MN297555 L13712-012 RETN
GH19J007635 Promoter 0.4 Ensembl 600.7 -1.7 -1680 0.8 ZNF366 ENSG00000268204 PCP2 STXBP2 XAB2 ENSG00000268400 NONHSAG024646.2 L13712-012
GH19J007638 Enhancer 0.3 ENCODE 623.5 +1.9 1869 0.2 CBFA2T2 STXBP2 ENSG00000268204 PCP2 MN297555 ENSG00000268400 L13712-012 RETN
GH19J007700 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 17.5 +67.6 67607 7 SP1 IKZF1 KDM1A POLR2A BACH1 LARP7 STAT3 ZNF143 RELA ZIC2 FCER2 STXBP2 ELAVL1 HNRNPM XAB2 PEX11G MAP2K7 CD209 CLEC4G RPL21P129
GH19J007678 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas 14.4 +43.8 43814 3.6 CEBPG HNRNPL CREB1 GATAD2A CTCF ZNF692 BACH1 TARDBP FOXA1 LARP7 MCEMP1 TRAPPC5 HNRNPM ELAVL1 XAB2 ZNF557 MAP2K7 STXBP2 ZNF414 PEX11G
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around STXBP2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for STXBP2

Top Transcription factor binding sites by QIAGEN in the STXBP2 gene promoter:
  • GCNF
  • GCNF-1
  • GCNF-2
  • GR
  • GR-alpha
  • Lmo2
  • Nkx2-5
  • SEF-1 (1)
  • Sp1
  • STAT3

Genomic Locations for STXBP2 Gene

Genomic Locations for STXBP2 Gene
chr19:7,636,881-7,647,873
(GRCh38/hg38)
Size:
10,993 bases
Orientation:
Plus strand
chr19:7,701,767-7,712,759
(GRCh37/hg19)
Size:
10,993 bases
Orientation:
Plus strand

Genomic View for STXBP2 Gene

Genes around STXBP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
STXBP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for STXBP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STXBP2 Gene

Proteins for STXBP2 Gene

  • Protein details for STXBP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15833-STXB2_HUMAN
    Recommended name:
    Syntaxin-binding protein 2
    Protein Accession:
    Q15833
    Secondary Accessions:
    • B4E175
    • E7EQD5
    • Q9BU65

    Protein attributes for STXBP2 Gene

    Size:
    593 amino acids
    Molecular mass:
    66453 Da
    Quaternary structure:
    • Interacts with STX1A, STX2 and STX3 (By similarity). Interacts with STX11.

    Three dimensional structures from OCA and Proteopedia for STXBP2 Gene

    Alternative splice isoforms for STXBP2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for STXBP2 Gene

Post-translational modifications for STXBP2 Gene

  • Ubiquitination at Lys13, Lys63, Lys89, Lys208, Lys213, Lys225, Lys320, Lys324, Lys480, and Lys560
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for STXBP2 Gene

Domains & Families for STXBP2 Gene

Gene Families for STXBP2 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for STXBP2 Gene

InterPro:
Blocks:
  • Sec1-like protein
ProtoNet:

Suggested Antigen Peptide Sequences for STXBP2 Gene

GenScript: Design optimal peptide antigens:
  • Protein unc-18 homolog B (STXB2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q15833

UniProtKB/Swiss-Prot:

STXB2_HUMAN :
  • Belongs to the STXBP/unc-18/SEC1 family.
Family:
  • Belongs to the STXBP/unc-18/SEC1 family.
genes like me logo Genes that share domains with STXBP2: view

Function for STXBP2 Gene

Molecular function for STXBP2 Gene

UniProtKB/Swiss-Prot Function:
Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.
GENATLAS Biochemistry:
syntaxin binding protein 2,expressed predominantly in placenta,lung,liver,kidney,pancreas,soluble N ethylmaleimide-sensitive factor-attachment protein receptor,SNARE protein

Phenotypes From GWAS Catalog for STXBP2 Gene

Gene Ontology (GO) - Molecular Function for STXBP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 19804848
GO:0017075 syntaxin-1 binding IEA,IBA 21873635
GO:0019905 syntaxin binding IBA 21873635
GO:0030348 syntaxin-3 binding IPI 18588921
genes like me logo Genes that share ontologies with STXBP2: view
genes like me logo Genes that share phenotypes with STXBP2: view

Human Phenotype Ontology for STXBP2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for STXBP2 Gene

MGI Knock Outs for STXBP2:

Animal Model Products

CRISPR Products

miRNA for STXBP2 Gene

miRTarBase miRNAs that target STXBP2

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for STXBP2

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for STXBP2 Gene

Localization for STXBP2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for STXBP2 gene
Compartment Confidence
plasma membrane 5
cytosol 5
lysosome 5
extracellular 4
nucleus 2
endosome 2
cytoskeleton 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for STXBP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005829 cytosol IDA,TAS --
GO:0005886 plasma membrane IDA 18588921
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with STXBP2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for STXBP2 Gene

Pathways & Interactions for STXBP2 Gene

genes like me logo Genes that share pathways with STXBP2: view

Pathways by source for STXBP2 Gene

SIGNOR curated interactions for STXBP2 Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for STXBP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001909 leukocyte mediated cytotoxicity IMP 19884660
GO:0002576 platelet degranulation TAS --
GO:0006886 intracellular protein transport IBA 21873635
GO:0006887 exocytosis IEA --
GO:0006904 vesicle docking involved in exocytosis IEA,IBA 21873635
genes like me logo Genes that share ontologies with STXBP2: view

Drugs & Compounds for STXBP2 Gene

(1) Drugs for STXBP2 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
emapalumab Approved, Investigational Pharma 0
genes like me logo Genes that share compounds with STXBP2: view

Transcripts for STXBP2 Gene

mRNA/cDNA for STXBP2 Gene

3 REFSEQ mRNAs :
15 NCBI additional mRNA sequence :
22 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for STXBP2

Alternative Splicing Database (ASD) splice patterns (SP) for STXBP2 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b · 15c · 15d · 15e ^
SP1: - - - - -
SP2: - - - - - -
SP3: - - -
SP4: - -
SP5: - - -
SP6: - - - - - -
SP7: - - - - -
SP8:
SP9:
SP10:
SP11:

ExUns: 16a · 16b ^ 17a · 17b ^ 18 ^ 19 ^ 20
SP1: - -
SP2: - -
SP3:
SP4:
SP5: - - -
SP6:
SP7:
SP8: -
SP9:
SP10:
SP11:

Relevant External Links for STXBP2 Gene

GeneLoc Exon Structure for
STXBP2

Expression for STXBP2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for STXBP2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for STXBP2 Gene

This gene is overexpressed in Whole Blood (x24.9).

Protein differential expression in normal tissues from HIPED for STXBP2 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (34.6) and Platelet (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for STXBP2 Gene



Protein tissue co-expression partners for STXBP2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for STXBP2

SOURCE GeneReport for Unigene cluster for STXBP2 Gene:

Hs.515104

mRNA Expression by UniProt/SwissProt for STXBP2 Gene:

Q15833-STXB2_HUMAN
Tissue specificity: Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.

Evidence on tissue expression from TISSUES for STXBP2 Gene

  • Kidney(4.5)
  • Lung(4.4)
  • Blood(3.5)
  • Bone marrow(3.2)
  • Nervous system(2.8)
  • Spleen(2.7)
  • Lymph node(2.6)
  • Intestine(2.6)
  • Skin(2.4)
  • Liver(2.4)
  • Pancreas(2.2)
  • Adrenal gland(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for STXBP2 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • immune
  • integumentary
  • lymphatic
  • nervous
  • respiratory
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • cerebrospinal fluid
  • ear
  • eye
  • head
  • meninges
  • mouth
  • neck
  • skull
Thorax:
  • heart
  • lung
Abdomen:
  • biliary tract
  • duodenum
  • intestine
  • liver
  • pancreas
  • small intestine
  • spleen
Limb:
  • lower limb
  • upper limb
General:
  • blood
  • blood vessel
  • bone marrow
  • coagulation system
  • lymph node
  • red blood cell
  • skin
  • spinal cord
  • white blood cell
genes like me logo Genes that share expression patterns with STXBP2: view

Orthologs for STXBP2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for STXBP2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia STXBP2 30 31
  • 97.25 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia STXBP2 30 31
  • 88.93 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia STXBP2 30 31
  • 88.65 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Stxbp2 30 17 31
  • 87.8 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Stxbp2 30
  • 87.3 (n)
Oppossum
(Monodelphis domestica)
Mammalia STXBP2 31
  • 72 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia STXBP2 31
  • 66 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia STXBP2 31
  • 71 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia stxbp2 30
  • 67.92 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.30298 30
Zebrafish
(Danio rerio)
Actinopterygii stxbp2 30 31
  • 68.81 (n)
OneToOne
Dr.7775 30
Fruit Fly
(Drosophila melanogaster)
Insecta Rop 31 32
  • 55 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea unc-18 31 32
  • 46 (a)
OneToMany
T07A9.10 32
  • 31 (a)
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SEC1 30 31 33
  • 42.63 (n)
OneToMany
A. gosspyii yeast
(Eremothecium gossypii)
Saccharomycetes AGOS_AGL162C 30
  • 41.24 (n)
K. Lactis Yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0D17028g 30
  • 39.39 (n)
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 53 (a)
OneToMany
Bread mold
(Neurospora crassa)
Ascomycetes NCU08312 30
  • 47.18 (n)
Fission Yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes sec1 30
  • 41.24 (n)
Species where no ortholog for STXBP2 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for STXBP2 Gene

ENSEMBL:
Gene Tree for STXBP2 (if available)
TreeFam:
Gene Tree for STXBP2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for STXBP2: view image

Paralogs for STXBP2 Gene

(4) SIMAP similar genes for STXBP2 Gene using alignment to 9 proteins:

  • STXB2_HUMAN
  • E7EQD5_HUMAN
  • M0QZ54_HUMAN
  • M0R0D4_HUMAN
  • M0R0M7_HUMAN
  • M0R118_HUMAN
  • M0R1A1_HUMAN
  • M0R376_HUMAN
  • R4GMY7_HUMAN
genes like me logo Genes that share paralogs with STXBP2: view

Variants for STXBP2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for STXBP2 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
639204 Uncertain Significance: Hemophagocytic lymphohistiocytosis, familial, 5 7,642,034(+) G/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
639894 Uncertain Significance: Hemophagocytic lymphohistiocytosis, familial, 5 7,644,747(+) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
640802 Uncertain Significance: Hemophagocytic lymphohistiocytosis, familial, 5 7,639,755(+) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
641714 Uncertain Significance: Hemophagocytic lymphohistiocytosis, familial, 5 7,637,154(+) C/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
642155 Uncertain Significance: Hemophagocytic lymphohistiocytosis, familial, 5 7,647,223(+) C/G MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for STXBP2 Gene

Structural Variations from Database of Genomic Variants (DGV) for STXBP2 Gene

Variant ID Type Subtype PubMed ID
esv2718098 CNV deletion 23290073
esv2751809 CNV gain 17911159
esv3441753 CNV duplication 20981092
nsv1060887 CNV gain 25217958
nsv1117210 CNV tandem duplication 24896259
nsv578511 CNV gain 21841781
nsv833731 CNV loss 17160897
nsv953958 CNV deletion 24416366

Variation tolerance for STXBP2 Gene

Residual Variation Intolerance Score: 35.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.70; 57.36% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for STXBP2 Gene

Human Gene Mutation Database (HGMD)
STXBP2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
STXBP2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for STXBP2 Gene

Disorders for STXBP2 Gene

MalaCards: The human disease database

(23) MalaCards diseases for STXBP2 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

STXB2_HUMAN
  • Familial hemophagocytic lymphohistiocytosis 5 (FHL5) [MIM:613101]: A rare disorder characterized by immune dysregulation with hypercytokinemia, defective function of natural killer cell, and massive infiltration of several organs by activated lymphocytes and macrophages. The clinical features of the disease include fever, hepatosplenomegaly, cytopenia, and less frequently neurological abnormalities ranging from irritability and hypotonia to seizures, cranial nerve deficits and ataxia. {ECO:0000269 PubMed:19804848, ECO:0000269 PubMed:19884660}. Note=The disease is caused by mutations affecting the gene represented in this entry.
genes like me logo Genes that share disorders with STXBP2: view

No data available for Genatlas for STXBP2 Gene

Publications for STXBP2 Gene

  1. Molecular characterization of a nonneuronal human UNC18 homolog. (PMID: 8921365) Ziegler SF … Mulligan JT (Genomics 1996) 2 3 4 23
  2. Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells. (PMID: 19884660) Côte M … de Saint Basile G (The Journal of clinical investigation 2009) 3 4 23
  3. Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11. (PMID: 19804848) zur Stadt U … Hennies HC (American journal of human genetics 2009) 3 4 23
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  5. Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis. (PMID: 31536960) Moutaoufik MT … Babu M (iScience 2019) 3

Products for STXBP2 Gene

  • Signalway Proteins for STXBP2

Sources for STXBP2 Gene