Aliases for STAP2 Gene
External Ids for STAP2 Gene
Previous GeneCards Identifiers for STAP2 Gene
This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
GeneCards Summary for STAP2 Gene
STAP2 (Signal Transducing Adaptor Family Member 2) is a Protein Coding gene. Diseases associated with STAP2 include Bone Angioendothelial Sarcoma and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Signaling by GPCR and Tyrosine Kinases / Adaptors. An important paralog of this gene is STAP1.
UniProtKB/Swiss-Prot Summary for STAP2 Gene
Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.