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STK38L (Serine/Threonine Kinase 38 Like) is a Protein Coding gene. Diseases associated with STK38L include Ossification Of The Posterior Longitudinal Ligament Of Spine and Warburg Micro Syndrome 3. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is STK38.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000166 | nucleotide binding | IEA | -- |
GO:0000287 | magnesium ion binding | IDA | 15067004 |
GO:0003779 | actin binding | IEA | -- |
GO:0004672 | protein kinase activity | IEA | -- |
GO:0004674 | protein serine/threonine kinase activity | IBA,IDA | 15037617 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IEA,IDA | 15037617 |
GO:0005829 | cytosol | IDA | -- |
GO:0005856 | cytoskeleton | IEA | -- |
GO:0015629 | actin cytoskeleton | IEA,ISS | -- |
GO:0016020 | membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006468 | protein phosphorylation | IEA,IDA | 15037617 |
GO:0016310 | phosphorylation | IEA | -- |
GO:0018105 | peptidyl-serine phosphorylation | IBA | 21873635 |
GO:0035556 | intracellular signal transduction | IDA | 15067004 |
GO:0051128 | regulation of cellular component organization | IEA,ISS | -- |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
ADP |
|
58-64-0 |
|
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | STK38L 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | STK38L 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | STK38L 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | STK38L 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | STK38L 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Stk38l 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Stk38l 30 |
|
||
Chicken (Gallus gallus) |
Aves | STK38L 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | STK38L 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | stk38l 30 |
|
||
Str.11890 30 |
|
||||
Zebrafish (Danio rerio) |
Actinopterygii | stk38l 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | trc 31 32 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | sax-1 30 31 32 |
|
OneToMany | |
K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0D07810g 30 |
|
||
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | CBK1 30 31 |
|
OneToMany | |
A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AFR035W 30 |
|
||
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT4G33080 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os01g0186700 30 |
|
||
Barley (Hordeum vulgare) |
Liliopsida | Hv.1876 30 |
|
||
Wheat (Triticum aestivum) |
Liliopsida | Ta.6269 30 |
|
||
Corn (Zea mays) |
Liliopsida | Zm.5558 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany | |
Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | orb6 30 |
|
||
Bread mold (Neurospora crassa) |
Ascomycetes | NCU07296 30 |
|
||
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.1672 30 |
|
SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs371435415 | Likely Benign: not provided | 27,322,413(+) |
A/G NM_015000.4(STK38L):c.1353A>G (p.Gln451=) |
SYNONYMOUS | |
rs56140810 | Benign: not provided | 27,297,738(+) |
G/T NM_015000.4(STK38L):c.18G>T (p.Gly6=) |
SYNONYMOUS | |
VAR_041199 | - |
p.Gly99Ala |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1406n100 | CNV | gain | 25217958 |
dgv2417n54 | CNV | gain | 21841781 |
dgv263e214 | CNV | gain | 21293372 |
dgv271e199 | CNV | deletion | 23128226 |
dgv786n106 | CNV | deletion | 24896259 |
esv1525868 | CNV | deletion | 17803354 |
esv2395169 | CNV | deletion | 18987734 |
esv2598897 | CNV | deletion | 19546169 |
esv2667338 | CNV | deletion | 23128226 |
esv2672021 | CNV | deletion | 23128226 |
esv2745664 | CNV | deletion | 23290073 |
esv2745667 | CNV | deletion | 23290073 |
esv3253385 | CNV | deletion | 24192839 |
esv3548925 | CNV | deletion | 23714750 |
esv3628932 | CNV | loss | 21293372 |
esv3628933 | CNV | gain | 21293372 |
esv3628934 | CNV | loss | 21293372 |
esv4652 | CNV | loss | 18987735 |
esv7285 | CNV | loss | 19470904 |
esv996338 | CNV | deletion | 20482838 |
esv997751 | CNV | deletion | 20482838 |
nsv1070100 | CNV | deletion | 25765185 |
nsv436825 | CNV | insertion | 17901297 |
nsv469175 | CNV | loss | 19166990 |
nsv521872 | CNV | gain | 19592680 |
nsv557808 | CNV | loss | 21841781 |
nsv832356 | CNV | gain | 17160897 |
nsv958659 | CNV | deletion | 24416366 |
nsv975462 | CNV | duplication | 23825009 |
Disorder | Aliases | PubMed IDs |
---|---|---|
ossification of the posterior longitudinal ligament of spine |
|
|
warburg micro syndrome 3 |
|
|
warburg micro syndrome 2 |
|
|
diffuse idiopathic skeletal hyperostosis |
|
|
cone-rod dystrophy 6 |
|
|