Aliases for ST8SIA6 Gene
External Ids for ST8SIA6 Gene
Previous HGNC Symbols for ST8SIA6 Gene
Previous GeneCards Identifiers for ST8SIA6 Gene
This gene encodes a member of the glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
GeneCards Summary for ST8SIA6 Gene
ST8SIA6 (ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 6) is a Protein Coding gene. Diseases associated with ST8SIA6 include Acute Hemorrhagic Conjunctivitis. Among its related pathways are Metabolism of proteins and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include sialyltransferase activity. An important paralog of this gene is ST8SIA5.
UniProtKB/Swiss-Prot Summary for ST8SIA6 Gene
Prefers O-glycans to N-glycans or glycolipids as acceptor substrates. The minimal acceptor substrate is the NeuAc-alpha-2,3(6)-Gal sequence at the non-reducing end of their carbohydrate groups (By similarity).