Aliases for ST8SIA5 Gene
External Ids for ST8SIA5 Gene
Previous HGNC Symbols for ST8SIA5 Gene
Previous GeneCards Identifiers for ST8SIA5 Gene
The protein encoded by this gene is a type II membrane protein that may be present in the Golgi apparatus. The encoded protein, which is a member of glycosyltransferase family 29, may be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, and GT3 from GD1a, GT1b, GM1b, and GD3, respectively. [provided by RefSeq, Jul 2008]
GeneCards Summary for ST8SIA5 Gene
ST8SIA5 (ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 5) is a Protein Coding gene. Diseases associated with ST8SIA5 include Spastic Paraplegia 26, Autosomal Recessive. Among its related pathways are Metabolism of proteins and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include sialyltransferase activity and alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. An important paralog of this gene is ST8SIA6.
UniProtKB/Swiss-Prot for ST8SIA5 Gene
May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively.