Aliases for STMP1 Gene

Aliases for STMP1 Gene

  • Short Transmembrane Mitochondrial Protein 1 2 3 4 5
  • C7orf73 3 4
  • Chromosome 7 Open Reading Frame 73 2
  • Uncharacterized Protein C7orf73 3
  • PL-5283 3

External Ids for STMP1 Gene

Previous HGNC Symbols for STMP1 Gene

  • C7orf73

Summaries for STMP1 Gene

GeneCards Summary for STMP1 Gene

STMP1 (Short Transmembrane Mitochondrial Protein 1) is a Protein Coding gene.

Additional gene information for STMP1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for STMP1 Gene

Genomics for STMP1 Gene

GeneHancer (GH) Regulatory Elements for STMP1 Gene

Promoters and enhancers for STMP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J135661 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 543.5 +0.6 647 3.8 HNRNPK ZBTB40 ZNF217 EP300 CTCF ZSCAN5C MYC NRF1 POLR2G SP1 STMP1 NUP205 RPL15P11 ENSG00000273219 CYREN WDR91 CALD1 RF00026-1039 RNU6-1154P
GH07J135557 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 36.1 -104.2 -104172 2.6 RXRA HNRNPK ZNF217 EP300 CTCF TCF12 SIN3A NRF1 MYC USF1 NUP205 STMP1 RPL15P11 CALD1 SLC13A4 RF00017-6657
GH07J135507 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 35.5 -153.2 -153172 4.2 ZNF217 ZSCAN5C SIN3A NRF1 USF1 POLR2G GTF2E2 PHF8 SIX5 TEAD4 CNOT4 lnc-SLC13A4-2 NUP205 STMP1 CALD1 piR-42694-155
GH07J135672 Enhancer 0.9 ENCODE dbSUPER 51.3 +10.7 10734 1.7 CTCF FOS REST TOE1 RAD21 SMC3 ARNT JUND ZNF654 STAT1 STMP1 RPL15P11 FAM180A CYREN lnc-NUP205-2 RNU6-1154P RF00026-1039
GH07J135560 Promoter/Enhancer 1.1 Ensembl ENCODE 36.9 -100.6 -100552 3.1 ZNF217 TEAD4 RFX1 CTBP1 POLR2A HDAC2 SIN3A YY1 NANOG NEUROD1 STMP1 RPL15P11 NUP205 RF00017-6657
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around STMP1 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for STMP1

Genomic Locations for STMP1 Gene

Genomic Locations for STMP1 Gene
chr7:135,662,473-135,693,418
(GRCh38/hg38)
Size:
30,946 bases
Orientation:
Plus strand
chr7:135,347,221-135,378,166
(GRCh37/hg19)
Size:
30,946 bases
Orientation:
Plus strand

Genomic View for STMP1 Gene

Genes around STMP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
STMP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for STMP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STMP1 Gene

Proteins for STMP1 Gene

  • Protein details for STMP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    E0CX11-STMP1_HUMAN
    Recommended name:
    Short transmembrane mitochondrial protein 1
    Protein Accession:
    E0CX11

    Protein attributes for STMP1 Gene

    Size:
    47 amino acids
    Molecular mass:
    5265 Da
    Quaternary structure:
    No Data Available

neXtProt entry for STMP1 Gene

Post-translational modifications for STMP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STMP1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for STMP1 Gene

Domains & Families for STMP1 Gene

Gene Families for STMP1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for STMP1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

E0CX11

UniProtKB/Swiss-Prot:

STMP1_HUMAN :
  • Belongs to the STMP1 family.
Family:
  • Belongs to the STMP1 family.
genes like me logo Genes that share domains with STMP1: view

No data available for Suggested Antigen Peptide Sequences for STMP1 Gene

Function for STMP1 Gene

Phenotypes From GWAS Catalog for STMP1 Gene

Phenotypes for STMP1 Gene

genes like me logo Genes that share phenotypes with STMP1: view

Animal Model Products

CRISPR Products

miRNA for STMP1 Gene

miRTarBase miRNAs that target STMP1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for STMP1 Gene

Localization for STMP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for STMP1 Gene

Mitochondrion membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for STMP1 gene
Compartment Confidence
mitochondrion 3

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for STMP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005746 mitochondrial respiratory chain IBA 21873635
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0031966 mitochondrial membrane IEA --
genes like me logo Genes that share ontologies with STMP1: view

Pathways & Interactions for STMP1 Gene

PathCards logo

SuperPathways for STMP1 Gene

No Data Available

Interacting Proteins for STMP1 Gene

;

Gene Ontology (GO) - Biological Process for STMP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for STMP1 Gene

Drugs & Compounds for STMP1 Gene

No Compound Related Data Available

Transcripts for STMP1 Gene

mRNA/cDNA for STMP1 Gene

1 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for STMP1 Gene

No ASD Table

Relevant External Links for STMP1 Gene

GeneLoc Exon Structure for
STMP1

Expression for STMP1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for STMP1

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for STMP1 Gene

Orthologs for STMP1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for STMP1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C7orf73 31
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia PL-5283 31
  • 96 (a)
OneToMany
Species where no ortholog for STMP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for STMP1 Gene

ENSEMBL:
Gene Tree for STMP1 (if available)
TreeFam:
Gene Tree for STMP1 (if available)

Paralogs for STMP1 Gene

Pseudogenes.org Pseudogenes for STMP1 Gene

genes like me logo Genes that share paralogs with STMP1: view

No data available for Paralogs for STMP1 Gene

Variants for STMP1 Gene

Additional dbSNP identifiers (rs#s) for STMP1 Gene

Structural Variations from Database of Genomic Variants (DGV) for STMP1 Gene

Variant ID Type Subtype PubMed ID
nsv608460 CNV gain 21841781
nsv966890 CNV duplication 23825009

Variation tolerance for STMP1 Gene

Gene Damage Index Score: 0.66; 14.03% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for STMP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
STMP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for STMP1 Gene

Disorders for STMP1 Gene

Additional Disease Information for STMP1

No disorders were found for STMP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for STMP1 Gene

Publications for STMP1 Gene

  1. Functional prediction and physiological characterization of a novel short trans-membrane protein 1 as a subunit of mitochondrial respiratory complexes. (PMID: 23073385) Zhang D … Trudeau VL (Physiological genomics 2012) 2 3 4 54
  2. Identification of membrane proteins by tandem mass spectrometry of protein ions. (PMID: 17720804) Carroll J … Walker JE (Proceedings of the National Academy of Sciences of the United States of America 2007) 2 3 54
  3. N-terminome analysis of the human mitochondrial proteome. (PMID: 25944712) Vaca Jacome AS … Carapito C (Proteomics 2015) 4 54
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 54

Products for STMP1 Gene

Sources for STMP1 Gene