Aliases for STMND1 Gene

Aliases for STMND1 Gene

  • Stathmin Domain Containing 1 2 3 5
  • Stathmin Domain-Containing Protein 1 3 4

External Ids for STMND1 Gene

Summaries for STMND1 Gene

GeneCards Summary for STMND1 Gene

STMND1 (Stathmin Domain Containing 1) is a Protein Coding gene. Diseases associated with STMND1 include Patent Foramen Ovale. Gene Ontology (GO) annotations related to this gene include tubulin binding. An important paralog of this gene is STMN3.

Additional gene information for STMND1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for STMND1 Gene

Genomics for STMND1 Gene

GeneHancer (GH) Regulatory Elements for STMND1 Gene

Promoters and enhancers for STMND1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around STMND1 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for STMND1

Genomic Locations for STMND1 Gene

Genomic Locations for STMND1 Gene
chr6:17,102,258-17,131,372
(GRCh38/hg38)
Size:
29,115 bases
Orientation:
Plus strand
chr6:17,102,489-17,131,603
(GRCh37/hg19)
Size:
29,115 bases
Orientation:
Plus strand

Genomic View for STMND1 Gene

Genes around STMND1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
STMND1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for STMND1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STMND1 Gene

Proteins for STMND1 Gene

  • Protein details for STMND1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BQB6-STMD1_HUMAN
    Recommended name:
    Stathmin domain-containing protein 1
    Protein Accession:
    H3BQB6

    Protein attributes for STMND1 Gene

    Size:
    276 amino acids
    Molecular mass:
    30984 Da
    Quaternary structure:
    No Data Available

neXtProt entry for STMND1 Gene

Post-translational modifications for STMND1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STMND1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for STMND1 Gene

Domains & Families for STMND1 Gene

Gene Families for STMND1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for STMND1 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with STMND1: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for STMND1 Gene

Function for STMND1 Gene

Phenotypes From GWAS Catalog for STMND1 Gene

Gene Ontology (GO) - Molecular Function for STMND1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015631 tubulin binding IBA 21873635
genes like me logo Genes that share ontologies with STMND1: view

Phenotypes for STMND1 Gene

genes like me logo Genes that share phenotypes with STMND1: view

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for STMND1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for STMND1 Gene

Localization for STMND1 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Actin filaments (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for STMND1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA 21873635
GO:0043005 neuron projection IBA 21873635
genes like me logo Genes that share ontologies with STMND1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for STMND1 Gene

Pathways & Interactions for STMND1 Gene

PathCards logo

SuperPathways for STMND1 Gene

No Data Available

Interacting Proteins for STMND1 Gene

;

Gene Ontology (GO) - Biological Process for STMND1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007019 microtubule depolymerization IBA 21873635
GO:0031110 regulation of microtubule polymerization or depolymerization IBA 21873635
GO:0031175 neuron projection development IBA 21873635
GO:0051493 regulation of cytoskeleton organization IBA 21873635
genes like me logo Genes that share ontologies with STMND1: view

No data available for Pathways by source and SIGNOR curated interactions for STMND1 Gene

Drugs & Compounds for STMND1 Gene

No Compound Related Data Available

Transcripts for STMND1 Gene

mRNA/cDNA for STMND1 Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for STMND1

Alternative Splicing Database (ASD) splice patterns (SP) for STMND1 Gene

No ASD Table

Relevant External Links for STMND1 Gene

GeneLoc Exon Structure for
STMND1

Expression for STMND1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for STMND1 Gene

mRNA differential expression in normal tissues according to GTEx for STMND1 Gene

This gene is overexpressed in Testis (x13.4), Pancreas (x8.3), and Fallopian Tube (x6.0).

Protein differential expression in normal tissues from HIPED for STMND1 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (68.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for STMND1 Gene



Protein tissue co-expression partners for STMND1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for STMND1

SOURCE GeneReport for Unigene cluster for STMND1 Gene:

Hs.677399
genes like me logo Genes that share expression patterns with STMND1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for STMND1 Gene

Orthologs for STMND1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for STMND1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC747449 30
  • 97.95 (n)
cow
(Bos Taurus)
Mammalia STMND1 31 30
  • 81.85 (n)
OneToOne
dog
(Canis familiaris)
Mammalia STMND1 31 30
  • 77.24 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Stmnd1 17 31 30
  • 76.24 (n)
rat
(Rattus norvegicus)
Mammalia LOC102554838 30
  • 74.3 (n)
oppossum
(Monodelphis domestica)
Mammalia STMND1 31
  • 53 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CU856207.1 31
  • 28 (a)
OneToOne
Species where no ortholog for STMND1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for STMND1 Gene

ENSEMBL:
Gene Tree for STMND1 (if available)
TreeFam:
Gene Tree for STMND1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for STMND1: view image

Paralogs for STMND1 Gene

Paralogs for STMND1 Gene

genes like me logo Genes that share paralogs with STMND1: view

Variants for STMND1 Gene

Additional dbSNP identifiers (rs#s) for STMND1 Gene

Structural Variations from Database of Genomic Variants (DGV) for STMND1 Gene

Variant ID Type Subtype PubMed ID
esv2664889 CNV deletion 23128226
esv3608206 CNV loss 21293372
nsv5213 CNV deletion 18451855

Variation tolerance for STMND1 Gene

Gene Damage Index Score: 1.93; 35.87% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for STMND1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
STMND1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for STMND1 Gene

Disorders for STMND1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for STMND1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
patent foramen ovale
  • atrial septal defect within oval fossa
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for STMND1

genes like me logo Genes that share disorders with STMND1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for STMND1 Gene

Publications for STMND1 Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 54
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 4 54

Products for STMND1 Gene

Sources for STMND1 Gene