Aliases for STAM Gene
Aliases for STAM Gene
External Ids for STAM Gene
- HGNC: 11357
- Entrez Gene: 8027
- Ensembl: ENSG00000136738
- OMIM: 601899
- UniProtKB: Q92783
Previous GeneCards Identifiers for STAM Gene
- GC10P017668
- GC10P017836
- GC10P017690
- GC10P017726
- GC10P017686
- GC10P017598
Summaries for STAM Gene
-
This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
GeneCards Summary for STAM Gene
STAM (Signal Transducing Adaptor Molecule) is a Protein Coding gene. Among its related pathways are Listeria monocytogenes entry into host cells and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include SH3/SH2 adaptor activity. An important paralog of this gene is STAM2.
UniProtKB/Swiss-Prot for STAM Gene
-
Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STAM Gene
Genomics for STAM Gene
GeneHancer (GH) Regulatory Elements for STAM Gene
Promoters and enhancers for STAM Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH10I017642 | Promoter/Enhancer | 2.5 | EPDnew Ensembl ENCODE dbSUPER | 563.6 | +3.0 | 3030 | 9.6 | HDGF PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 | STAM LOC105376438 HACD1 STAM-AS1 GC10P017641 | |
| GH10I017654 | Enhancer | 1.6 | FANTOM5 Ensembl ENCODE dbSUPER | 22.9 | +12.1 | 12107 | 2.5 | HDGF FOXA2 IRF4 TCF12 ZNF207 FOS ATF7 RUNX3 NCOA1 JUNB | STAM HACD1 ST8SIA6 LOC105376438 | |
| GH10I017672 | Enhancer | 1.3 | Ensembl ENCODE dbSUPER | 25 | +29.5 | 29521 | 2.4 | PKNOX1 FOXA2 ARID4B KLF17 SIN3A RAD21 ETS1 ZNF335 SMARCC2 RCOR1 | STAM HACD1 LOC105376438 | |
| GH10I017664 | Enhancer | 1.3 | FANTOM5 Ensembl ENCODE dbSUPER | 13.6 | +21.7 | 21665 | 2.4 | JUN CEBPG CHAMP1 FOSL1 FOSL2 FOS HOMEZ CEBPB USF2 EP300 | VIM STAM ST8SIA6 LOC105376438 | |
| GH10I017684 | Enhancer | 0.8 | ENCODE dbSUPER | 21.9 | +41.0 | 40951 | 1.2 | DPF2 ZBTB40 BATF ATF2 RELA ZNF217 IKZF1 NBN ZNF143 RUNX3 | STAM VIM LOC105376438 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around STAM on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for STAM Gene
Genomic Locations for STAM Gene
- chr10:17,644,125-17,716,824
- (GRCh38/hg38)
- Size:
- 72,700 bases
- Orientation:
- Plus strand
- chr10:17,686,124-17,758,823
- (GRCh37/hg19)
Genomic View for STAM Gene
Genes around STAM on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10p12.33 by Ensembl
- 10p12.33 by Entrez Gene
- 10p12.33 by HGNC
STAM Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for STAM Gene
Proteins for STAM Gene
-
Protein details for STAM Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q92783-STAM1_HUMAN
- Recommended name:
- Signal transducing adapter molecule 1
- Protein Accession:
- Q92783
- B0YJ99
- D3DRU5
- Q8N6D9
Protein attributes for STAM Gene
- Size:
- 540 amino acids
- Molecular mass:
- 59180 Da
- Quaternary structure:
-
- Component of the ESCRT-0 complex composed of STAM or STAM2 and HGS (PubMed:11687594, PubMed:9407053, PubMed:19278655). Probably part of a complex at least composed of HSG, STAM and EPS15 (PubMed:12551915). Found in a complex with HGS and E3 ligase ITCH and DTX3L (PubMed:24790097). Interacts with E3 ligase DTX3L; the interaction brings together STAM and HSG, promotes their recruitment to early endosomes and decreases STAM and HGS ubiquitination by ITCH (PubMed:24790097). Interacts with STAMBP/AMSH (PubMed:10383417). Interacts with PDGFRB (PubMed:20494825). Interacts with LITAF; the interaction is direct (PubMed:23166352). Identified in a complex with HGS and LITAF (PubMed:23166352).
Protein Expression for STAM Gene
Post-translational modifications for STAM Gene
- Phosphorylated on Tyr-198. Phosphorylated in response to IL2, IL3, IL4, IL7, CSF2/GM-CSF, EGF and PDGFB. Phosphorylated by activated PDGFRB.
- Ubiquitinated by ITCH.
- Ubiquitination at isoforms=299, isoforms=2133, posLast=154154, posLast=185185, and posLast=373373
- Modification sites at PhosphoSitePlus
Other Protein References for STAM Gene
Antibody Products
-
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-
Cloud-Clone Corp. Antibodies for STAM
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-
Santa Cruz Biotechnology (SCBT) Antibodies for STAM
Protein Products
- R&D Systems Proteins and Enzymes for STAM (STAM-1)
-
OriGene Purified Proteins for STAM
- Search Origene for MassSpec and Protein Over-expression Lysates for STAM
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-
Cloud-Clone Corp. Proteins for STAM
- Search GeneTex for Proteins for STAM
Assay Products
- antibodies-online: Search results for available STAM related products ranked by validation data
No data available for DME Specific Peptides for STAM Gene
Domains & Families for STAM Gene
Gene Families for STAM Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for STAM Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for STAM Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q92783UniProtKB/Swiss-Prot:
STAM1_HUMAN :- The VHS domain mediates high-avidity binding to Lys63-linked and Lys48-linked polyubiquitinated cargos.
- Belongs to the STAM family.
- Domain:
-
- The VHS domain mediates high-avidity binding to Lys63-linked and Lys48-linked polyubiquitinated cargos.
- Family:
-
- Belongs to the STAM family.
Function for STAM Gene
Molecular function for STAM Gene
- GENATLAS Biochemistry:
- signal-transducin adaptor molecule involved in cytokine-mediated signal transduction
- UniProtKB/Swiss-Prot Function:
- Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005070 | SH3/SH2 adaptor activity | TAS | 8780729 |
| GO:0005515 | protein binding | IPI | 10383417 |
| GO:0044389 | ubiquitin-like protein ligase binding | IPI | 24790097 |
Phenotypes for STAM Gene
- MGI mutant phenotypes for STAM:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for STAM:
Animal Models for STAM Gene
- MGI Knock Outs for STAM:
-
- Stam tm1Sug
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for STAM
-
-
ViGene Biosciences lentiviral particle packaged cDNA for STAM gene
-
ViGene Biosciences ready-to-package AAV shRNAs for STAM gene
- Search ViGene Biosciences for STAM
CRISPR Products
-
OriGene CRISPR knockouts for STAM
- genomics-online: gRNA clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
- Applied Biological Materials CRISPR for STAM
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for STAM
- GenScript: Design CRISPR guide RNA sequences for STAM
miRNA for STAM Gene
- miRTarBase miRNAs that target STAM
-
- hsa-mir-215-5p (MIRT024512)
- hsa-mir-192-5p (MIRT026819)
- hsa-let-7e-5p (MIRT051525)
- hsa-mir-142-3p (MIRT177133)
- hsa-mir-3668 (MIRT177138)
- hsa-mir-573 (MIRT328233)
- hsa-mir-3616-5p (MIRT328235)
- hsa-mir-4635 (MIRT328236)
- hsa-mir-4670-3p (MIRT328237)
- hsa-mir-578 (MIRT544027)
- hsa-mir-526b-5p (MIRT544028)
- hsa-mir-4724-3p (MIRT544029)
- hsa-mir-1277-5p (MIRT707216)
- hsa-mir-1277-3p (MIRT707217)
- hsa-mir-4753-3p (MIRT707218)
- hsa-mir-190a-3p (MIRT707219)
- hsa-mir-4789-5p (MIRT707220)
- hsa-mir-3941 (MIRT707221)
- hsa-mir-376a-2-5p (MIRT707222)
- hsa-mir-3935 (MIRT707223)
- hsa-mir-130b-5p (MIRT707224)
- hsa-mir-3675-3p (MIRT707225)
- hsa-mir-5011-5p (MIRT707226)
- hsa-mir-4789-3p (MIRT707227)
- hsa-mir-603 (MIRT707228)
- hsa-mir-362-3p (MIRT707229)
- hsa-mir-329-3p (MIRT707230)
- hsa-mir-8485 (MIRT707231)
- hsa-mir-641 (MIRT707232)
- hsa-mir-3617-5p (MIRT707233)
miRNA Products
- Search ViGene Biosciences for STAM
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for STAM
- Browse OriGene Inhibitory RNA Products For STAM
- genomics-online: shRNA clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for STAM gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for STAM
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for STAM
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for STAM
- Applied Biological Materials Clones for STAM
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for STAM
-
ViGene Biosciences adenoviral particle packaged cDNA for STAM gene
-
ViGene Biosciences lentiviral particle packaged cDNA for STAM gene
-
ViGene Biosciences ready-to-package AAV shRNAs for STAM gene
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for STAM Gene
Localization for STAM Gene
Subcellular locations from UniProtKB/Swiss-Prot for STAM Gene
- Cytoplasm. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| endosome | 5 |
| nucleus | 2 |
| lysosome | 2 |
| golgi apparatus | 1 |
- Vesicles (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005768 | endosome | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for STAM Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Listeria monocytogenes entry into host cells | ||
| 2 | Clathrin-mediated endocytosis | ||
| 3 | HIV Life Cycle |
.45
|
|
| 4 | Vesicle-mediated transport | ||
| 5 | Metabolism of proteins | ||
Pathways by source for STAM Gene
2 BioSystems pathways for STAM Gene
18 Reactome pathways for STAM Gene
2 KEGG pathways for STAM Gene
1 Qiagen pathway for STAM Gene
1 Cell Signaling Technology pathway for STAM Gene
Interacting Proteins for STAM Gene
Selected Interacting proteins:
ENSP00000366746
Q92783-STAM1_HUMAN
for STAM Gene via
STRING
IID
UniProtKB
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0006886 | intracellular protein transport | IEA | -- |
| GO:0007165 | signal transduction | TAS | 8780729 |
| GO:0009967 | positive regulation of signal transduction | IEA | -- |
| GO:0015031 | protein transport | IEA | -- |
Transcripts for STAM Gene
mRNA/cDNA for STAM Gene
- (11) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (146) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for STAM Gene
CRISPR Products
-
OriGene CRISPR knockouts for STAM
- genomics-online: gRNA clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
- Applied Biological Materials CRISPR for STAM
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for STAM
- GenScript: Design CRISPR guide RNA sequences for STAM
miRNA Products
- Search ViGene Biosciences for STAM
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for STAM
- Browse OriGene Inhibitory RNA Products For STAM
- genomics-online: shRNA clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for STAM gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for STAM
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for STAM
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for STAM
- Applied Biological Materials Clones for STAM
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for STAM Gene
This gene is overexpressed in Pancreas (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for STAM Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of STAM Gene:
STAMSOURCE GeneReport for Unigene cluster for STAM Gene:
Hs.335391mRNA Expression by UniProt/SwissProt for STAM Gene:
Q92783-STAM1_HUMAN
Tissue specificity:
Ubiquitously expressed.
Evidence on tissue expression from TISSUES for STAM Gene
- Nervous system(4.8)
- Blood(4.2)
- Liver(4.2)
Primer Products
-
OriGene qPCR primer pairs for STAM
- genomics-online: primer clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for STAM Gene
Orthologs for STAM Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | STAM 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | STAM 33 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | STAM 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | STAM 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Stam 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Stam 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | STAM 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | STAM 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | STAM 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | stam 33 |
|
||
| MGC76231 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | stam 33 34 |
|
||
| wufv75b10 33 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP008494 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Stam 35 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | stam-1 33 34 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | HSE1 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.1021 34 |
|
OneToMany | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.2766 33 |
|
- Species where no ortholog for STAM was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for STAM Gene
(7) SIMAP similar genes for STAM Gene using alignment to 4 proteins:
Variants for STAM Gene
| SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| VAR_036348 | A colorectal cancer sample | p.Gly212Asp | |||
| rs1000012853 | -- | 17,667,088(+) | A/G | genic_upstream_transcript_variant, intron_variant | |
| rs1000172040 | -- | 17,653,010(+) | G/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000185728 | -- | 17,688,332(+) | A/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000203028 | -- | 17,652,760(+) | G/A | genic_upstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2618457 | CNV | insertion | 19546169 |
| esv3303988 | CNV | mobile element insertion | 20981092 |
| esv3305237 | CNV | mobile element insertion | 20981092 |
| esv3406363 | CNV | insertion | 20981092 |
| esv3408186 | CNV | insertion | 20981092 |
| esv3447679 | CNV | insertion | 20981092 |
| esv3622497 | CNV | loss | 21293372 |
Residual Variation Intolerance Score:
10.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.62;
31.09% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for STAM Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for STAM Gene
Disorders for STAM Gene
Additional Disease Information for STAM
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for STAM Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for STAM Gene
Publications for STAM Gene
- Hybrid structural model of the complete human ESCRT-0 complex. (PMID: 19278655) Ren X … Hurley JH (Structure (London, England : 1993) 2009) 3 4 22 58
- STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes. (PMID: 12551915) Bache KG … Stenmark H (The Journal of biological chemistry 2003) 3 4 22 58
- Possible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokines. (PMID: 10383417) Tanaka N … Sugamura K (The Journal of biological chemistry 1999) 3 4 22 58
- Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth. (PMID: 9407053) Asao H … Sugamura K (The Journal of biological chemistry 1997) 3 4 22 58
- Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM. (PMID: 8780729) Takeshita T … Sugamura K (Biochemical and biophysical research communications 1996) 2 3 4 58
Products for STAM Gene
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for STAM
- VectorBuilder custom plasmid, inducible vectors for STAM
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for STAM
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for STAM
- antibodies-online: Search results for 85 available STAM Antibodies ranked by validation data
- Compare Top STAM Antibodies
- antibodies-online: Search results for available STAM related products ranked by validation data
- antibodies-online: Search results for 9 available STAM Proteins ranked by validation data
- Compare Top STAM Proteins
- GeneTex STAM antibody for STAM
- Search GeneTex for Proteins for STAM
- ViGene Biosciences adenoviral particle packaged cDNA for STAM gene
- ViGene Biosciences lentiviral particle packaged cDNA for STAM gene
- ViGene Biosciences ready-to-package AAV shRNAs for STAM gene
- Search ViGene Biosciences for STAM
- Santa Cruz Biotechnology (SCBT) Antibodies for STAM
- Search Santa Cruz Biotechnology (SCBT) for STAM siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for STAM
- Horizon Cell Lines for STAM
- genomics-online: cdna clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
- orf clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
- genomics-online: gRNA clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
- genomics-online: primer clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
- genomics-online: shRNA clones - Search results for 108 available STAM gene related products
- Overview of 108 available STAM gene related products
Sources for STAM Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
