Aliases for STMN1 Gene
External Ids for STMN1 Gene
Previous HGNC Symbols for STMN1 Gene
Previous GeneCards Identifiers for STMN1 Gene
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
GeneCards Summary for STMN1 Gene
STMN1 (Stathmin 1) is a Protein Coding gene. Diseases associated with STMN1 include Acute Leukemia and Pancreatic Intraductal Papillary-Mucinous Adenoma. Among its related pathways are Aurora B signaling and MAPK signaling pathway. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and tubulin binding. An important paralog of this gene is STMN2.
UniProtKB/Swiss-Prot Summary for STMN1 Gene
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity).