Aliases for STX18 Gene
External Ids for STX18 Gene
Previous GeneCards Identifiers for STX18 Gene
This gene encodes a member of the syntaxin family of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) which is part of a membrane tethering complex that includes other SNAREs and several peripheral membrane proteins, and is involved in vesicular transport between the endoplasmic reticulum (ER) and the Golgi complex. The encoded protein is important for the organization of the smooth, rough, and exit site ER subdomains. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
GeneCards Summary for STX18 Gene
STX18 (Syntaxin 18) is a Protein Coding gene. Diseases associated with STX18 include Hemorrhagic Cystitis. Among its related pathways are Golgi-to-ER retrograde transport and Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics. Gene Ontology (GO) annotations related to this gene include protein domain specific binding and SNAP receptor activity.
UniProtKB/Swiss-Prot for STX18 Gene
Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.