Aliases for STK19 Gene
External Ids for STK19 Gene
Previous GeneCards Identifiers for STK19 Gene
This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants. [provided by RefSeq, Jul 2008]
GeneCards Summary for STK19 Gene
STK19 (Serine/Threonine Kinase 19) is a Protein Coding gene. Diseases associated with STK19 include Hyperpigmentation Of The Skin and Melanoma. Among its related pathways are Sweet Taste Signaling. Gene Ontology (GO) annotations related to this gene include protein serine/threonine kinase activity.
UniProtKB/Swiss-Prot Summary for STK19 Gene
Serine/threonine-protein kinase that acts as a key regulator of NRAS signaling by mediating phosphorylation of NRAS at 'Ser-89', thereby enhancing NRAS-binding to its downstream effectors.