Aliases for STK16 Gene
External Ids for STK16 Gene
Previous GeneCards Identifiers for STK16 Gene
GeneCards Summary for STK16 Gene
STK16 (Serine/Threonine Kinase 16) is a Protein Coding gene. Diseases associated with STK16 include Diffuse Mesangial Sclerosis and Atrial Septal Defect 6. Among its related pathways are Sweet Taste Signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AAK1.
UniProtKB/Swiss-Prot Summary for STK16 Gene
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.