Aliases for STX4 Gene
External Ids for STX4 Gene
Previous HGNC Symbols for STX4 Gene
Previous GeneCards Identifiers for STX4 Gene
GeneCards Summary for STX4 Gene
STX4 (Syntaxin 4) is a Protein Coding gene. Diseases associated with STX4 include Type 1 Diabetes Mellitus 10 and Leukodystrophy, Hypomyelinating, 6. Among its related pathways are Antigen processing-Cross presentation and Clathrin derived vesicle budding. Gene Ontology (GO) annotations related to this gene include SNARE binding and sphingomyelin phosphodiesterase activator activity. An important paralog of this gene is STX1B.
UniProtKB/Swiss-Prot Summary for STX4 Gene
Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.