Aliases for SSR2 Gene
External Ids for SSR2 Gene
Previous GeneCards Identifiers for SSR2 Gene
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008]
GeneCards Summary for SSR2 Gene
SSR2 (Signal Sequence Receptor Subunit 2) is a Protein Coding gene. Diseases associated with SSR2 include Synostoses, Tarsal, Carpal, And Digital and Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type Iii. Among its related pathways are Gene Expression and Viral mRNA Translation.
UniProtKB/Swiss-Prot Summary for SSR2 Gene
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.